Brain disorders diagnosed with 7 Tesla MR (7 Tesla)

The 7 Tesla (7T) MRI projects are focused on the benefit of 7T MRI in the clinic. Among other promising contributions when compared to conventional clinical MRI (1.5 or 3T), structural images from 7T MRI have the benefit of increased spatial resolution and contrast, which may help radiologists detect and delineate smaller and more precise details.

7T Epilepsy: We have scanned 62 patients with epilepsy in the national 7T MR scanner at Hvidovre Hospital as part of their presurgical evaluation, to assess the contribution of 7T MR compared to regular 3T MR in the clinic. Patient enrollment has stopped, and data (both structural and functional MRI) is currently being analysed. We also scanned 61 healthy participants.

7T Tumor: We are currently scanning patients with low-grade gliomas to retrospectively evaluate the influence of the sub-millimeter scans with increased signal to noise ratio (SNR) from 7T MR on tumor border delineation. In the tumor study, we are collecting H-MRS, functional MRI and DTI data from both patients and healthy participants as well.

7T MoCo: In parallel to these clinical studies, we will evaluate the effects of using motion correction as part of 7T MR protocol specific to epilepsy. This study is ongoing, and when all data (15 healthy subjects) has been acquired, the images will be rated by several independent neuroradiologists, to assess differences in quality between scans with and without motion and correction. With this method development focus, we can highlight the yield of implementing robust and cost-free motion correction techniques at 7T MRI, which holds relevance to patient groups with any brain disorder with structural brain changes.

The enrollment status in the three subprojects is displayed below: