Annual Reports:

• Marner L. Communication among neurons. Quantitative measures in aging and disease. Defended Sep 16, 2011.
• Pinborg LH. Molecular imaging of receptors and transporters in humans using PET and SPECT: from models to methods and potentials to pitfalls. Defended Jun 4, 2009.
• Gerlach C. Disputats: Visual object recognition and category-specificity. Defended Nov 7, 2008.
• Law I. Human brain mapping under increasing cognitive complexity using regional cerebral blood flow measurements and positron emission tomography. Defended Aug 31, 2007.
• Møller K. Cerebral blood flow and metabolism in adults with acute bacterial meningitis. Defended Aug 24, 2007.
• Strauss GI. The effect of hyperventilation upon cerebral blood flow and metabolism in patients with fulminant hepatic failure. Defended Mar 30, 2007.
• Hasselbalch SG. Quantitation of brain metabolism in humans using PET-FDG: levels and limitations. Defended Apr 25, 2003.
• Videbæk C. Single photon emission tomography for neuroreceptor studies: Methodological considerations. Defended in 2002.
• Larsen FS. Cerebral circulation in liver failure: Ohm's law in force. Semin Liver Dis 1996;16:281-92. Defended in 1998.
• Olsen KS. The influence of ketanserin on cerebral hemodynamics - with special reference to neuroanesthesia. Defended in 1997.
• Waldemar G. Functional brain imaging with SPECT in normal aging and dementia. Methodological, pathophysiological, and diagnostic aspects. Cerebrovasc Brain Metab Rev 1995;7:89-130. Defended in 1996.
• Knudsen GM. Application of the double-indicator technique for measurement of blood-brain barrier permeability in humans.Cerebrovasc Brain Metab Rev. 1994 Spring;6(1):1-30. Defended in 1994.
  
  

• Paulson OB, Gjerris F, Sørensen PS, Waldemarn G, Sørensen JH, Sellebjerg F (eds). Klinisk neurologi og neurokirurgi. 7. udg. København: FADL’s forlag. 2020:1-773.

2019

• Agren T, Millroth P, Andersson P, Ridzén M, Björkstrand J. Detailed analysis of skin conductance responses during a gambling task: Decision, anticipation, and outcomes. Psychophysiology. 2019 Jun;56(6):e13338
• Bach Justesen A, Foged MT, Fabricius M, Skaarup C, Hamrouni N, Martens T, Paulson OB, Pinborg LH, Beniczky S. Diagnostic yield of high-density versus low-density EEG: The effect of spatial sampling, timing and duration of recording. Clin Neurophysiol. 2019 Nov;130(11):2060-206
• Bærentzen S, Casado-Sainz A, Lange D, Shalgunov V, Tejada IM, Xiong M, L'Estrade ET, Edgar FG, Lee H, Herth MM, Palner M. The Chemogenetic Receptor Ligand Clozapine N-Oxide Induces in vivo Neuroreceptor Occupancy and Reduces Striatal Glutamate Levels. Front Neurosci. 2019 Apr 3;13:187
• Christensen CE, Amin FM, Younis S, Lindberg U, de Koning P, Petersen ET, Paulson OB, Larsson HBW, Ashina M. Sildenafil and calcitonin gene-related peptide dilate intradural arteries: A 3T MR angiography study in healthy volunteers. Cephalalgia. 2019 Feb;39(2):264-273
• Christensen CE, Younis S, Lindberg U, Boer VO, de Koning P, Petersen ET, Paulson OB, Larsson HBW, Amin FM, Ashina M. Ultra-high field MR angiography in human migraine models: a 3.0 T/7.0 T comparison study. J Headache Pain. 2019 May 6;20(1):48
• da Cunha-Bang S, Fisher PM, Hjordt LV, Holst K, Knudsen GM. Amygdala reactivity to fearful faces correlates positively with impulsive aggression. Soc Neurosci. 2019 Apr;14(2):162-172
• da Cunha-Bang S, Ettrup A, Mc Mahon B, Skibsted AP, Schain M, Lehel S, Dyssegaard A, Jørgensen LM, Møller K, Gillings N, Svarer C, Knudsen GM. Measuring endogenous changes in serotonergic neurotransmission with [11C]Cimbi-36 positron emission tomography in humans. Transl Psychiatry. 2019 Apr 11;9(1):134
• Dam VH, Thystrup CK, Jensen PS, Bland AR, Mortensen EL, Elliott R, Sahakian BJ, Knudsen GM, Frokjaer VG, Stenbæk DS. Psychometric Properties and Validation of the EMOTICOM Test Battery in a Healthy Danish Population. Front Psychol. 2019 Dec 3;10:2660
• Deen M, Hougaard A, Hansen HD, Svarer C, Eiberg H, Lehel S, Knudsen GM, Ashina M. Migraine is associated with high brain 5-HT levels as indexed by 5-HT4 receptor binding. Cephalalgia. 2019 Apr;39(4):526-532
• Deen M, Hougaard A, Hansen HD, Schain M, Dyssegaard A, Knudsen GM, Ashina M. Association Between Sumatriptan Treatment During a Migraine Attack and Central 5-HT1B Receptor Binding. JAMA Neurol. 2019 Jul 1;76(7):834-840
• Duez L, Tankisi H, Hansen PO, Sidenius P, Sabers A, Pinborg LH, Fabricius M, Rásonyi G, Rubboli G, Pedersen B, Leffers AM, Uldall P, Jespersen B, Brennum J, Henriksen OM, Fuglsang-Frederiksen A, Beniczky S. Electromagnetic source imaging in presurgical workup of patients with epilepsy: A prospective study. Neurology. 2019 Feb 5;92(6):e576-e586
• Dyrvig M, Mikkelsen JD, Lichota J. DNA methylation regulates CHRNA7 transcription and can be modulated by valproate. Neurosci Lett. 2019 Jun 21;704:145-152
• Ebert SE, Jensen P, Ozenne B, Armand S, Svarer C, Stenbaek DS, Moeller K, Dyssegaard A, Thomsen G, Steinmetz J, Forchhammer BH, Knudsen GM, Pinborg LH. Molecular imaging of neuroinflammation in patients after mild traumatic brain injury: a longitudinal 123 I-CLINDE SPECT study. Eur J Neurol. 2019 Dec;26(12):1426-1432
• Erritzoe D, Smith J, Fisher PM, Carhart-Harris R, Frokjaer VG, Knudsen GM. Recreational use of psychedelics is associated with elevated personality trait openness: Exploration of associations with brain serotonin markers. J Psychopharmacol. 2019 Sep;33(9):1068-1075
• Foged MT, Stefánsdóttir A, Brændgaard M, Holm E, Pinborg LH, Sabers A. Why are antiepileptic drugs continued after successful epilepsy surgery in adults? Epilepsy Behav. 2019 Nov;100(Pt A):106452
• Frederiksen KS, Madsen K, Andersen BB, Beyer N, Garde E, Høgh P, Waldemar G, Hasselbalch SG, Law I. Moderate- to high-intensity exercise does not modify cortical β-amyloid in Alzheimer's disease. Alzheimers Dement (N Y). 2019 Jun 7;5:208-215
• Galea LAM, Frokjaer VG. Perinatal Depression: Embracing Variability toward Better Treatment and Outcomes. Neuron. 2019 Apr 3;102(1):13-16
• Griem-Krey N, Klein AB, Herth M, Wellendorph P. Autoradiography as a Simple and Powerful Method for Visualization and Characterization of Pharmacological Targets. J Vis Exp. 2019 Mar 12;(145)
• Hansen HD, Constantinescu CC, Barret O, Herth MM, Magnussen JH, Lehel S, Dyssegaard A, Colomb J, Billard T, Zimmer L, Tamagnan G, Knudsen GM. Evaluation of [18 F]2FP3 in pigs and non-human primates. J Labelled Comp Radiopharm. 2019 Jan;62(1):34-42
• Heurling K, Smith R, Strandberg OT, Schain M, Ohlsson T, Hansson O, Schöll M. Regional times to equilibria and their impact on semi-quantification of [18F]AV-1451 uptake. J Cereb Blood Flow Metab. 2019 Nov;39(11):2223-2232
• Hjordt LV, Stenbæk DS. Sensory processing sensitivity and its association with seasonal affective disorder. Psychiatry Research. 2019 Feb;272:359-364
• Holm SK, Madsen KS, Vestergaard M, Born AP, Paulson OB, Siebner HR, Uldall P, Baaré WFC. Previous glucocorticoid treatment in childhood and adolescence is associated with long-term differences in subcortical grey matter volume and microstructure. Neuroimage Clin. Neuroimage Clin. 2019;23:101825
• Holmgaard F, Vedel AG, Rasmussen LS, Paulson OB, Nilsson JC, Ravn HB. The association between postoperative cognitive dysfunction and cerebral oximetry during cardiac surgery: a secondary analysis of a randomised trial. Br J Anaesth. 2019 Aug;123(2):196-205
• Jensen CG, Krogh SC, Westphael G, Hjordt LV. Mindfulness is positively related to socioeconomic job status and income and independently predicts mental distress in a long-term perspective: Danish validation studies of the Five-Factor Mindfulness Questionnaire. Psychol Assess. 2019 Jan;31(1):e1-e20
• Johansen A, Holm S, Dall B, Keller S, Kristensen JL, Knudsen GM, Hansen HD. Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions. EJNMMI Res. 2019 Jul 31;9(1):71
• Kjær C, Barzaghi G, Bak LK, Goetze JP, Yde CW, Woldbye D, Pinborg LH, Jensen LJ. Transcriptome analysis in patients with temporal lobe epilepsy. Brain. 2019 Oct 1;142(10):e55
• Kuypers KP, Ng L, Erritzoe D, Knudsen GM, Nichols CD, Nichols DE, Pani L, Soula A, Nutt D. Microdosing psychedelics: More questions than answers? An overview and suggestions for future research. J Psychopharmacol. 2019 Sep;33(9):1039-1057
• Lansner J, Jensen CG, Petersen A, Fisher PM, Frokjaer VG, Vangkilde S, Knudsen GM. Three weeks of SSRI administration enhances the visual perceptual threshold - a randomized placebo-controlled study. Psychopharmacology (Berl). 2019 Jun;236(6):1759-1769
• Larsen LK, Frøkjaer VG, Nielsen JS, Skrobik Y, Winkler Y, Møller K, Petersen M, Egerod I. Delirium assessment in neuro-critically ill patients: A validation study. Acta Anaesthesiol Scand. 2019 Mar;63(3):352-359
• Larsen HM, Hansen SK, Mikkelsen JD, Hyttel P, Stummann TC. Alpha7 nicotinic acetylcholine receptors and neural network synaptic transmission in human induced pluripotent stem cell-derived neurons. Stem Cell Res. 2019 Dec;41:101642
• López-Picón FR, Kirjavainen AK, Forsback S, Takkinen JS, Peters D, Haaparanta-Solin M, Solin O. In vivo characterization of a novel norepinephrine transporter PET tracer [18F]NS12137 in adult and immature Sprague-Dawley rats. Theranostics. 2019 Jan 1;9(1):11-19
• L'Estrade ET, Hansen HD, Falk-Petersen C, Haugaard A, Griem-Krey N, Jung S, Lüddens H, Schirmeister T, Erlandsson M, Ohlsson T, Knudsen GM, Herth MM, Wellendorph P, Frølund B. Synthesis and Pharmacological Evaluation of [11C]4-Methoxy-N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the δ-Subunit-Containing γ-Aminobutyric Acid Type A Receptors. ACS Omega. 2019 May 22;4(5):8846-8851
• Madsen MK, Fisher PM, Burmester D, Dyssegaard A, Stenbæk DS, Kristiansen S, Johansen SS, Lehel S, Linnet K, Svarer C, Erritzoe D, Ozenne B, Knudsen GM. Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels. Neuropsychopharmacology. 2019 Jun;44(7):1328-1334
• Magnusson PO, Boer VO, Marsman A, Paulson OB, Hanson LG, Petersen ET. Gamma-aminobutyric acid edited echo-planar spectroscopic imaging (EPSI) with MEGA-sLASER at 7T. Magn Reson Med. 2019 Feb;81(2):773-780
• Mehta D, Rex-Haffner M, Søndergaard HB, Pinborg A, Binder EB, Frokjaer VG. Genome-wide gene expression in a pharmacological hormonal transition model and its relation to depressive symptoms. Acta Psychiatr Scand. 2019 Jul;140(1):77-84
• Mehta D, Rex-Haffner M, Søndergaard HB, Pinborg A, Binder EB, Frokjaer VG. Evidence for oestrogen sensitivity in perinatal depression: pharmacological sex hormone manipulation study. Br J Psychiatry. 2019 Sep;215(3):519-527
• Nørgaard M, Ganz M, Svarer C, Feng L, Ichise M, Lanzenberger R, Lubberink M, Parsey RV, Politis M, Rabiner EA, Slifstein M, Sossi V, Suhara T, Talbot PS, Turkheimer F, Strother SC, Knudsen GM. Cerebral serotonin transporter measurements with [11C]DASB: A review on acquisition and preprocessing across 21 PET centres. J Cereb Blood Flow Metab. 2019 Feb;39(2):210-222
• Nørgaard M, Ganz M, Svarer C, Frokjaer VG, Greve DN, Strother SC, Knudsen GM. Optimization of preprocessing strategies in Positron Emission Tomography (PET) neuroimaging: A [11C]DASB PET study. NeuroImage. 2019 Jun 1;199:466-479
• Ozenne B, Tae-Hee C, Mikkelsen IK, Hermier M, Thomalla G, Pedraza S, Roy P, Berthezène Y, Nighoghossian N, Østergaard L, Baron JC, Maucort-Boulch D. Individualized Quantification of the Benefit from Reperfusion Therapy using Stroke Predictive Models. Eur J Neurosci. 2019 Oct;50(8):3251-3260
• Peinkhofer C#, Knudsen GM, Moretti R, Kondziella D#. Cortical modulation of pupillary function: systematic review. PeerJ. 2019 May 7;7:e6882.
• Prabhakaran J, DeLorenzo C, Zanderigo F, Knudsen GM, Gilling N, Pratap M, Jorgensen MJ, Daunais J, Kaplan JR, Parsey RV, Mann JJ, Kumar D. In vivo PET Imaging of [11C]CIMBI-5, a 5-HT2AR Agonist Radiotracer in Nonhuman Primates. J Pharm Pharm Sci. 2019;22(1):352-364
• Sigurdsson ST, Bie P, Nielsen AH, Strandgaard S, Paulson OB. No effect of the angiotensin receptor blocker candesartan on cerebrovascular autoregulation in rats during very high and low sodium intake. J Renin Angiotensin Aldosterone Syst. 2019 Jul-Sep; 20(3): 1470320319874615
• Stéen EJL, Jørgensen JT, Petersen IN, Nørregaard K, Lehel S, Shalgunov V, Birke A, Edem PE, L'Estrade ET, Hansen HD, Villadsen J, Erlandsson M, Ohlsson T, Yazdani A, Valliant JF, Kristensen JL, Barz M, Knudsen GM, Kjær A, Herth MM. Improved radiosynthesis and preliminary in vivo evaluation of the 11C-labeled tetrazine [11C]AE-1 for pretargeted PET imaging. Bioorg Med Chem Lett. 2019 Apr 15;29(8):986-990
• Stenbæk DS, Budtz-Jørgensen E, Pinborg A, Jensen PS, Frokjaer VG. Neuroticism modulates mood responses to pharmacological sex hormone manipulation in healthy women. Psychoneuroendocrinology. 2019 Jan;99:251-256
• Stenbaek DS, Kristiansen S, Burmester D, Madsen MK, Frokjaer VG, Knudsen GM, Fisher PM. Trait Openness and serotonin 2A receptors in healthy volunteers: A positron emission tomography study. Hum Brain Mapp. 2019 May;40(7):2117-2124
• Sundström Poromaa I, Comasco E, Bäckström T, Bixo M, Jensen P, Frokjaer VG. Negative Association Between Allopregnanolone and Cerebral Serotonin Transporter Binding in Healthy Women of Fertile Age. Front Psychol. 2019 Jan 11;9:2767
• Svensson JE, Schain M, Plavén-Sigray P, Cervenka S, Tiger M, Nord M, Halldin C, Farde L, Lundberg J. Validity and reliability of extrastriatal [11C]raclopride binding quantification in the living human brain. Neuroimage. 2019 Aug 29;202:116143
• Tampio L'Estrade E, Xiong M, Shalgunov V, Edgar FG, Volk B, Baerentzen SL, Palner M, Erlandsson M, Ohlsson T, Knudsen GM, Herth MM. Development and Evaluation of Two Potential 5-HT7 Receptor PET Tracers: [18F]ENL09 and [18F]ENL10. ACS Chem Neurosci. 2019 Sep 18;10(9):3961-3968
• Tozlu C, Ozenne B, Tae-Hee C, Nighoghossian N, Mikkelsen IK, Derex L, Hermier M, Pedraza S, Fiehler J, Østergaard L, Berthezène Y, Baron JC, Maucort-Boulch D. Comparison of classification methods for tissue outcome after ischaemic stroke. Eur J Neurosci. 2019 Nov;50(10):3590-3598
• Vassilieva A, Olsen MH, Peinkhofer C, Knudsen GM, Kondziella D. Automated pupillometry to detect command following in neurological patients: a proof-of-concept study. PeerJ. 2019 May 13;7:e6929
• Vedel AG, Holmgaard F, Siersma V, Langkilde A, Paulson OB, Ravn HB, Nilsson JC, Rasmussen LS. Domain-specific cognitive dysfunction after cardiac surgery. A secondary analysis of a randomized trial. Acta Anaesthesiol Scand. 2019 Jul;63(6):730-738
• Veronese M, Moro L, Arcolin M, Dipasquale O, Rizzo G, Expert P, Khan W, Fisher PM, Svarer C, Bertoldo A, Howes O, Turkheimer FE. Covariance statistics and network analysis of brain PET imaging studies. Sci Rep. 2019 Feb 21;9(1):2496
• Wickham J, Ledri M, Bengzon J, Jespersen B, Pinborg LH, Englund E, Woldbye DPD, Andersson M, Kokaia M. Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients. Sci Rep. 2019 Dec 18;9(1):19393.

• Holst SC, Werth E, Landolt HP. Pharmacotherapy of Sleep-Wake Disorders. Praxis (Bern 1994). 2019 Jan;108(2):131-138. https://doi.org/10.1024/1661-8157/a003189.
• Landolt HP, Holst SC, Valomon A. Clinical and Experimental Human Sleep-Wake Pharmacogenetics. Handb Exp Pharmacol. 2019;253:207-241. https://doi.org/10.1007/164_2018_175.
• Nørgaard M, Ozenne B, Svarer C, Frokjaer VG, Schain M, Strother SC, Ganz M. Preprocessing, Prediction, and Significance: Framework and Application to Brain Imaging. Springer Nature Switzerland AG 2019 D. Shen et al. (Eds.): MICCAI 2019, Lecture Notes in Computer Science 11767, pp. 196-204, 2019.

