Publications

Disputatser og phd-afhandlinger
Haugbøl S. PhD-afhandling: Imaging brain serotonin 2A receptors: Methodological and genetic aspects and involvement in Tourette’s syndrome. København: Eget forlag 2007:1-79. Forsvaret d. 2. februar 2007 ved Københavns Universitet, Det Sundhedsvidenskabelige Fakultet.
Law I. Disputats: Human brain mapping under increasing cognitive complexity using regional cerebral blood flow measurements and positron emission tomography. København: Lægeforeningens Forlag 2007:1-94. Forsvaret d. 31. august 2007 ved Københavns Universitet, Det Sundhedsvidenskabelige Fakultet.
Møller K. Disputats: Cerebral blood flow and metabolism in adults with acute bacterial meningitis. København: Eget forlag 2007:1-64. Forsvaret d. 24. august 2007 ved Københavns Universitet, Det Sundhedsvidenskabelige Fakultet.
Strauss GI. Disputats: The effect of hyperventilation upon cerebral blood flow and metabolism in patients with fulminant hepatic failure. København: Lægeforeningens Forlag 2007:1-45. Forsvaret d. 30. marts 2007 ved Københavns Universitet, Det Sundhedsvidenskabelige Fakultet.
Trajkovska V. PhD-afhandling: Brain-derived neurotrophic factor (BDNF) and glucocorticoids: Influence on serotonin 2A receptors and relation to major depression. København: Eget forlag 2007:1-64. Forsvaret d. 5. oktober 2007 ved Københavns Universitet, Det Sundhedsvidenskabelige Fakultet.

Originale publikationer i peer-reviewed journals
Balslev D, Cole J, Miall RC. Proprioception contributes to the sense of agency during visual observation of hand movements: evidence from temporal judgments of action. J Cogn Neurosci 2007;19:1535-41.
Christensen MS, Lundbye-Jensen J, Geertsen SS, Petersen TH, Paulson OB, Nielsen JB. Premotor cortex modulates somatosensory cortex during voluntary movements without proprioceptive feedback. Nat Neurosci 2007;10:417-9.
Dyrby TB, Sogaard LV, Parker GJ, Alexander DC, Lind NM, Baare WF, Hay-Schmidt A, Eriksen N, Pakkenberg B, Paulson OB, Jelsing J. Validation of in vitro probabilistic tractography. Neuroimage 2007;37:1267-77.
Elfving B, Madsen J, Knudsen GM. Neuroimaging of the serotonin reuptake site requires high affinity ligands. Synapse 2007;61:882-8.
Gerlach C. A review of functional imaging studies on category specificity. J Cogn Neuroscience 2007;19:296-314.
Hasselbalch SG, Hansen ES, Jacobsen TB, Pinborg LH, Lønborg JH, Bolwig TG. Reduced midbrain-pons serotonin transporter binding in patients with obsessive-compulsive disorder. Acta Psychiatr Scand 2007;115:388-94.
Haugbol S, Pinborg LH, Regeur L, Hansen ES, Bolwig TG, Nielsen FA, Svarer C, Skovgaard LT, Knudsen GM. Cerebral 5-HT2A receptor binding is increased in patients with Tourette's syndrome.
Int J Neuropsychopharmacol 2007 Apr;10(2):245-52.
Haugbøl S, Pinborg LH, Arfan HM, Frøkjær V, Madsen J, Dyrby TB, Svarer C, Knudsen GM. Reproducibility of 5-HT2A receptor measurements and sample size estimations with [18F]altanserin PET using a bolus/infusion approach. Eur J Nucl Med Mol Imaging 2007;34:910-5.
Kornum BR, Thygesen KS, Nielsen TR, Knudsen GM,  Lind NM. The effect of the inter-phase interval in the spontaneous object recognition test for pigs. Behav Brain Res 2007;181:210-7.
Olling JD, Ulrichsen J, Haugbøl S, Glenthøj B, Hemmingsen R, Woldbye DP. Decreased gene expression of neuropeptide Y and its receptors in hippocampal regions during ethanol withdrawal in rats. Neurosci Lett 2007;424:160-4.
Pedersen M, Brandt CT, Knudsen GM, Ostergaard C, Skinhoj P, Frimodt-Moller N, Moller K. Cerebral blood flow autoregulation in early experimental S. pneumoniae meningitis. J Appl Physiol 2007;102(1):72-8.
Pinborg LH, Videbaek C, Ziebell M, Mackeprang T, Friberg L, Rasmussen H, Knudsen GM, Glenthoj BY. [123I]Epidepride binding to cerebellar dopamine D2/D3 receptors is displaceable: Implications for the use of cerebellum as a reference region. Neuroimage 2007;34:1450-3.
Rowe JB, Sakai K, Lund TE, Ramsøy T, Christensen MS, Baare WFC, Paulson OB, Passingham RE. Is the prefrontal cortex necessary for establishing cognitive sets? J Neuroscience 2007;27:13303-10.
Severino M, Pedersen AF, Trajkovska V, Christensen E, Lohals R, Veng LM, Knudsen GM, Aznar S. Selective immunolesion of cholinergic neurons leads to long-term changes in 5-HT2A receptor levels in hippocampus and frontal cortex. Neurosci Lett 2007;428:47-51.
Starrfelt R, Gerlach C. The visual what for area: Words and pictures in the left fusiform gyrus. Neuroimage 2007;35:334-42.
Trajkovska V, Marcussen AB, Vinberg M, Hartvig P, Aznar S, Knudsen GM. Measurements of brain-derived neurotrophic factor: Methodological aspects and demographical data. Brain Res Bull 2007;73:143-9.
Ziebell M, Thomsen G, Knudsen GM, de Nijs R, Svarer C, Wagner A, Pinborg LH.  Reproducibility of [(123)I]PE2I binding to dopamine transporters with SPECT. Eur J Nucl Med Mol Imaging 2007;34:101-9.

Lærebøger, andre oversigtsartikler og ledere
Innis RB, Cunningham VJ, Delforge J, Fujita M,  Gjedde A, Gunn RN, Holden J, Houle S, Huang S-C, Ichise M, Iida H, Ito H, Kimura Y, Koeppe RA, Knudsen GM, Knuuti J, Lammertsma AA, Laruelle M, Logan J, Maguire RP, Mintun MA, Morris ED, Parsey R, Price JC, Slifstein M, Sossi V, Suhara T, Votaw JR, Wong DF, Carson RE. Consensus nomenclature for in vivo imaging of reversibly-binding radioligands.  J Cereb Blood Flow Metab, 2007:27;1533-9.
Knudsen GM. Emotioner og hjernens transmittersystemer. In: Jensen TW, Skov M, eds. Følelser og kognition. København: Museum Tusculanums Forlag, 2007:113-25.
Paulson OB, Balslev D, Gerlach C. Hvad er PET og fMRI? In: Jensen TW, Skov M, eds. Følelser og kognition. København: Museum Tusculanums Forlag, 2007:37-53.
Paulson OB, Parving HH. Niels A. Lassens banebrydende forskning. Ugeskr Laeger 2007;169:2899.
Ramsøy T, Balslev D, Paulson OB. Methods for observing the living brain. In: Baars BJ, Gage NM, eds. Cognition, brain and consciousness. Amsterdam: Academic Press, 2007:477-511.
Sigurdsson ST, Strandgaard S. Blood pressure lowering in acute ischaemic stroke: an update on the role of angiotensin receptor blockers. J Hypertens 2007;25:743-5.
Skov M, Stjernfelt F, Paulson OB. Language and the brain’s mental cinema. In: Grundtvig B, McLaughlin M, Petersen LW, eds. Image, eye and art in Calvino. London: Modern Humanities Research Association and Maney Publishing, 2007:185-99.
Strandgaard S, Paulson OB. Hypertension and brain. In: Anand MP, Nadkar MY, eds. Hypertension. India: IJCP Group of Publications, 2007;137-42.
Strandgaard S, Paulson OB. Management of hypertension with cerebrovascular disease. In: Anand MP, Nadkar MY, eds. Hypertension. India: IJCP Group of Publications, 2007;268-72.
 
 

2006

Disputatser og phd-afhandlinger
Høgh-Rasmussen E. PhD-afhandling: Tomographic reconstruction using anatomy and regularization. København: Eget forlag 2006:1-184. Forsvaret d. 17. februar 2006 ved Danmarks Tekniske Universitet.
Søndergaard K. PhD-afhandling: Synthesis, binding studies and PET studies of 2-substituted apomorphines. København: HCØ Tryk 2006:1-88. Forsvaret d. 26. januar 2006 ved Danmarks Farmaceutiske Universitet

Originale publikationer i peer-reviewed journals
Andersen PB, Blinkenberg M, Lassen U, Kosteljanetz M, Wagner A, Poulsen HS, Sørensen PS, Paulson OB. A prospective PET study of patients with glioblastoma multiforme. Acta Neurol Scand 2006;116:412-8.
Balslev D, Nielsen FAa, Lund TE, Law I, Paulson OB. Similar brain networks for detecting visuo-motor and visuo-proprioceptive synchrony. Neuroimage 2006;31:308-12.
Frøkjær VG, Strauss GI, Mehlsen J, Knudsen GM, Rasmussen V, Larsen FS. Autonomic dysfunction and impaired cerebral autoregulation in cirrhosis. Clin Auton Res 2006;16:208-16.
Gerlach C, Law I, Paulson OB. Shape configuration and category-specificity. Neuropsychologia 2006;44:1247-60.
Glenthoj BY, Mackeprang T, Svarer C, Rasmussen H, Pinborg LH, Friberg L, Baaré W, Hemmingsen R, Videbaek C. Frontal dopamine D2/3 receptor binding in drug-naive first-episode schizophrenic patients correlates with positive psychotic symptoms and gender. Biol Psychiatry 2006;60:621-9.
Husum H, Aznar S, Høyer-Hansen S, Larsen MH, Mikkelsen JD, Møller A, Mathé AA, Wörtwein G. Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IR fiber lengths in the dorsal hippocampus of the aged flinders sensitive line “depressed” rat: Implications for the pathophysiology of depression? J Neuroscience Res 2006;84:1292-1302.
Kondziella D, Brenner E, Eyjolfsson EM, Markinhuhta KR, Carlsson ML, Sonnewald U. Glial-neuronal interactions are impaired in the schizophrenia model of repeated MK801 exposure. Neuropsychopharmacology 2006;31(9):1880-7.
Kornum BR, Weikop P, Møller A, Ronn LCB, Knudsen GM, Aznar S. Serotonin depletion results in a decrease of the neuronal activation caused by rivastigmine in the rat hippocampus. Brain Research 2006;1073-1074:262-8.
Kornum BR, Licht CL, Weikop P, Knudsen GM, Aznar S. Central serotonin depletion affects rat brain areas differently: A qualitative and quantitative comparison between different treatment schemes. Neurosci Lett 2006;392:129-34.
Lindberg C, Koefoed P, Hansen ES, Bolwig TG, Rehfeld JF, Mellerup E, Jorgensen OS, Kessing LV, Werge T, Haugbol S, Wang AG, Woldbye DP. No association between the -399 C > T polymorphism of the neuropeptide Y gene and schizophrenia, unipolar depression or panic disorder in a Danish population. Acta Psychiatr Scand 2006;113:54-8.
Linde R, Hasselbalch SG, Topp S, Paulson OB, Madsen PL. Global cerebral blood flow and metabolism during acute hyperketonemia in the awake and anesthetized rat. J Cereb Blood Flow Metab 2006;26:170-80.
Mathiesen HK, Jonsson A, Tscherning T, Hanson LG, Andresen J, Blinkenberg M, Paulson OB, Sorensen PS. Correlation of global N-acetyl aspartate with cognitive impairment in multiple sclerosis. Arch Neurol 2006;63:533-6
Nielsen K, Rostrup E, Frederiksen JL, Knudsen S, Mathiesen HK, Hanson LG, Paulson OB. Magnetic resonance imaging at 3.0 Tesla detects more lesions in acute optic neuritis than at 1.5 Tesla. Invest Radiol 2006;41:76-82.
Nielsen K, Brask D, Knudsen GM, Aznar S. Immunodetection of the serotonin transporter protein is a more valid marker for serotonergic fibers than serotonin. Synapse 2006;59:270-6.
Scheuer KH, Nielsen JE, Krabbe K, Paulson OB, Law I. Motor activation in SPG4 linked hereditary spastic paraplegia. J Neurol Sci 2006;244:31-9.

Lærebøger, andre oversigtsartikler og ledere
Hasselbalch SG, Knudsen GM. Imaging of neurotransmitter systems in dementia. In: Herholz K, Perani D, Morris C, eds. The Dementias. Early Diagnosis and Evaluation. New York: Taylor and Francis Group 2006:253-77.
 
 

2005

Disputatser og phd-afhandlinger
Balslev D. Ph.d.-afhandling: Proprioception - an obstacle for motor control in conditions with a visuoproprioceptive conflict. København: Eget forlag 2005:1-73. Forsvaret d. 12. september 2005 ved Københavns Universitet, Det Sundhedsvidenskabelige Fakultet.

Originale publikationer i peer-reviewed journals
Adams KH, Hansen ES, Pinborg LH, Hasselbalch SG, Svarer C, Holm S, Bolwig TG, Knudsen GM. Patients with obsessive-compulsive disorder have increased 5-HT2A receptor binding in the caudate nuclei. Int J Neuropsychopharmacol 2005;8:391-401
Aznar S, Kostova V, Christiansen SH, Knudsen GM. Alpha7 nicotinic receptor subunit is present on serotonin neurons projecting to hippocampus and septum. Synapse 2005;55(3):196-200
Balslev D, Nielsen FÅ, Paulson OB, Law I. Right temporoparietal cortex activation during visuo-proprioceptive conflict. Cereb Cortex 2005;15:166-9.
Dethloff T, Knudsen GM, Hansen BA, Larsen FS. Effects of porta-systemic shunting and ammonia infusion on cerebral blood flow autoregulation in the rat. Neurocrit Care 2005;3(1):86-90.
Fenger MM, Gade A, Adams KH, Hansen ES, Bolwig TG, Knudsen GM. Cognitive deficits in obsessive-compulsive disorder on tests of frontal lobe functions. Nord J Psychiatry 2005;59:39-44.
Garde E, Lykke Mortensen E, Rostrup E, Paulson OB. Decline in intelligence is associated with progression in white matter hyperintensity volume. J Neurol Neurosurg Psychiatry 2005;76:1289-91.
Gerlach C, Marstrand L, Habekost T, Gade A. A case of impaired shape integration: Implications for models of visual object processing. Visual Cognition 2005;12(8):1409-43.
Jelsing J, Rostrup E, Markenroth K, Paulson OB, Gundersen HJG, Hemmingsen R, Pakkenberg B. Assessment of in vivo MR imaging compared to physical sections in vitro - A quantitative study of brain volumes using stereology. NeuroImage 2005;26:57-65.
Kristiansen H, Elfving B, Plenge P, Pinborg LH, Gillings N, Knudsen GM. Binding characteristics of the 5-HT2A receptor antagonists altanserin and MDL100907. Synapse 2005 Dec 15;58(4):249-57.
Mathiesen HK, Tscherning T, Sørensen PS, Larsson HBW, Rostrup E, Paulson OB, Hanson LG. Multi-slice echo-planar spectroscopic MR imaging provides both global and local metabolite measures in multiple sclerosis. Magn Reson Med 2005;53:750-9.
Nielsen FÅ, Balslev D, Hansen LK. Mining the posterior cingulate: Segregation between memory and pain components. Neuroimage 2005;27:520-32.
Pinborg LH, Ziebell M, Frøkjær VG, de Nijs R, Svarer C, Haugbøl S, Yndgaard S, Knudsen GM. Quantification of 123I-PE2I binding to dopamine transporter with SPECT after bolus and bolus/infusion. J Nucl Med 2005;46:1119-27.
Pryds A, Tønnesen J, Knudsen GM, Greisen G. Cerebral autoregulation in a rat pup model. Pediatr Res. 2005;57:294-8.
Rostrup E, Knudsen GM, Law I, Holm S, Larsson HB, Paulson OB. The relationship between cerebral blood flow and volume in humans. Neuroimage 2005;24:1-11
Rostrup E, Larsson HBW, Born AP, Knudsen GM, Paulson OB. Changes in BOLD and ADC weighted imaging in acute hypoxia during sea-level and altitude adapted states. Neuroimage 2005;28:947-55.
Scheuer KH, Nielsen JE, Krabbe K, Simonsen C, Koefoed P, Sorensen SA, Gade A, Paulson OB, Law I. Reduced regional cerebral blood flow in SPG4-linked hereditary spastic paraplegia. J Neurol Sci 2005;15;235:23-32.
Svarer C, Madsen K, Hasselbalch SG, Pinborg LH, Haugbøl S, Frøkjær VG, Holm S, Paulson OB, Knudsen GM. MR-based automatic delineation of volumes of interest in human brain PET-images using  probability maps. NeuroImage 2005;24:969-79
Søndergaard K, Kristensen JL, Palner M, Gillings N, Knudsen GM, Roth BL, Begtrup M. Synthesis and binding studies of 2-arylapomorphines. Org Biomol Chem 2005;3(22):4077-81.
Tønnesen J, Pryds A, Larsen EH, Paulson OB, Hauerberg J, Knudsen GM. Laser Doppler flowmetry is valid for measurement of cerebral blood flow autoregulation lower limit in rats. J Exp Physiol 2005;90:349-55.
Søndergaard K, Kristensen JL, Gillings N, Begtrup M. Synthesis of (R)-(-)-2-fluoronorapomorphine - A precursor for the synthesis of (R)-(-)-2-fluoro-N[11C}propylnorapomorphine for evaluation as a dopamine D2 agonist ligand for PET investigations. Eur J Org Chem 2005;20:4428-33.
Vogel A, Hasselbalch SG, Gade A, Ziebell M, Waldemar G. Cognitive and functional neuroimaging correlates for anosognosia in Mild Cognitive Impairment and Alzheimer’s disease. Int J Geriatr Psychiatry 2005;20:238-46.

