| Aim: | To provide the participants with a detailed theoretical and practical knowledge of tracer kinetic principles in physiology, nuclear medicine and magnetic resonance imaging (MRI). The focus of the course is to understand and set-up simple kinetic models for modeling of neuroreceptor systems based on PET and SPECT imaging. |
| Content: | -basic mathematics,
-introduction to PET, SPECT and MRI and MATLAB, -steady state, -indicator diffusion, -Fick's principle, -clearance, -extraction, -mean transit time, -convolution and impulse response, -residue detection, -Kety-Schmidt method, -receptor kinetics, -models of glucose consumption (Sokolof), -water exchange, -perfusion measurement in magnetic resonance, -all aspects of the modeling process will be illustrated with computer exercises, -on the last day the participants will bring and discuss their own imaging data with particular focus on quantification. |
| Participants: | Ph.D. students in medicine, biophysics, physics, chemistry, and biology.
Graduates with interest in this field.
Basic knowledge of mathematics (exponential function, integration, differentiation) is recommended as part of the course will be setting up differential equations. |
| Language: | English |
| Form: | Interactive teaching with examples and PC exercises |
| Course material,
program and practical information: |
Can be found here. |
| ECTS-credits: | 2 |
| Teachers: | Gitte Moos Knudsen, professor, MD, Neurobiology Research Unit, Rigshospitalet
Ian Law, PhD, MD, Dept. Clinical Physiology, Rigshospitalet Egill Rostrup, MD, MSc, MR Department, Hvidovre Hospital Steen Hasselbalch, MD, DMSc, Neurobiology Research Unit, Rigshospitalet Henrik B.W. Larsson, professor, MD, PhD, Functional and diagnostic MR Unit, Glostrup Hospital Lars Pinborg, MD, Department of Neurology, Rigshospitalet Karam Sidaros, PhD, MR Department, Hvidovre Hospital Claus Svarer, PhD, Neurobiology Research Unit, Rigshospitalet Lars Hanson, PhD, MR Department, Hvidovre Hospital Ling Feng, PhD, Neurobiology Research Unit, Rigshospitalet |
| Date: | February 31.1-4.2.2011 |
| Place: | Neurobiology Research Unit, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark |
| Registration: | The registration is handled through the University of Copenhagen |
| Contact: | Dorthe Givard
e-mail: dorthe#nru.dk ([kincourse] in subject) |