• Perani D, Iaccarino L, Jacobs AH; IMBI Brain Imaging Working Group. Application of advanced brain positron emission tomography-based molecular imaging for a biological framework in neurodegenerative proteinopathies. Alzheimers Dement (Amst). 2019 Apr 16;11:327-332
• Perani D, Iaccarino L, Lammertsma AA, Windhorst AD, Edison P, Boellaard R, Hansson O, Nordberg A, Jacobs AH; IMBI Project. A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies. Alzheimers Dement. 2019 Aug;15(8):1081-1103

2018

• Antonsen KK#, Klausen MK#, Brunchmann AS, le Dous N, Jensen ME, Miskowiak KW, Fisher PM, Thomsen GK, Rindom H, Fahmy TP, Vollstaedt-Klein S, Benveniste H, Volkow ND, Becker U, Ekstrøm C, Knudsen GM, Vilsbøll T, Fink-Jensen A. Does glucagon-like peptide-1 (GLP-1) receptor agonist stimulation reduce alcohol intake in patients with alcohol dependence: study protocol of a randomised, double-blinded, placebo-controlled clinical trial. BMJ Open. 2018 Jul 16;8(7):e019562
• Bailey DL, Pichler BJ, Gückel B, Antoch G, Barthel H, Bhujwalla ZM, Biskup S, Biswal S, Bitzer M, Boellaard R, Braren RF, Brendle C, Brindle K, Chiti A, la Fougère C, Gillies R, Goh V, Goyen M, Hacker M, Heukamp L, Knudsen GM, Krackhardt AM, Law I, Morris JC, Nikolaou K, Nuyts J, Ordonez AA, Pantel K, Quick HH, Riklund K, Sabri O, Sattler B, Troost EGC, Zaiss M, Zender L, Beyer T. Combined PET/MRI: Global Warming-Summary Report of the 6th International Workshop on PET/MRI, March 27-29, 2017, Tübingen, Germany. Mol Imaging Biol. 2018 Feb;20(1):4-20
• Baroumand AG, van Mierlo P, Strobbe G, Pinborg LH, Fabricius M, Rubboli G, Leffers AM, Uldall P, Jespersen B, Brennum J, Henriksen OM, Beniczky S. Automated EEG source imaging: A retrospective, blinded clinical validation study. Clin Neurophysiol. 2018 Sep 24;129(11):2403-2410
• Borgsted C, Ozenne⁠ B, Mc Mahon B, Madsen KM, Hjordt⁠ LV, Hageman⁠ I, Baaré⁠ WFC, Knudsen GM, Fisher PM. Amygdala response to emotional faces in seasonal affective disorder. J Affect Disord. 2018 Mar 15;229:288-295
• Carass A, Cuzzocreo JL, Han S, Hernandez-Castillo CR, Rasser PE, Ganz M, Beliveau V, Dolz J, Ben Ayed I, Desrosiers C, Thyreau B, Romero JE, Coupé P, Manjón JV, Fonov VS, Collins DL, Ying SH, Onyike CU, Crocetti D, Landman BA, Mostofsky SH, Thompson PM, Prince JL. Comparing fully automated state-of-the-art cerebellum parcellation from magnetic resonance images. Neuroimage. 2018 Aug 9;183:150-172
• da Cunha-Bang S, Fisher PM, Hjordt LV, Perfalk E, Beliveau V, Holst K, Knudsen GM. Men with high serotonin 1B receptor binding respond to provocations with heightened amygdala reactivity. Neuroimage. 2018 Feb 1;166:79-85
• Deco G, Cruzat J, Cabral J, Knudsen GM, Carhart-Harris RL, Whybrow PC, Logothetis NK, Kringelbach ML. Whole-Brain Multimodal Neuroimaging Model Using Serotonin Receptor Maps Explains Non-linear Functional Effects of LSD. Curr Biol. 2018 Oct 8;28(19):3065-3074
• Deen M, Hansen HD, Hougaard A, Nørgaard M, Eiberg H, Lehel S, Ashina M, Knudsen GM. High brain serotonin levels in migraine between attacks: A 5-HT4 receptor binding PET study. Neuroimage Clin. 2018 Jan 28;18:97-102
• Deen M, Hansen HD, Hougaard A, da Cunha-Bang S, Nørgaard M, Svarer C, Keller SH, Thomsen C, Ashina M, Knudsen GM. Low 5-HT1B receptor binding in the migraine brain: A PET study. Cephalalgia. 2018 Mar;38(3):519-527
• Foged MT, Vinter K, Stauning L, Kjær TW, Ozenne B, Beniczky S, Paulson OB, Madsen FF, Pinborg LH; Danish Epilepsy Surgery Group. Verbal learning and memory outcome in selective amygdalohippocampectomy versus temporal lobe resection in patients with hippocampal sclerosis. Epilepsy Behav. 2018 Feb;79:180-187.
• Hjordt LV, Dam VH, Ozenne B, Hageman I, Mc Mahon B, Mortensen EL, Knudsen GM, Stenbæk DS. Self-perceived personality characteristics in seasonal affective disorder and their implications for severity of depression. Psychiatry Res. 2018 Feb 6;262:108-114
• Holm E, Foged MT, Beniczky S, Jespersen B, Brennum J, Pinborg LH. Efficacy of the Danish Epilepsy Surgery Programme. Acta Neurol Scand. 2018 Feb;137(2):245-251
• Holm SK, Madsen KS, Vestergaard M, Paulson OB, Uldall P, Siebner HR, Born AP, Baaré WFC. Total brain, cortical and white matter volumes in children previously treated with glucocorticoids. Pediatr Res. 2018 Apr;83(4):804-812
• Holst SC, Landolt HP. Sleep-Wake Neurochemistry. Sleep Med Clin. 2018 Jun;13(2):137-146
• Hornboll B, Macoveanu J, Nejad A, Rowe J, Elliott R, Knudsen GM, Siebner HR, Paulson OB. Neuroticism predicts the impact of serotonin challenges on fear processing in subgenual anterior cingulate cortex. Sci Rep. 2018 Dec 17;8(1):17889
• Ip CT, Ganz M, Ozenne B, Sluth LB, Gram M, Viardot G, l'Hostis P, Danjou P, Knudsen GM, Christensen SR. Pre-intervention test-retest reliability of EEG and ERP over four recording intervals. Int J Psychophysiol. 2018 Sep 22;134:30-43
• Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O, Klunk WE, van der Flier WM, Villemagne VL, Frisoni GB, Fleisher AS, Lleó A, Mintun MA, Wallin A, Engelborghs S, Na DL, Chételat G, Molinuevo JL, Landau SM, Mattsson N, Kornhuber J, Sabri O, Rowe CC, Parnetti L, Popp J, Fladby T, Jagust WJ, Aalten P, Lee DY, Vandenberghe R, Resende de Oliveira C, Kapaki E, Froelich L, Ivanoiu A, Gabryelewicz T, Verbeek MM, Sanchez-Juan P, Hildebrandt H, Camus V, Zboch M, Brooks DJ, Drzezga A, Rinne JO, Newberg A, de Mendonça A, Sarazin M, Rabinovici GD, Madsen K, Kramberger MG, Nordberg A, Mok V, Mroczko B, Wolk DA, Meyer PT, Tsolaki M, Scheltens P, Verhey FRJ, Visser PJ; Amyloid Biomarker Study Group. Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia. JAMA Psychiatry. 2018 Jan 1;75(1):84-95
• Johansen A, Hansen HD, Svarer C, Lehel S, Leth-Petersen S, Kristensen JL, Gillings N, Knudsen GM. The importance of small polar radiometabolites in molecular neuroimaging: A PET study with [11C]Cimbi-36 labeled in two positions. J Cereb Blood Flow Metab. 2018 Apr;38(4):659-668
• Jørgensen LM, Weikop P, Svarer C, Feng L, Keller SH, Knudsen GM. Cerebral serotonin release correlates with [11C]AZ10419369 PET measures of 5-HT1B receptor binding in the pig brain. J Cereb Blood Flow Metab. 2018 Jul;38(7):1243-1252
• Kirjavainen AK, Forsback S, López-Picón FR, Marjamäki P, Takkinen J, Haaparanta-Solin M, Peters D, Solin O. 18F-labeled norepinephrine transporter tracer [18F]NS12137: radiosynthesis and preclinical evaluation. Nucl Med Biol. 2018 Jan;56:39-46
• Mc Mahon B, Nørgaard M, Svarer C, Andersen SB, Madsen MK, Baaré WFC, Madsen J, Frokjaer VG, Knudsen GM. Seasonality-resilient individuals downregulate their cerebral 5-HT transporter binding in winter - A longitudinal combined 11C-DASB and 11C-SB207145 PET study. Eur Neuropsychopharmacol. 2018 Oct;28(10):1151-1160
• Medger K, Bennett NC, Chimimba CT, Oosthuizen MK, Mikkelsen JD, Coen CW. Analysis of gonadotrophin-releasing hormone-1 and kisspeptin neuronal systems in the nonphotoregulated seasonally breeding eastern rock elephant-shrew (Elephantulus myurus). J Comp Neurol. 2018 Oct 15;526(15):2388-2405
• Miskowiak KW, Macoveanu J, Jørgensen MB, Støttrup MM, Ott CV, Jensen HM, Jørgensen A, Harmer J, Paulson OB, Kessing LV, Siebner HR. Neural response after a single ECT session during retrieval of emotional self-referent words in depression: a randomized, sham-controlled fMRI study. Int J Neuropsychopharmacol. 2018 Mar 1;21(3):226-235
• Miskowiak KW, Macoveanu J, Jørgensen MB, Ott CV, Støttrup MM, Jensen HM, Jørgensen A, Harmer CJ, Paulson OB, Siebner HR, Kessing LV. Effect of electroconvulsive therapy on neural response to affective pictures: A randomized, sham-controlled fMRI study. Eur Neuropsychopharmacol. 2018 Aug;28(8):915-924
• Mora S, Merchan A, Vilchez O, Aznar S, Klein AB, Ultved L, Campa L, Suñol C, Flores P, Moreno M. Reduced cortical serotonin 5-HT2A receptor binding and glutamate activity in high compulsive drinker rats. Neuropharmacology. 2018 Sep 7;143:10-19
• Oltedal L, Narr KL, Abbott C, Anand A, Argyelan M, Bartsch H, Dannlowski U, Dols A, van Eijndhoven P, Emsell L, Erchinger VJ, Espinoza R, Hahn T, Hanson LG, Hellemann G, Jorgensen MB, Kessler U, Oudega ML, Paulson OB, Redlich R, Sienaert P, Stek ML, Tendolkar I, Vandenbulcke M, Oedegaard KJ, Dale AM. Volume of the Human Hippocampus and Clinical Response Following Electroconvulsive Therapy. Biol Psychiatry. 2018 Oct 15;84(8):574-581
• Ott CV, Vinberg M, Bowie CR, Christensen EM, Knudsen GM, Kessing LV, Miskowiak KW. Effect of action-based cognitive remediation on cognition and neural activity in bipolar disorder: study protocol for a randomized controlled trial. Trials. 2018 Sep 12;19(1):487
• Overgaard A, Lieblich SE, Richardson R, Galea LAM, Frokjaer VG. Paroxetine blunts the corticosterone response to swim-induced stress and increases depressive-like behavior in a rat model of postpartum depression. Psychoneuroendocrinology. 2018 Mar;89:223-228
• Peinkhofer C, Martens P, Grand J, Truelsen T, Knudsen GM, Kjaergaard J, Kondziella D. Influence of Strategic Cortical Infarctions on Pupillary Function. Front Neurol. 2018 Oct 29;9:916
• Petersen JZ, Schmidt LS, Vinberg M, Jørgensen MB, Hageman I, Ehrenreich H, Knudsen GM, Kessing LV, Miskowiak KW. Effects of recombinant human erythropoietin on cognition and neural activity in remitted patients with mood disorders and first-degree relatives of patients with psychiatric disorders: a study protocol for a randomized controlled trial. Trials. 2018 Nov 6;19(1):611
• Pinborg L, Jespersen B, Beniczky S, Fabricius M, Rasonyi G, Uldall P, Tsiropoulos I, Leffers AM, Madsen C, Foged M, Ziebell M, Henriksen O, Jørgensen M, Vinter K, Stauning L, Broholm H, Brennum J, Sabers A, Rubboli G. [Epilepsy surgery]. Ugeskr Laeger. 2018 Mar 26;180(13)
• Runegaard AH, Sørensen AT, Fitzpatrick CM, Jørgensen SH, Petersen AV, Hansen NW, Weikop P, Andreasen JT, Mikkelsen JD, Perrier JF, Woldbye D, Rickhag M, Wortwein G, Gether U. Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons. eNeuro. 2018 Jun 18;5(3):1-28
• Sharma P, Scherg M, Pinborg LH, Fabricius M, Rubboli G, Pedersen B, Leffers AM, Uldall P, Jespersen B, Brennum J, Henriksen OM, Beniczky S. Ictal and interictal electric source imaging in pre-surgical evaluation: a prospective study. Eur J Neurol. 2018 Sep;25(9):1154-1160