Lærebøger, andre oversigtsartikler og ledere
Knudsen GM, Paulson OB, Petersen P. Neurologiske sygdomme. I: Hansen NE, Haunsø S, de Muckadell OBS, eds. Medicinsk Kompendiums Lommebog, 3. udgave. København: Nyt Nordisk Forlag Arnold Busck A/S, 2005:526-68.
 
 

2004

Disputatser og phd-afhandlinger
Adams KH. Ph.d.-afhandling 2004: The in vivo brain distribution of serotonin 5-HT2A receptors in healthy subjects and in patients with obsessive-compulsive disorder: a positron emission study with [18F]-altanserin.
Scheuer KH. Ph.d.-afhandling 2004: Assessment of cerebral involvement in SPG4 linked hereditary spastic paraplegia.

Originale publikationer i peer-reviewed journals
Adams KH, Pinborg LH, Svarer C, Hasselbalch SG, Holm S, Mortensen EL, Haugbøl S, Madsen K, Frokjaer V, Martiny L, Paulson OB, Knudsen GM: A database of [18F]-altanserin binding to 5-HT2A receptors in normal volunteers: normative data and relationship to physiological, and demographic variables. NeuroImage 2004;21:1105-13
Aznar S, Qian ZX, Knudsen GM. Non-serotonergic dorsal and median raphe projection on parvalbumin- and calbindin-containing neurons in hippocampus and septum. Neuroscience 2004;124(3):573-81.
Balslev D, Christensen LOD, Lee J-H, Law I,  Paulson OB, Miall RC. Enhanced accuracy in novel mirror drawing after repetitive transcranial magnetic stimulation-induced proprioceptive deafferentation. J Neurosci 2004;24:9698-9702.
Cohen ER, Rostrup E Sidaros K Lund TE, PaulsonOB, Ugurbil K, Kim S-G. Hypercapnic normalization of BOLD fMRI: comparison across field strengths and pulse sequences. Neuroimage 2004;23:613-24.
Fumagalli M, Mosca F, Knudsen GM, Greisen G. Transient hyperoxia and residual cerebrovascular effects in the newborn rat. Pediatr Res 2004;55(3):380-4.
Fumagalli M, Mosca F, Knudsen GM, Greisen G.  A newborn rat model for the study of cerebral hemodynamics by near-infrared spectroscopy and laser-Doppler flowmetry in the immature brain. Biol Neonate 2004;85(2):112-20.
Gerlach C, Law I, Paulson OB. Structural similarity and category-specificity: a refined account. Neuropsychol 2004;42:1543-53.
Humphreys GW, Kylingsbæk S, Watson DG, Olivers CNL, Law I, Paulson OB. Parieto-occipital areas involved in efficient filtering in search: A time course analysis of visual marking using behavioural and functional imaging procedures. Q J Exp Psychol A 2004;57:610-35.
Knudsen GM, Karlsborg M, Thomsen G, Krabbe K, Regeur L, Nygaard T, Videbæk C, Werdeling L. Imaging of dopamine transporters and D2 receptors in patients with Parkinsons disease and multiple system atrophy. Eur J Nuclear Med Mol Imaging 2004;12:1631-8.
Liptrot M, Adams KH, Martiny L, Pinborg LH, Lonsdale MN, Olsen NV, Holm S, Svarer C, Knudsen GM: Cluster analysis in kinetic modelling of the brain: a non-invasive alternative to arterial sampling. NeuroImage 2004;21:483-493.
Madsen J, Elfving B, Andersen K, Martiny L, Knudsen GM. Gas phase production of [11C]methyl iodide-d3. Synthesis and biological evaluation of S-[N-methyl-11C]citalopram and deuterated analogues. J Label Compd Radiopharm 2004;47:335-48.
Møller K, Qvist T, Tofteng F, Sahl C, Sønderkær S, Dethloff T, Knudsen GM, Larsen FS. Cerebral blood flow and metabolism during infusion of norepinephrine and propofol in patients with bacterial meningitis. Stroke 2004;35:1333-9.
Nielsen FA, Hansen LK, Balslev D. Mining for associations between text and brain activation in a functional neuroimaging database. Neuroinformatics 2004;4:369-80.
Nielsen JE, Johnsen B, Koefoed P, Scheuer KH, Grønbech-Jensen M, Law I, Krabbe K, Nørremølle A, Eiberg H, Søndergård H, Dam M, Rehfeld JF, Krarup C, Paulson OB, Hasholt L, Sørensen SA. Hereditary spastic paraplegia with cerebellar ataxia: a complex phenotype associated with a new SPG4 gene mutation. Eur J Neurol 2004;11:817-24.
Pinborg LH, Adams KH, Yndgaard S, Hasselbalch SG, Holm S, Kristiansen H, Paulson OB. Knudsen GM. [18F]altanserin binding to human 5HT2A receptors is unaltered after citalopram and pindolol challenge. J Cereb Blood Flow Metab 2004;24:1037-45.
Quarantelli M, Berkouk K, Prinster A, Landeau B, Svarer C, Balkay L, Alfano B, Brunetti A, Baron JC, Salvatore M. Integrated Software for the Analysis of Brain PET/SPECT Studies with Partial-Volume-Effect Correction. J Nucl Med 2004;45:192-201.
Sveen ML, Knudsen GM, Aznar S. No effect of MDMA (ecstasy) on cell death and 5-HT(2A) receptor density in organotypic rat hippocampal cultures. Neurosci Lett. 2004;362:6-9.

Lærebøger, andre oversigtsartikler og ledere
Eskesen V, Paulson OB. Bevidsthedssvækkelse og bevidstløshed. I: Paulson OB, Gjerris F, Sørensen PS (eds). Klinisk neurologi og neurokirurgi. 4. udg. København: FADL, 2004:197-214.
Knudsen GM, Paulson OB. Hjernens fysiologi. I: Paulson OB, Gjerris F, Sørensen PS (eds). Klinisk neurologi og neurokirurgi. 4. udg. København: FADL, 2004:239-54.
Knudsen GM, Sørensen PSS. Neurologiske manifestationer ved systemiske sygdomme. I: Paulson OB, Gjerris F, Sørensen PS (eds). Klinisk neurologi og neurokirurgi. København: FADL’s Forlag. 4. udg. 2004:609-28.
Knudsen GM, Rostrup E, Hasselbalch SG. Quantitative PET for assessment of cerebral blood flow and glucose consumption under varying physiological conditions. Int Congress Series 2004;1265:189-200
Paulson OB. Mobiltelefoni - kan det påvirke blod-hjerne-barrieren? Ugeskr Læger 2004;13:1209-11.
Paulson OB, Boysen G, Krarup C, Knudsen GM, Sørensen PS. Neurologi. I: Hansen NE, Haunsø S, Schaffalitzky de Muckadell OB, eds. Medicinsk Kompendium, 16. udgave. København: Nyt Nordisk Forlag, 2004:2505-2703.
Paulson OB, Gjerris F. Introduktion til klinisk neurologisk undersøgelse. I: Paulson OB, Gjerris F, Sørensen PS (eds). Klinisk neurologi og neurokirurgi. 4. udg. København: FADL, 2004:21-26.
Paulson OB, Gjerris F. Det motoriske system. I: Paulson OB, Gjerris F, Sørensen PS (eds). Klinisk neurologi og neurokirurgi. 4. udg. København: FADL, 2004:69-112.
Paulson OB, Gjerris F, Sørensen PS (eds). Klinisk neurologi og neurokirurgi. 4. udg. København: FADL, 2004:1-648.
Sørensen PSS, Paulson OB. Det sensoriske system. I: Paulson OB, Gjerris F, Sørensen PS (eds). Klinisk neurologi og neurokirurgi. 4. udg. København: FADL, 2004:55-68.
Sørensen PS, Paulson OB. Intoksikationer og ernæringsdeficit. I: Paulson OB, Gjerris F, Sørensen PS (eds). Klinisk neurologi og neurokirurgi. 4. udg. København: FADL, 2004:537-58.
Vorstrup S, Paulson OB. Defekter i den neuromuskulære transmission. I: Paulson OB, Gjerris F, Sørensen PS (eds). Klinisk neurologi og neurokirurgi. 4. udg. København: FADL, 2004:585-92.
Willendrup P, Pinborg LH, Hasselbalch SG, Adams KH, Stahr K, Knudsen GM, Svarer C: Assessment of the precision in co-registration of structural MR-images and PET-images with localized binding. Int Congress Series 2004;1265:275-80
 
 

2003

Disputatser og phd-afhandlinger
Elfving B. Characterization of serotonin transporter ligands in relation to emission tomography (ph.d-afhandling). København: Eget forlag; 2003:1-102. Forsvaret den 10. januar 2003 ved Københavns Universitet, Det Sundhedsvidenskabelige Fakultet.
Hasselbalch SG. Quantitation of brain metabolism in humans usings PET-FDG: levels and limitations (disputats). København: Eget forlag; 2003:1-51. Forsvaret den 25. april 2003 ved Københavns Universitet, Det Sundhedsvidenskabelige Fakultet.
Ma XD. Effect of graded hyperventilation on cerebral blood flow, autoregulation, and metabolism in experimental subarachnoid hemorrhage and acute intracranial hypertension (ph.d-afhandling). København: Eget forlag; 2003:1-139. Forsvaret den 30. juni 2003 ved Københavns Universitet, Det Sundhedsvidenskabelige Fakultet.
Madsen J. Development of new PET and SPECT ligands for visualization of the serotonin transporter in the brain (ph.d-afhandling). København: Eget forlag; 2003:1-66. Forsvaret den 8. maj 2003 ved Danmarks Farmaceutiske Universitet.

Originale publikationer i peer-reviewed journals
Andersen PB, Krabbe K, Leffers AM, Schmiegelow M, Holm S, Laursen H, Müller JR, Paulson OB. Cerebral glucose metabolism in long-term survivors of childhood primary brain tumors treated with surgery and radiotherapy. J Neurooncol 2003;63:305-13.
Aznar S, Qian Z, Shah R, Rahbek B, Knudsen GM: The 5-HT1A serotonin receptor is located on calbindin- and parvalbumin-containing neurons in the rat brain. Brain Res 2003;959:58-67.
Bay-Hansen R, Ma XD, Hauerberg J, Larsen EH, Juhler M. Effects of cerebrospinal fluid acidity on cerebral blood flow and autoregulation in rats. J Neurosurg Anesth 2003;15:110-8.
Elfving B, Bjørnholm B, Knudsen GM: Interference of anaesthetics with radioligand binding in neuroreceptor studies. Eur J Nucl Med 2003;30:912-5.
Madsen J, Marachtsaki P, Davoodpour P, Bergström M, Långström B, Andersen K, Thomsen C, Martiny L, Knudsen GM. Synthesis and biological evaluation of novel carbon-11-labelled analogues of citalopram as potential radioligands for the serotonin transporter. Bioorg Med Chem 2003;11:3447-56.
Pedersen TF, Paulson OB, Nielsen AH, Strandgaard S. Effect of nephrectomy and captopril on autoregulation of cerebral blood flow in rats. Am J Physiol Heart Circ Physiol 2003;285:1097-104.
Pinborg LH, Adams KH, Svarer C, Holm S, Hasselbalch SG, Haugbøl S, Madsen J, Knudsen GM. Quantification of 5-HT2A receptors in the human brain using [18F]Altanserin-PET and the bolus/infusion approach. J Cereb Blood Flow Metab 2003;23:985-96.
Strauss GI, Møller K, Larsen FS, Kondrup J, Knudsen GM: Cerebral glucose and oxygen metabolism in patients with fulminant hepatic failure. Liver Transpl. 2003;9:1244-52.

Lærebøger, andre oversigtsartikler og ledere
Højgaard L, Eigtved A, Paulson OB. Brain metastases, intracranial lymphomas, and nongliomatous tumors. In: Von Schulthess GK, ed. Clinical molecular anatomic imaging. Philadelphia: Lippincott Williams & Wilkins, 2003:169-74.
Hasselbalch SG. Neuroreceptor imaging with positron emission tomography in dementia. Dementia 2003;4:2-7.
 
 

2002

Doctoral and PhD theses
Charlotte Videbæk, cand.med., dr.med. Single photon emission tomography for neuroreceptor studies: Methodological considerations
Trine Fischer Pedersen, cand.scient, PhD. Modulation of cerebral blood flow and its autoregulation by the renin-angiotensin system, in nephrectomized rats

Originale publikationer i peer-reviewed journals
Abildstrom H, Hogh P, Sperling B, Moller JT, Yndgaard S, Rasmussen LS. Cerebral blood flow and cognitive dysfunction after coronary surgery. Ann Thorac Surg 2002;73:1174-8
Balslev D, Nielsen FAA, Frutiger SA, Sidtis JJ, Christiansen TB, Svarer C, Strother SC, Rottenberg DA, Hansen LK, Paulson OB, Law I. Cluster analysis of activity-time series in motor learning. Human Brain Mapping 2002;15:135-45
Bay-Hansen R, Elfving B, Greisen G. Use of near infrared spectroscopy for estimation of peripheral venous saturation in newborns: comparison with co-oximetry of central venous blood. Biol Neonate 2002;82:1-8
Born A P, Law I, Lund T E, Rostrup E, Hanson L G P, Wildschiødtz G, Lou H C, Paulson O B. Cortical deactivation induced by visual stimulation in Human Slow-Wave Sleep. Neuroimage 2002;17:1325-35
Bundesen C, Larsen A., Kyllingsbæk, S, Paulson O B, Law I. Attentional effects in early visual pathways: A whole-brain PET study. Exp Brain Res 2002;147:394-406
Elfving B, Bjørnholm B, Knudsen GM. Predosing with the unlabeled inactive enantiomer as a tool for improvement of the PET signal. Synapse 2002;46:125-127
Gerlach C, Law I, Gade A, Paulson OB. The role of action knowledge in the comprehension of artefacts - A PET study. NeuroImage 2002;15:143-52
Gerlach C, Aaside CT, Humphreys GW, Gade A, Paulson OB, Law I. Brain activity related to integrative processes in visual object recognition: bottom-up integration and the modulatory influence of stored knowledge. Neuropsychologia 2002;40:1254-67
Gerlach C, Law I, Paulson OB. When action turns into words. Activation of motor-based knowledge during categorization of manipulable objects. J Cogn Neuroscience 2002;14:1230-9.
Hansen ES, Hasselbalch S, Law I, Bolwig TG. The caudate nucleus in obsessive-compulsive disorder. Reduced metabolism following treatment with paroxetine: a PET study. Int J Neuropsychopharm 2002;5:1-10
Hesse B, Mehlsen J, Boesen F, Schmidt JF, Andersen EB, Waldemar G, Andersen AR, Paulson OB, Vorstrup S. Regulation of cerebral blood flow in patients with autonomic dysfunction and severe postural hypotension. Clin Physiol & Func Im 2002;22:241-7
Kjær T, Law I, Wildschiødtz G, Paulson, O B, Madsen P L. Regional cerebral blood flow during light sleep - A H215O-PET study. J Sleep Res 2002;11:201-7
Møller K, Paulson OB, Hornbein TF, Colier W, Roach R, Knudsen GM. Unchanged cerebral blood flow and oxidative metabolism after acclimatization to high altitude. J Cereb Blood Flow Metabol 2002; 22:118-26
Møller K, Strauss GI, Thomsen G, Larsen FS, Holm S, Sperling BK, Skinhøj P, Knudsen GM. Cerebral blood flow, oxidative metabolism, and cerebrovascular carbon dioxide reactivity in patients with acute bacterial meningitis. Acta Anaesthesiol Scand 2002;46:567-78
Møller K, Strauss GI, Qvist J, Fonsmark L, Knudsen GM, Larsen FS, Krabbe KS, Skinhøj P, Pedersen BK. Cerebral blood flow and oxidative metabolism during human endotoxemia. J Cereb Blood Flow Metab 2002;22:1262-70
Pedersen TF, Nielsen AH, Strandgaard S, Paulson OB. Nephrectomy and peritoneal dialysis eliminates circulating renin and controls uraemia in the rat. JRAAS 2002;3:130-4
Pinborg LH, Videbæk C, Svarer C, Yndgaard S, Paulson OB, Knudsen GM. Quantification of [123I]PE2I binding to dopamine transporters with SPET.  Eur J Nucl Med 2002;29:623-31
Rabiner EA, Messa C, Sargent PA, Husted-Kjaer K, Montgomery A, Lawrence AD, Bench CJ, Gunn RN, Cowen P, Grasby PM. A database of [11C]WAY-100635 binding to 5-HT1A receptors in normal male volunteers: Normative data and relationship to methodological, demographic, physiological, and behavioral variables. Neuroimage 2002;15:620-32
Rasmussen LS, Sperling B, Abildstrom HH, Moller JT. Neuron loss after coronary artery bypass detected by SPECT estimation of benzodiazepine receptors.Ann Thorac Surg 2002;74:1576-80
Rostrup E, Law I, Pott F, Ide K, Knudsen G M. Cerebral hemodynamics measured with simultaneous PET and near-infrared spectroscopy in humans. Brain Res 2002;954:183-93
Schmalbruch IK, Linde R, Paulson OB, Madsen PL. Activation-induced resetting of cerebral metabolism and flow is abolished by ?-adrenergic blockade with propranolol. Stroke 2002;33:251-5
Springborg JB, Ma X, Rochat P, Knudsen GM, Amtorp A, Paulson OB,  Juhler M, Olsen NV. A single subcutaneous bolus of erythropoietin normalizes cerebral blood flow autoregulation after subarachnoid hemorrhage in rats. Br J Pharmacol 2002;135:823-9

