Visiting Scientists and Associated Researchers


Sebastian Holst
Post Doc, Engineer
Dept. Neurology and Neurobiology Research Unit,
Copenhagen University Hospital, Rigshospitalet,
Building 6931,
Blegdamsvej 9, DK-2100 Copenhagen, Denmark

Curriculum vitae

Scientific interests:

Sleep research, pharmacogenetics and neuroscience.


2017 - Post Doc at the Neurobiology Research Unit
2013 - 2016 Post Doc at the Institute of Pharmacology and Toxicology, University of Zurich
2010 - 2013 PhD in Integrative Molecular Medicine and sleep research at the Institute of Pharmacology and Toxicology, University of Zurich
2010 ESRS Marie Curie program, Training in Sleep Research and Sleep Medicine


2016  Best abstract, Gordon-Kenan Research Seminar, Sleep Regulation & Function, Galveston, Texas, USA
2015  Bobérly-Hess Fellowship, the Swiss Society for Sleep Research, Sleep Medicine and Chronobiology
2014  Best presentation award, Spring Meeting of the Swiss Society of Pharmacology and Toxicology


  • Urry E, Jetter A, Holst SC, Berger W, Spinas, GA, Langhans W, Landolt H-P. A case-control field study on the relationships among type 2 diabetes, sleepiness and habitual caffeine intake. Journal of Psychopharmacology. 2016; 0269881116668595.
  • Landolt H-P, Holst SC. Ionic control of sleep and wakefulness. Science. 2016;352(6285):517-518.
  • Holst SC, Valomon A, Landolt H-P. Sleep Pharmacogenetics: Personalized Sleep-Wake Therapy. Annual review of pharmacology and toxicology. 2016;56:577-603.
  • Holst SC, Landolt H-P. Sleep homeostasis, metabolism, and adenosine. Current Sleep Medicine Reports. 2015;1(1):27-37.
  • Landolt H-P, Sousek A, Holst SC. Effects of acute and chronic sleep deprivation, ESRS. European Sleep Medicine Textbook, ESRS. 2014.
  • Valomon A, Holst SC, Bachmann V, Viola AU, Schmidt C, Zürcher J, Landolt H-P. Genetic polymorphisms of DAT1 and COMT differentially associate with actigraphy-derived sleep-wake cycles in young adults. Chronobiology international. 2014;31(5):705-714.
  • Holst SC, Bersagliere A, Bachmann V, Berger W, Achermann P, Landolt H-P. Dopaminergic role in regulating neurophysiological markers of sleep homeostasis in humans. The Journal of Neuroscience. 2014;34(2):566-573.
  • Hefti K, Holst SC, Sovago J, Bachmann V, Buck A, Ametamey SM, Landolt H-P. Increased metabotropic glutamate receptor subtype 5 availability in human brain after one night without sleep. Biological psychiatry. 2013;73(2):161-168.