• Skibsted AP, Amiri M, Fisher PM, Sidaros A, Hribljan MC, Larsen VA, Højgaard JLS, Nikolic M, Hauerberg J, Fabricius ME, Knudsen GM, Møller K, Kondziella D. Consciousness in Neurocritical Care Cohort Study Using fMRI and EEG (CONNECT-ME): Protocol for a Longitudinal Prospective Study and a Tertiary Clinical Care Service. Front Neurol. 2018 Nov 27;9:1012
• Steensberg AT, Olsen AS, Litman M, Jespersen B, Kolko M, Pinborg LH. Visual field defects after temporal lobe resection for epilepsy. Seizure. 2018 Jan;54:1-6
• T L'Estrade E, Hansen HD, Erlandsson M, Ohlsson TG, Knudsen GM, Herth MM. Classics in Neuroimaging: The Serotonergic 2A Receptor System-from Discovery to Modern Molecular Imaging. ACS Chem Neurosci. 2018 Jun 20;9(6):1226-1229
• Vedel AG, Holmgaard F, Rasmussen LS, Langkilde A, Paulson OB, Lange T, Thomsen C, Olsen PS, Ravn HB, Nilsson JC. High-target versus low-target blood pressure management during cardiopulmonary bypass to prevent cerebral injury in cardiac surgery patients: A randomized controlled trial. Circulation. 2018 Apr 24;137(17):1770-1780
• Villadsen J, Hansen HD, Jørgensen LM, Keller SH, Andersen FL, Petersen IN, Knudsen GM, Svarer C. Automatic delineation of brain regions on MRI and PET images from the pig. J Neurosci Methods. 2018 Jan 15;294:51-58
• Wickham J, Brödjegård NG, Vighagen R, Pinborg LH, Bengzon J, Woldbye DPD, Kokaia M, Andersson M. Prolonged life of human acute hippocampal slices from temporal lobe epilepsy surgery. Sci Rep. 2018 Mar 7;8(1):4158
• Younis S, Hougaard A, Christensen CE, Vestergaard MB, Petersen ET, Paulson OB, Larsson HBW, Ashina M. Effects of sildenafil and calcitonin gene-related peptide on brainstem glutamate levels: a pharmacological proton magnetic resonance spectroscopy study at 3.0 T. J Headache Pain. 2018 Jun 18;19(1):44
• Østergaard L, Jørgensen MB, Knudsen GM. Low on Energy? An energy supply-demand perspective on stress and depression. Neurosci Biobehav Rev. 2018 Nov;94:248-270

• Herth MM, Knudsen GM. PET Imaging of the 5-HT2A Receptor System: A Tool to Study the Receptor’s In Vivo Brain Function. In: Guiard BP, Di Giovanni G. (Eds.). 5HT2A Receptors in the Central Nervous System. The Receptors, Vol. 32. Springer International Publishing, New York (USA). ISBN: 9783319704722

2017

• Beliveau V, Ganz M, Feng L, Ozenne B, Højgaard L, Fisher PM, Svarer C, Greve DN, Knudsen GM. A High-Resolution In Vivo Atlas of the Human Brain's Serotonin System. J Neurosci. 2017 Jan 4;37(1):120-128
• Celicanin M, Blaabjerg M, Maersk-Moller C, Beniczky S, Marner L, Thomsen C, Back FW, Kondziella D, Andersen H, Somnier F, Illes Z, Pinborg LH. Autoimmune encephalitis associated with voltage-gated potassium channels-complex and leucine-rich glioma-inactivated 1 antibodies - a national cohort study. Eur J Neurol. 2017 Aug;24(8):999-1005
• da Cunha-Bang S, Fisher PM, Hjordt LV, Perfalk E, Persson Skibsted A, Bock C, Ohlhues Baandrup A, Deen M, Thomsen C, Sestoft DM, Knudsen GM. Violent offenders respond to provocations with high amygdala and striatal reactivity. Soc Cogn Affect Neurosci. 2017 May 1;12(5):802-810
• da Cunha-Bang S, Hjordt LV, Perfalk E, Beliveau V, Bock C, Lehel S, Thomsen C, Sestoft D, Svarer C, Knudsen GM. Serotonin 1B receptor binding is associated with trait anger and level of psychopathy in violent offenders. Biol Psychiatry. 2017 Aug 15;82(4):267-274
• da Cunha-Bang S, Hjordt LV, Dam VH, Stenbæk DS, Sestoft D, Knudsen GM. Anterior cingulate serotonin 1B receptor binding is associated with emotional response inhibition. J Psychiatr Res. 2017 Sep;92:199-204
• Deen M, Christensen CE, Hougaard A, Hansen HD, Knudsen GM, Ashina M. Serotonergic mechanisms in the migraine brain - a systematic review. Cephalalgia. 2017 Mar;37(3):251-264
• Dickson JC, Tossici-Bolt L, Sera T, Booij J, Ziebell M, Morbelli S, Assenbaum-Nan S, Borght TV, Pagani M, Kapucu OL, Hesse S, Van Laere K, Darcourt J, Varrone A, Tatsch K. The impact of reconstruction and scanner characterisation on the diagnostic capability of a normal database for [123I]FP-CIT SPECT imaging. EJNMMI Res. 2017 Dec;7(1):10
• Edgar FG, Hansen HD, Leth-Petersen S, Ettrup A, Kristensen JL, Knudsen GM, Herth MM. Synthesis, radiofluorination and preliminary evaluation of the potential 5-HT2A receptor agonists [18 F]Cimbi-92 and [18 F]Cimbi-150. J Labelled Comp Radiopharm. 2017 Oct;60(12):586-591
• Feng L, Jensen P, Thomsen G, Dyssegaard A, Svarer C, Knudsen LV, Møller K, Thomsen C, Mikkelsen JD, Guilloteau D, Knudsen GM, Pinborg LH. The variability of translocator protein signal in brain and blood of genotyped healthy humans using in vivo 123I-CLINDE SPECT imaging - a test-retest study. J Nucl Med. 2017 Jun;58(6):989-995
• Fisher PM, Larsen CB, Beliveau V, Henningsson S, Pinborg A, Holst KK, Jensen PS, Svarer C, Siebner HR, Knudsen GM, Frokjaer VG. Pharmacologically Induced Sex Hormone Fluctuation Effects on Resting-State Functional Connectivity in a Risk Model for Depression: A Randomized Trial. Neuropsychopharmacology. 2017 Jan;42(2):446-453
• Fisher PM, Ozenne B, Svarer C, Adamsen D, Lehel S, Baaré WF, Jensen PS, Knudsen GM. BDNF val66met association with serotonin transporter binding in healthy humans. Transl Psychiatry. 2017 Feb 14;7(2):e1029