Lærebøger, andre oversigtsartikler og ledere
Knudsen GM. Funktionel billeddannelse af receptorforandringer ved parkinsonisme: Emissionstomografiske metoder til hjæp i diagnostikken. Ugeskr Laeger 2002;22:2259-62
Knudsen GM, Svarer C. Neuroreceptor imaging: Considerations for design, data analysis, and interpretation. In: Senda M, Kimura Y, Herscovitch P (eds). Brain imaging using PET. San Diego: Academic Press, 2002:p.23-6.
Law I, Roach RC, Olsen NV, Holm S, Nowak M, Hornbein TF, Paulson  OB. Oxygen delivery to the brain during behavioral activation at acute normobaric hypoxemia. In: Tomita M, Kanno I, and Hamel E, eds. Brain activation and CBF control. Excerpta Medica. International Congress Series nr 1235, Elsevier Science. 2002, 87 – 98.
Paulson OB, Law I. Hemodynamic and metabolic features of cerebral activation. In: Tomita M, Kanno I, and Hamel E, eds. Brain activation and CBF control. Amsterdam: Elsevier, 2002;205-12.
Paulson OB, Born AP, Bundesen C, Gade A, Gerlach C, Hansen LK, Holm S, Jensen M, Kyllingsbæk S, Larsen A, Law I, Rostrup E, Svarer C. Den arbejdende hjerne - hvordan kan den se ud? Ugeskr Læg 2002;164:2267-75
Paulson OB. Blood-brain barrier, brain metabolism and cerebral blood flow. Eur Neuropsychopharmacol 2002;12:495-501
Willendrup P, Svarer C, Hanson LG, Paulson OB. A simple approach to combined inhomogeneity correction and tissue segmentation of MR MPRAGE images. In: Senda M, Kimura Y, Herscovitch P (eds). Brain imaging using PET. San Diego: Academic Press, 2002:p.159-62.
 
 

2001

Disputatser og ph.d.-afhandlinger
Møller K. Ph.d.-afhandling 2001: Cerebral blood flow autoregulation in patients with acute bacterial meningitis
Høgh P. Ph.d.-afhandling 2001: Apolipoprotein E (APOE) – genotypens betydning for patofysiologi og sygdomsforløb ved Alzheimer’s sygdom og ved dissemineret sklerose

Originale publikationer i peer-reviewed journals
Aznar S, Knudsen GM: Serotonin induces decrease of 5-HT1A immunoreactivity in organotypic hippocampal cultures. NeuroReport 2001;12:3909-12.
Bech-Azeddine R, Waldemar G, Knudsen GM, Høgh P, Bruhn P, Wildschiødtz G, Gjerris F, Paulson OB, Juhler M. Idiopatic normal-pressure hydrocephalus: evaluation and findings in a multidisciplinary memory clinic. Eur J Neurol 2001;8:601-11.
Blinkenberg M, Rune K, Jensen CV, Ravnborg MH, Kyllingsbæk S, Holm S, Paulson OB, Sørensen PS. Reduceret cerebralt stofskifte korrelerer med MRI-forandringer og kognitiv dysfunktion hos patienter med dissemineret sklerose. Ugeskr Læg 2001;163:3788-92.
Elfving B, Bjørnholm B, Ebert B, Knudsen GM: Binding characteristics of selective serotonin reuptake inhibitors with relation to emission tomography studies. Synapse 2001;41:203-11.
Estrup TM, Paulson OB, Strandgaard. No effect of angiotensin II AT2 receptor antagonist PD123319 on cerebral blood flow autoregulation. JRAAS 2001;2:188-92.
Gerlach C. Structural similarity causes different category-effects depending on task characteristics. Neuropsychologia 2001;39:895-900.
Gruhn N, Larsen FS, Boesgaard S, Knudsen GM, Mortensen SA, Thomsen G, Aldershvile J. Cerebral blood flow in patients with chronic heart failure before and after heart transplantation. Stroke 2001;32: 2530-3.
Hasselbalch SG, Holm S, Pedersen HS, Svarer C, Knudsen GM, Madsen PL, Paulson OB. The 18F-fluorodeoxyglucose lumped constant determined in human brain from extraction fractions of 18F-fluorodeoxyglucose and glucose. J Cereb Blood Flow Metab 2001;21:995-1002.
Hasselbalch SG, Knudsen GM, Capaldo B, Postiglione A, Paulson OB. Blood-brain barrier transport and brain metabolism of glucose during acute hyperglycemia in humans. J Clin Endocrinol Metab 2001;86; 1986-90.
Høgh P, Knudsen GM, Kjaer KH, Jørgensen OS, Paulson OB, Waldemar G. SPECT and apolipoprotein E in Alzheimer’s disease: Impact of the epsilon-4 allele on regional cerebral blood flow. J Geriatr Psychiatry Neurol 2001;14:42-51.
Law I, Jensen M, Holm S, Nickles RJ, Paulson OB. Using 10CO2 for single subject characterization of the stimulus frequency dependence in visual cortex: A novel positron emission tomography tracer for human brain mapping. J Cereb Blood Flow Metab 2001;21:1003-12.
Pinborg LH, Videbæk C, Hasselbalch SG, Sørensen SA, Wagner A, Paulson OB, Knudsen GM. Benzodiazepine receptor quantification in Huntington’s disease with [123I]iomazenil and SPECT. J Neurol Neurosurg Psychiatry 2001;70:657-61.
Schreiber K, Sorensen PS, Koch-Henriksen N, Wagner A, Blinkenberg M, Svarer C, Petersen HC. Correlations of brain MRI parameters to disability in multiple sclerosis. Acta Neurol Scand 2001;104:24-30.
Strauss GI, Møller K, Holm S, Sperling B, Knudsen GM, Larsen FS. Transcranial doppler sonography and internal jugular bulb saturation during hyperventilation in patients with fulminant hepatic failure. Liver Transpl 2001;7:352-8.
Strauss GI, Knudsen GM, Kondrup , Møller K, Larsen FS. Cerebral metabolism of ammonia and amino  acids in patients with fulminant hepatic failure. Gastroenterology 2001;121:1109-19.
Strauss GI, Christiansen M, Møller K, Clemmesen JO, Larsen FS, Knudsen GM: S-100b and neuron-specific enolase as markers of cerebral dysfunction in patients with fulminant hepatic failure. Liver Transpl 2001;7:964-70.
Strauss GI, Edvinsson L, Larsen FS, Møller K, Knudsen GM: Circulating levels of neuropeptides (CGRP, VIP, NPY) in patients with fulminant hepatic failure. Neuropeptides 2001;35:174-80.
Sundgreen C, Larsen FS, Herzog TM, Knudsen GM, Boesgaard S, Aldershvile J. Autoregulation of cerebral blood flow in patients resuscitated from cardiac arrest. Stroke 2001;32:128-32.
Videbæk C, Toska K, Friberg L, Holm S, Angelo HR, Knudsen GM. In vivo measurement of haloperidol affinity to dopamine D2/D3 receptors by [123I]IBZM and single photon emission computed tomography. J Cereb Blood Flow Metab 2001;21:92-7.

Tekstbøger, andre oversigtsartikler og ledere
Strandgaard S, Paulson OB. Hypertension and brain. In: Anand MP, Billimoria AR, eds. Hypertension. An International Monograph 2001. India: IJCP Group, 2001. p. 138-42.
Strandgaard S, Paulson OB. Management of hypertension with cerebrovascular disease. In: Anand MP, Billimoria AR, eds. Hypertension. An International Monograph 2001. India: IJCP Group, 2001. p. 271-3.
 
 

2000

Disputatser og ph.d.-afhandlinger
Rasmus Linde. Ph.d.-afhandling 2000: Cerebral blood flow and metabolism during acute hyperketonemia.
Christian Gerlach. Ph.d.-afhandling 2000: The functional organization of knowledge and its implementation in the brain.

Originale publikationer i peer-reviewed journals
Blinkenberg M, Rune K, Jensen CV, Ravnborg M, Kyllingsbæk S, Holm S, Paulson OB, Sørensen PS. Cortical cerebral metabolism correlates with MRI lesion load and cognitive dysfunction in MS. Neurology 2000;54:558-64.
Gerlach C, Law I, Gade A, Paulson OB. Categorization and category effects in normal object recognition. A PET Study. Neuropsychologia 2000;38:1693-1703.
Hanson LG,  Schaumburg K,  Paulson OB. Reconstruction strategy for echo planar spectroscopy and its application to partially undersampled imaging. Magn Reson Med 2000;44:412-7.
Hugdahl K, Law I,Kyllingsbæk S, Brønnick K, Gade A, Paulson OB. Effects of attention on dichotic listening: An 15O-PET study. Hum Brain Mapping 2000;10:87-97.
Høgh P, Oturai A, Schreiber K, Blinkenberg M, Jørgensen OS, Ryder L, Paulson OB, Sørensen PS, Knudsen GM. Apolipoprotein E and multiple sclerosis: impact of the epsilon-4 allele on susceptibility, clinical type and progression rate. Multiple Sclerosis 2000;6:226-30.
Iida H, Law I, Pakkenberg B, Krarup-Hansen A, Eberl S, Holm S, Hansen AK, Gundersen HJG, Thomsen C, Svarer C, Ring P, Friberg L, Paulson OB. Quantitation of regional cerebral blood flow corrected for partial volume effect using O-15 water and PET: I. Theory, error analysis, and stereologic comparison. J Cereb Blood Flow Metab 2000;20:1237-51.
Kofoed KF, Hansen PR, Holm S, Hove JD, Chen K, Jin W, Jensen M, Iida H, Hesse B, Svendsen J, Kelbæk H. Regional myocardial oxygen consumption estimated by carbon-11 acetate and positron emission tomography before and after repetitive ischemia. J Nucl Cardiol 2000;7:228-34.
Kruuse C, Jacobsen TB, Lassen LH, Thomsen LL, Hasselbalch SG, DigePetersen H, Olesen J. Dipyridamole dilates large cerebral arteries concomitant to headache induction in healthy subjects.
J Cereb Blood Flow Metab 2000;20:1372-9.
Kruuse C, Jacobsen TB, Thomsen LL, Hasselbalch SG, Frandsen EK, DigePetersen H, Olesen J.   Effects of the non-selective phosphodiesterase inhibitor pentoxifylline on regional cerebral blood flow and large arteries in healthy subjects. Eur J Neurol 2000;7:629-38.
Larsen A, Bundesen C, Kyllingsbæk S, Paulson OB, Law I. Brain activation during mental transformation of size. J Cogn Neurosci 2000;12:763-74.
Larsen FS, Strauss G, Knudsen GM, Herzog TM, Hansen BA, Secher NH. Cerebral perfusion, cardiac output, and arterial pressure in patients with fulminant hepatic failure. Crit Care Med 2000;28:996-1000.
Law I, Iida H, Holm S, Nour S, Rostrup E, Svarer C, Paulson OB. Quantitation of regional cerebral blood flow corrected for partial volume effect using O-15 water and PET: II. Normal values and gray matter blood flow response to visual activation. J Cereb Blood Flow Metab 2000;20:1252-63.
Møller K, Larsen FS, Qvist J, Wandall JH, Knudsen GM, Gjørup IE, Skinhøj P. Dependency of cerebral blood flow on mean arterial pressure in patients with acute bacterial meningitis. Crit Care Med 2000;28:1027-32.
Møller K, Høgh P, Larsen FS, Strauss GI, Skinhøj P, Sperling BK, Knudsen GM. Regional cerebral blood flow during hyperventilation in patients with acute bacterial meningitis. Clin Physiol 2000;5:399-410.
Møller K, Skinhøj P, Knudsen GM, Larsen FS: Effect of short-term hyperventilation on cerebral blood flow autoregulation in patients with acute bacterial meningitis. Stroke 2000;31:1116-22.
Nour S, Svarer C, Kristensen JKI, Paulson OB, Law I. Cerebral activation during micturition in normal men. Brain 2000;123:781-9.
Pinborg LH, Videbæk C, Knudsen GM, Swahn C-G, Halldin C, Friberg L, Paulson OB, Lassen NA. Dopamine D2 receptor quantification in extrastriatal brain regions using [123I]Epidepride with bolus/infusion. Synpase 2000;36:322-9.
Rostrup E, Law I, Blinkenberg M, Larsson HBW, Born AP, Holm S, Paulson OB. Regional differences in the CBF and BOLD responses to hypercapnia: A combined PET and fMRI study. NeuroImage 2000;11:87-97.
Sargent PA, Kjær KH, Bench CJ, Rabiner EA, Messa C, Meyer J, Gunn RN, Grasby PM, Cowen PJ. Brain serotonin1A receptor binding measured by positron emission tomography with [11C]WAY-100635: effects of depression and antidepressant treatment. Arch Gen Psychiatry 2000;57:174-80.
Videbæk C, Toska K, Scheideler MA, Paulson OB, Knudsen GM. SPECT tracer [123I]IBZM has similar affinity to dopamine D2 and D3 receptors. Synapse 2000;38:338-42.

Tekstbøger, andre oversigtsartikler og ledere
Gjedde A, Hansen SB, Knudsen GM, Paulson OB, eds. Physiological imaging of the brain with PET. San Diego: Academic Press 2000.
Iida H, Law I, Pakkenberg B, Eberl S, Paulson OB. Quantitation of regional cerebral blood flow corrected for partial volume effect using O-15 water and PET. In: Tamaki N, Tsukamoto E., Kuge Y, Katoh C. and Morita K, eds. Positron Emission Tomography in the Millennium. Elsevier Science. 2000; 245.
Knudsen GM, Paulson OB. Neurologiske og neuromuskulære sygdomme. I: Lorenzen I, Bendixen G, Hansen NE, eds. Medicinsk Kompendiums Lommebog, 2. udgave. København: Nyt Nordisk Forlag Arnold Busck A/S, 2000:496-538.
Spence JD, Paulson OB, Strandgaard S. Hypertension and stroke. In: Messerli FH, ed. The ABCs of antihypertensive therapy. New York: Lippincott Williams & Wilkins, 2000:279-96.
 
 

1999

Disputatser og ph.d.-afhandlinger
Larsen FS. Ph.d.-afhandling: High volume plasmapheresis in acute liver failure .
Schmalbruch I. Ph.d.-afhandling: A physiological and biochemical study on cerebral metabolism before, during and after physiological and amphetamine-induced activation and the effect of propranolol.