• Foged MT, Lindberg U, Vakamudi K, Larsson HBW, Pinborg LH, Kjær TW, Fabricius M, Svarer C, Ozenne B, Thomsen C, Beniczky S, Paulson OB, Posse S. Safety and EEG data quality of concurrent high-density EEG and high-speed fMRI at 3 Tesla. PLoS One. 2017 May 26;12(5):e0178409
• Ganz M, Feng L, Hansen HD, Beliveau V, Svarer C, Knudsen GM, Greve DN. Cerebellar heterogeneity and its impact on PET data quantification of 5-HT receptor radioligands. J Cereb Blood Flow Metab. 2017 Sep;37(9):3243-3252
• Ganz M, Kondermann D, Andrulis J, Knudsen GM, Maier-Hein L. Crowdsourcing for error detection in cortical surface delineations. Int J Comput Assist Radiol Surg. 2017 Jan;12(1):161-166
• Hansen HD, Mandeville JB, Sander CY, Hooker JM, Catana C, Rosen BR, Knudsen GM. Functional characterization of 5-HT1B receptor drugs in nonhuman primates using simultaneous PET-MR. J Neurosci. 2017 Nov 1;37(44):10671-10678
• Hansen HH, Weikop P, Mikkelsen MD, Rode F, Mikkelsen JD. The pan-Kv7 (KCNQ) Channel Opener Retigabine Inhibits Striatal Excitability by Direct Action on Striatal Neurons In Vivo. Basic Clin Pharmacol Toxicol. 2017 Jan;120(1):46-51
• Henningsen JB, Ancel C, Mikkelsen JD, Gauer F, Simonneaux V. Roles of RFRP-3 in the daily and seasonal regulation of reproductive activity in female Syrian hamsters. Endocrinology. 2017 Mar 1;158(3):652-663
• Hjordt LV, Stenbæk DS, Madsen KS, Mc Mahon B, Jensen CG, Vestergaard M, Hageman I, Meder D, Hasselbalch SG, Knudsen GM. State-dependent alterations in inhibitory control and emotional face identification in seasonal affective disorder. J Abnorm Psychol. 2017 Apr;126(3):291-300
• Hjordt LV, Stenbæk DS, Ozenne B, Mc Mahon B, Hageman I, Hasselbalch SG, Knudsen GM. Season-independent cognitive deficits in seasonal affective disorder and their relation to depressive symptoms. Psychiatry Res. 2017 Jul 30;257:219-226
• Jennings KJ, Chasles M, Cho H, Mikkelsen J, Bentley G, Keller M, Kriegsfeld LJ. The Preoptic Area and the RFamide-Related Peptide Neuronal System Gate Seasonal Changes in Chemosensory Processing. Integr Comp Biol. 2017 Nov 1;57(5):1055-1065
• Jensen CH, Hansen HD, Bay T, Vogensen SB, Lehel S, Thiesen L, Bundgaard C, Clausen RP, Knudsen GM, Herth MM, Wellendorph P, Frølund B. Radiosynthesis and Evaluation of [11C]3-Hydroxycyclopent-1-enecarboxylic Acid as Potential PET Ligand for the High-Affinity γ-Hydroxybutyric Acid Binding Sites. ACS Chem Neurosci. 2017 Jan 18;8(1):22-27
• Jørgensen LM, Weikop P, Villadsen J, Visnapuu T, Ettrup A, Hansen HD, Baandrup AO, Andersen FL, Bjarkam CR, Thomsen C, Jespersen B, Knudsen GM. Cerebral 5-HT release correlates with [11C]Cimbi36 PET measures of 5-HT2A receptor occupancy in the pig brain. J Cereb Blood Flow Metab. 2017 Feb;37(2):425-434
• Jørgensen LM, Piil K, Bashir A, Larsen MB, Poggenborg PS, Bjørck S, Fugleholm K. Is one-stop surgery for carpal tunnel syndrome safe? A retrospective long-term follow-up study in a neurosurgical unit in Copenhagen. BMJ Open. 2017 Sep 25;7(9):e016103
• Kessing LV, Munkholm K, Faurholt-Jepsen M, Miskowiak KW, Nielsen LB, Frikke-Schmidt R, Ekstrøm C, Winther O, Pedersen BK, Poulsen HE, McIntyre RS, Kapczinski F, Gattaz WF, Bardram J, Frost M, Mayora O, Knudsen GM, Phillips M, Vinberg M. The Bipolar Illness Onset study - research protocol for the BIO cohort study. BMJ Open. 2017 Jun 23;7(6):e015462
• Kondziella D, Fisher PM, Larsen VA, Hauerberg J, Fabricius M, Møller K, Knudsen GM. Functional MRI for Assessment of the Default Mode Network in Acute Brain Injury. Neurocrit Care. 2017 Dec;27(3):401-406
• Lauritzen MH, Magnusson P, Laustsen C, Butt SA, Ardenkjær-Larsen JH, Søgaard LV, Paulson OB, Åkeson P. Imaging Regional Metabolic Changes in the Ischemic Rat Heart In Vivo Using Hyperpolarized [1-13C]Pyruvate. Tomography. 2017 Sep;3(3):123-130
• Midttun M, Azad BB, Broholm R, Jensen LT, Svarer C, Jensen PE. Heat-washout measurements compared to distal blood pressure and perfusion in orthopaedic patients with foot ulcers. Clin Physiol Funct Imaging. 2017 Jan;37(1):79-83
• Miskowiak KW, Kessing LV, Ott CV, Macoveanu J, Harmer CJ, Jørgensen A, Revsbech R, Jensen HM, Paulson OB, Siebner HR, Jørgensen MB. Does a single session of electroconvulsive therapy alter the neural response to emotional faces in depression? A randomised sham-controlled functional magnetic resonance imaging study. J Psychopharmacol. 2017 Sep;31(9):1215-1224
• Nørbak-Emig H, Pinborg LH, Raghava JM, Svarer C, Baaré WFC, Allerup P, Friberg L, Rostrup E, Glenthøj B, Ebdrup BH. Extrastriatal dopamine D2/3 receptors and cortical grey matter volumes in antipsychotic-naïve schizophrenia patients before and after initial antipsychotic treatment. World J Biol Psychiatry. 2017 Oct;18(7):539-549
• Nørgaard M, Ganz M, Svarer C, Fisher PM, Churchill NW, Beliveau V, Grady C, Strother SC, Knudsen GM. Brain Networks Implicated in Seasonal Affective Disorder: A Neuroimaging PET Study of the Serotonin Transporter. Front Neurosci. 2017 Nov 3;11:614
• Olsen AS, Steensberg AT, la Cour M, Kjaer TW, Damato B, Pinborg LH, Kolko M. Can DMCO Detect Visual Field Loss in Neurological Patients? A Secondary Validation Study. Ophthalmic Res. 2017;58(2):85-93