Originale publikationer i peer-reviewed journals
Blinkenberg M, Jensen CV, Holm S, Paulson OB, Sørensen PS. A longitudinal study of cerebral glucose metabolism, MRI, and disability in patients with MS. Neurology 1999;53:149-53.
Gerlach C, Law I, Gade A, Paulson OB. Perceptual differentiation and category effects in normal object recognition. A PET study. Brain 1999;122:2159-70.
Hansen LK, Larsen J, Nielsen FÅ, Strother SC, Rostrup E, Savoy R, Lange N, Sidtis J, Svarer C, Paulson OB. Generalizable patterns in neuroimaging: How many principal components? NeuroImage 1999;9:534-44.
Hasselbalch SG, Knudsen GM, Videbæk C, Pinborg LH, Schmidt JF, Holm S, Paulson OB. No effect of insulin on glucose blood-brain barrier transport and cerebral metabolism in humans.  Diabetes 1999;48:1915-21.
Herholz K, Nordberg A, Salmon E, Perani D, Kessler J, Mielke R, Halber M, Jelic V, Almkvist O, Collette F, Alberoni M, Kennedy A, Hasselbalch S, Fazio F, Heiss W. Impairment of neocortical metabolism predicts progression in Alzheimer's disease. Dementia Geriatr Cogn Disord Nov-Dec; 10(6): 494-504; 1999.
Hugdahl K, Brønnick K,Kyllingsbæk S, Law I, Gade A, Paulson OB. Brain activation during dichotic presentations of consonant-vowel and musical instrument stimuli: a 15O-PET study. Neuropsychologia 1999;37:431-40.
Høgh P, Waldemar G, Knudsen GM, Bruhn P, Mortensen H, Wildschiødtz G, Bech RA, Juhler M, Paulson OB. A multidisciplinary memory clinic in a neurological setting: diagnostic evaluation of 400 consecutive patients. Eur J Neurol 1999;6:279-88.
Kim S, Rostrup E, Larsson HBW, Ogawa S, Paulson OB. Determination of relative CMRO2 from CBF and BOLD changes: Significant increase of oxygen consumption rate during visual stimulation. Magn Reson Med 1999;41:1152-61.
Kjems U, Strother SC, Anderson J, Law I, Hansen LK. Enhancing the multivariate signal of [15O] water PET studies with a new nonlinear neuroanatomical registration algorithm. IEEE Transactions on Medical Imaging 1999;18:306-19.
Knudsen GM, Hasselbalch SG, Hertz MM, Paulson OB. High dose insulin does not increase glucose transfer across the blood-brain barrier in humans: a re-evaluation. Eur J Clin Invest 1999;29(8):687-91.
Linde R, Schmalbruch IK, Paulson OB, Madsen PL. The Kety-Schmidt technique for repeated measurements of global cerebral blood flow and metabolism in the conscious rat. Acta Physiol Scand 1999;165:395-401.
Nowak M, Olesen KS, Law I, Holm S, Paulson OB, Secher NH. Command-related distribution of regional cerebral blood flow during attempted handgrip. J Appl Physiol 1999;86(3):819-24.
Strauss GI, Høgh P, Møller K, Knudsen GM, Hansen BA, Larsen FS. Regional cerebral blood flow during mechanical hyperventilation in patients with fulminant hepatic failure. Hepatology 1999;30:1368-1373.
Videbæk C, Ott P, Paulson OB, Knudsen GM. Blood-brain barrier transport and protein binding of flumazenil and iomazenil in the rat: Implications for neuroreceptor studies. J Cereb Blood Flow Metab 1999;19:948-55.

Tekstbøger, andre oversigtsartikler og ledere
Knudsen GM, Hasselbalch SG, Paulson OB. Induction of carrier mediated transport across the human blood-brain barrier. In: Paulson OB, Knudsen GM, Moos T, eds. Brain Barrier Systems. Copenhagen: Munksgaard 1999:321-38.
Knudsen GM, Paulson OB. In: Lorenzen I, Bendixen G, Hansen NE, eds. Medicinsk Kompendium. Multiple Choice. Copenhagen: Nyt Nordisk Forlag 1999:164-73.
Paulson OB, Boysen G, Krarup C, Knudsen GM, Sørensen PS. Neurologi. I: Lorenzen I, Bendixen G, Hansen NE, eds. Medicinsk Kompendium, 15. udgave. København: Nyt Nordisk forlag Arnold Busck A/S 1999:2481-2677.
Paulson OB, Knudsen GM, Moos T, eds. Brain Barrier Systems. Alfred Benzon Symposium 45. Copenhagen: Munksgaard 1999:1-524.
Strandgaard S, Paulson OB. Hypertension and brain. In: Anand MP, Billimoria AR, eds. Hypertension - An international monograph 2000. New Delhi: IJCP Group of Publications, 1999:133-8.
Strandgaard S, Paulson OB. Management of hypertension with cerebrovascular disease. In: Anand MP, Billimoria AR, eds. Hypertension - An international monograph 2000. New Delhi: IJCP Group of Publications, 1999:233-6.
Sørensen PS, Paulson OB, Gjerris F. Nervesystemets sygdomme. 2. udgave. København: FADL, 1999.
 
 

1998

Disputatser og ph.d.-afhandlinger
Larsen FS. Cerebral circulation in liver failure. Cerebral circulation in liver failure: Ohm's law in force. Semin Liver Dis 1996;16:281-92. (Trykt i 1996 men forsvaret januar 1998).
Lassen U. Positron emission tomography (PET) of malignant tumors. Ph.d.-afhandling.
Mørch N.A multivariate approach to functional neuro modeling. Ph.d.-afhandling.

Originale publikationer i peer-reviewed journals
Hasselbalch SG, Madsen PL, Knudsen GM, Holm S, Paulson OB. Calculation of the FDG lumped constant by simultaneous measurements of global glucose and FDG metabolism in humans. J Cereb Blood Flow Metab 1998;18:154-60.
Jernigan T, Ostergaard AL, Law I, Svarer C, Gerlach C, Paulson OB. Brain activation during word identification and word recognition. Neuroimage 1998;8:93-105.
Lassen U, Andersen P, Daugaard G, Holm S, Jensen M, Svarer C, Poulsen HS, Paulson OB. Metabolic and hemodynamic evaluation of brain metastases from small cell lung cancer with positron emission tomography. Clin Cancer Res 1998;4:2591-7.
Law I, Svarer C, Rostrup E, Paulson OB. Parieto-occipital cortex activation during self-generated eye movements in the dark. Brain 1998;121:2189-2200.
Madsen PL, Linde R, Hasselbalch SG, Paulson OB, Lassen NA. Activation-induced resetting of cerebral oxygen and glucose uptake in the rat. J Cereb Blood Flow Metab 1998;18:742-8.
Strauss G, Hansen BA, Knudsen GM, Larsen FS. Hyperventilation restores cerebral blood flow autoregulation in patients with acute liver failure. J Hepatol 1998;28:199-203.
Vraamark T, Waldemar G, Paulson OB. Differential effects of migraine drugs on cerebral blood flow. Cephalalgia 1998;18:306-12.

Tekstbøger, andre oversigtsartikler og ledere
Ardekani BA, Strother SC, Anderson JR, Law I, Paulson OB, Kanno I, Rottenberg DA. On the detection of activation patterns using principal components analysis. In: Carson RE, Daube-Witherspoon ME, Herscovitch P, eds. Quantitative functional brain imaging with positron emission tomography. San Diego: Academic Press 1998:253-7.
Baron JC (chairman), Lenzi GL, Brücke T, Frackowiak R, Heiss WD, Pantano P, Paulson OB, Rossini PM, Schoenen J, Touboul PJ, Vion-Dury J, Von Kummer R. European Federation of Neurological Societies Task Force on Neuroimaging: Neuroimaging in European academic neurology: present status and future organization. Eur J Neurol 1998;5:5-15.
Knudsen GM, Paulson OB. Measurement of blood-brain barrier in humans using indicator diffusion. In: Pardridge WM, ed. Introduction to the blood-brain barrier. Methodology, biology and pathology. Cambridge: Cambridge University Press 1998:133-9.
Olsen KS. The influence of ketanserin on cerebral hemodynamics - with special reference to neuroanesthesia. Dan Med Bull 1998;45:76-88.
Paulson OB. Hjernens blodforsyning. Ugeskr Læger 1998:11:1612-13.
 
 

1997

Disputatser og  ph.d.-afhandlinger
Blinkenberg M. Ph.d.-afhandling. Regional cerebral metabolism in patients with multiple sclerosis.
Law I. Ph.d.-afhandling. Saccadic eye movements. A functional brain mapping approach.
Olsen KS. Disputats. The influence of ketanserin on cerebral hemodynamics - with special reference to neuroanesthesia. København: Lægeforeningens Forlag 1997.

Originale publikationer i peer-reviewed journals
Bay-Hansen J, Ravn T, Knudsen GM. Application of interhemispheric index for transcranial doppler sonography velocity measurements and evaluation of recording time. Stroke 1997;28:1009-14.
Bergström KA, Halldin C, Yu MX, Swahn C-G, Åkerman KK, Hiltunen J, Tiihonen J, Kuikka J, Lassen N, Videbæk C, Farde L. The metabolite pattern of [123I]epidepride in human plasma determined with a gradient HPLC method. J Label Comp Radiopharm 1997;40:151-3.
Law I, Svarer C, Holm S, Paulson OB. The activation pattern i n normal humans during suppression, imagination and performance of saccadic eye movements. Acta Physiol Scand 1997;161:419-34.
Mørch N, Hansen LK, Strother SC, Svarer C, Rottenberg DA, Lautrup B, Savoy R, Paulson OB. Nonlinear versus linear models in functional neuroimaging: Learning curves and generalization crossover. In: Duncan J, Gindi G, eds. Information Processing in Medical Imaging. Berlin Heidelberg: Springer Verlag.  Lecture notes in computer science 1997;1230:259-70.
Vraamark T, Waldemar G, Edvinsson L, Paulson OB. Differential effects of increasing doses of alfa-trinositol on cerebral blood flow autoregulation. Pharmacol & Toxicol 1997;80:38-43.

Tekstbøger, andre oversigtsartikler og ledere
Lassen NA, Paulson OB. Indomethacin nedsætter hjernegennemblødningen og det intrakranielle tryk. Ugeskr Læger 1997;159:4249.
Paulson OB, Hasselbalch SG. Blood-brain barrier transport of glucose: adaptation to changes in blood glucose levels. Nutr Metab Cardiovasc Dis 1997;7:217-24.
Paulson OB, Lassen NA. SPECT og PET i neurobiologien. Nord Med 1997;112:356-60.
Paulson OB, Lassen NA. SPECT og PET i neurobiologien. Ugeskr Læger 1997;159/16:2351-5.
Strandgaard S, Paulson OB. The cerebral circulation in hypertension. In: Zanchetti A, Mancia G, eds. Pathophysiology of hypertension. Amsterdam: Elsevier Science 1997;17:265-94.
Waldemar G, Høgh P, Paulson OB. Functional brain imaging with SPECT in the diagnosis of Alzheimer’s disease. Intern Psychoger 1997/Suppl 1;9:223-7.
 
 

1996

Disputatser
Waldemar G. Functional brain imaging with SPECT in normal aging and dementia. Methodological, pathophysiological, and diagnostic aspects. Cerebrovasc Brain Metab Rev 1995;7:89-130 (antaget og forsvaret i 1996).

Originale publikationer i peer-reviewed journals
Andersen AR, Hansen BR, Høgenhaven H, Herning M, Paulson O, Dam M. Interictal SPECT of rCBF is of clinical utility in the preoperative evaluation of patients with partial epilepsy. Epilepsy Res 1996;25:41-50.
Blinkenberg M, Bonde C, Holm S, Svarer C, Andersen J, Paulson OB, Law I. Rate dependence of regional cerebral activation during performance of a repetitive motor task: a PET study. J Cereb Blood Flow Metab 1996;16:794-803.
Blinkenberg M, Rune K, Jønsson A, Holm S, Jensen CV, Paulson OB, Sørensen PS. Cerebral metabolism in a case of multiple sclerosis with acute mental disorder. Acta Neurologica Scandinavica 1996;94:310-3.
Boller F, Duyckaerts C, Paulson OB, Vorstrup S, Soelberg Sørensen P. Prion related diseases and Creutzfeldt-Jakob disease (subacute spongiform encephalopathy). Eur J Neurol 1996;3:485-6.
EU concerted action on functional imaging: Poline J-B, Vandenberghe R, Holmes AP, Friston KJ, Frackowiak RSJ et al. Reproducibility of PET activation studies: Lessons from a multi-center European experiment. Neuroimage 1996;4:34-54.
Hasselbalch SG, Madsen PL, Hageman LP, Olsen KS, Justesen N, Holm S, Paulson OB. Changes in cerebral blood flow and carbohydrate metabolism during acute hyperketonemia. Am J Physiol 1996;270 (Endocrinol Metab 33):E746-51.
Hasselbalch SG, Knudsen GM, Holm S, Hageman LP, Capaldo B, Paulson OB. Transport of d-glucose and 2-fluorodeoxyglucose across the blood-brain barrier in humans. J Cereb Blood Flow Metabol 1996;16:659-66.
Hasselbalch S, Knudsen GM, Toft PB, Høgh P, Tedeschi E, Holm S, Videbæk C, Henriksen O, Lou HC, Paulson OB. Cerebral glucose metabolism is decreased in white matter changes in patients with phenylketonuria. Pediatr Res 1996;40:21-4.
Larsen FS, Hansen BA, Ejlersen E, Secher NH, Clemmesen JO, Tygstrup N, Knudsen GM. Cerebral blood flow, oxygen metabolism and transcranial Doppler sonography during high-volume plasmapheresis in fulminant hepatic failure. Eur J Gastroenterol Hepatol 1996;8:261-65.
Larsen FS, Hansen BA, Pott F, Ejlersen E, Secher NH, Paulson OB, Knudsen GM. Dissociated cerebral vasoparalysis in acute liver failure. J Hepatol 1996;25:145-151.

Tekstbøger, andre oversigtsartikler og ledere
Gjerris F, Paulson OB. Centralnervesystemets kirurgiske sygdomme. I: Hald T, Stadil F, eds. Kirurgisk Kompendium. 2. udgave. København: Nyt Nordisk Forlag Arnold Busck 1996:355-402.
Gjerris F, Paulson OB. Degenerative osteoartrotiske sygdomme i columna, diskusprolaps og kirurgiske sygdomme i det perifere nervesystem. I: Hald T, Stadil F, eds. Kirurgisk Kompendium, 2. udgave. København: Nyt Nordisk Forlag Arnold Busck 1996:433-59.
Knudsen GM, Paulson OB. Neurologiske og neuromuskulære sygdomme. I: Lorenzen I, Bendixen G, Hansen NE, eds. Medicinsk Kompendiums Lommebog. København: Nyt Nordisk Forlag Arnold Busck A/S, 1996:415-52.
Paulson OB. De neurologiske artikler. I: Holm-Nielsen N, ed. Klinisk Ordbog. København: Munksgaard 1996.
Paulson OB. Billeddiagnostik af hjernens funktion. Lundbeckfonden "Årsberetning 1995" 1996:18-19.
Paulson OB, Gjerris F, Sørensen PS, Juhler M. Klinisk neurologi og neurokirurgi. 2. udg. København: FADL, 1996.
Strandgaard S, Paulson OB. Antihypertensive drugs and cerebral circulation. Eur J Clin Invest 1996;26-625-30.
Vorstrup S, Paulson OB. Prionsygdomme. Ugeskr Læger 1996;158:4061.
Vorstrup S, Haase J, Waldemar G, Andersen A, Schmidt J, Paulson OB. EC-IC bypass in patients with chronic hemodynamic insufficiency. Acta Neurol Scand 1996/Suppl 166:79-81. Kongresmeddelelser
European concerted action on functional imaging, Cologne, Copenhagen, Düsseldorf, Essen, Groeningen Leuven, Liege, London, Lyon, Milan, Orsay, Stockholm (Rapporteur: J-B. Poline). Analyzing a European PET activation study. Lessons from a multi-center experiment. In: Myers R, Cunningham V, Bailey D, Jones T, eds. Quantification of brain function using PET. London: Academic Press 1996:372-7.
Holm S, Law I, Paulson OB. 3D PET activation studies with an H215O bolus injection. In: Myers R, Cunningham V, Bailey D, Jones T, eds. Quantification of brain function using PET. San Diego: Academic Press, 1996:93-7.
Larsen J, Hansen LK, Svarer C, Ohlsson M. Design and regularization of neural networks: The optimal use of a validation set. In: Usui S et al., eds. Neural networks for signal processing VI. Piscataway, NJ: IEEE, 1996:62-71.
Rostrup E, Law I, Blinkenberg M, Larsson HBW, Born P, Paulson OB. A combined PET and MRI study of human CBF in hypercapnia. Proceedings of the International Society for Magnetic Resonance in Medicine. Fourth International Meeting and Exhibition 1996, S1762.
Svarer C, Law I, Holm S, Mørch N, Hasselbalch S, Hansen LK, Paulson OB. An artificial neural network approach to estimation of the regional glucose metabolism using PET. In: Myers R, Cunningham V, Bailey D, Jones T, eds. Quantification of brain function using PET. San Diego: Academic Press, 1996:271-6.