• Perfalk E, Cunha-Bang SD, Holst KK, Keller S, Svarer C, Knudsen GM, Frokjaer VG. Testosterone levels in healthy men correlate negatively with serotonin 4 receptor binding. Psychoneuroendocrinology. 2017 Mar 22;81:22-28
• Petersen IN, Villadsen J, Hansen HD, Madsen J, Jensen AA, Gillings N, Lehel S, Herth MM, Knudsen GM, Kristensen JL. 18F-Labelling of electron rich iodonium ylides: application to the radiosynthesis of potential 5-HT2A receptor PET ligands. Org Biomol Chem. 2017 May 23;15(20):4351-4358
• Rasmussen JH, Nørgaard M, Hansen AE, Vogelius IR, Aznar MC, Johannesen HH, Costa J, Engberg AM, Kjær A, Specht L, Fischer BM. Feasibility of Multiparametric Imaging with PET/MR in Head and Neck Squamous Cell Carcinoma. J Nucl Med. 2017 Jan;58(1):69-74
• Skibsted AP, Cunha-Bang SD, Carré JM, Hansen AE, Beliveau V, Knudsen GM, Fisher PM. Aggression-related brain function assessed with the Point Subtraction Aggression Paradigm in fMRI. Aggress Behav. 2017 Nov;43(6):601-610
• Stéen EJ, Nyberg N, Lehel S, Andersen VL, Di Pilato P, Knudsen GM, Kristensen JL, Herth MM. Development of a simple proton nuclear magnetic resonance-based procedure to estimate the approximate distribution coefficient at physiological pH (logD7.4): Evaluation and comparison to existing practices. Bioorg Med Chem Lett. 2017 Jan 15;27(2):319-322
• Stenbæk DS, Fisher PM, Ozenne B, Andersen E, Hjordt LV, McMahon B, Hasselbalch SG, Frokjaer VG, Knudsen GM. Brain serotonin 4 receptor binding is inversely associated with verbal memory recall. Brain Behav. 2017 Mar 17;7(4):e00674
• Stenbæk DS, Dam VH, Fisher PM, Hansen N, Hjordt LV, Frøkjær VG. No evidence for a role of the serotonin 4 receptor in five-factor personality traits: A positron emission tomography brain study. PLoS One. 2017 Sep 7;12(9):e0184403
• Tossici-Bolt L, Dickson JC, Sera T, Booij J, Asenbaun-Nan S, Bagnara MC, Borght TV, Jonsson C, de Nijs R, Hesse S, Koulibaly PM, Akdemir UO, Koole M, Tatsch K, Varrone A. [123I]FP-CIT ENC-DAT normal database: the impact of the reconstruction and quantification methods. EJNMMI Phys. 2017 Dec;4(1):8
• Tuominen L, Miettunen J, Cannon DM, Drevets WC, Frokjaer VG, Hirvonen J, Ichise M, Jensen PS, Keltikangas-Järvinen L, Klaver JM, Knudsen GM, Takano A, Suhara T, Hietala J. Neuroticism associates with cerebral in vivo serotonin transporter binding differently in males and females. Int J Neuropsychopharmacol. 2017 Dec 1;20(12):963-970
• Vestergaard M, Holm SK, Uldall P, Siebner HR, Paulson OB, Baaré WFC, Madsen KS. Glucocorticoid treatment earlier in childhood and adolescence show dose-response associations with diurnal cortisol levels. Dev Psychobiol. 2017 Dec;59(8):1010-1020
• Wichern F, Jensen MM, Christensen DZ, Mikkelsen JD, Gondré-Lewis MC, Thomsen MS. Perinatal nicotine treatment induces transient increases in NACHO protein levels in the rat frontal cortex. Neuroscience. 2017 Jan 25;346:278-283
• Yang KC, Stepanov V, Martinsson S, Ettrup A, Takano A, Knudsen GM, Halldin C, Farde L, Finnema SJ. Fenfluramine Reduces [11C]Cimbi-36 Binding to the 5-HT2A Receptor in the Nonhuman Primate Brain. Int J Neuropsychopharmacol. 2017 Sep 1;20(9):683-691

2016

• Albert NL, Unterrainer M, Diemling M, Xiong G, Bartenstein P, Koch W, Varrone A, Dickson JC, Tossici-Bolt L, Sera T, Asenbaum S, Booij J, Kapucu LÖ, Kluge A, Ziebell M, Darcourt J, Nobili F, Pagani M, Sabri O, Hesse S, Borght TV, Van Laere K, Tatsch K, la Fougère C. Implementation of the European multicentre database of healthy controls for [(123)I]FP-CIT SPECT increases diagnostic accuracy in patients with clinically uncertain parkinsonian syndromes. Eur J Nucl Med Mol Imaging. 2016 Jul;43(7):1315-22
• Andersson M, Avaliani N, Svensson A, Wickham J, Pinborg LH, Jespersen B, Christiansen SH, Bengzon J, Woldbye DP, Kokaia M. Optogenetic control of human neurons in organotypic brain cultures. Sci Rep. 2016 Apr 21;6:24818
• Arvaniti M, Jensen MM, Soni N, Wang H, Klein AB, Thiriet N, Pinborg LH, Muldoon PP, Wienecke J, Imad Damaj M, Kohlmeier KA, Gondré-Lewis MC, Mikkelsen JD, Thomsen MS. Functional interaction between Lypd6 and nicotinic acetylcholine receptors. J Neurochem. 2016 Sep;138(6):806-20
• Beniczky S, Duez L, Scherg M, Hansen PO, Tankisi H, Sidenius P, Sabers A, Pinborg LH, Uldall P, Fuglsang-Frederiksen A. Visualizing spikes in source-space: Rapid and efficient evaluation of magnetoencephalography. Clin Neurophysiol. 2016 Feb;127(2):1067-72
• Blomster LV, Strøbaek D, Hougaard C, Klein J, Pinborg LH, Mikkelsen JD, Christophersen P. Quantification of the functional expression of the Ca2+ -activated K+ channel KCa 3.1 on microglia from adult human neocortical tissue. Glia. 2016 Dec;64(12):2065-2078
• Bortz DM, Upton BA, Mikkelsen JD, Bruno JP. Positive allosteric modulators of the α7 nicotinic acetylcholine receptor potentiate glutamate release in the prefrontal cortex of freely-moving rats. Neuropharmacology. 2016 Dec;111:78-91
• Buchert R, Kluge A, Tossici-Bolt L, Dickson J, Bronzel M, Lange C, Asenbaum S, Booij J, Atay Kapucu LÖ, Svarer C, Koulibaly PM, Nobili F, Pagani M, Sabri O, Sera T, Tatsch K, Vander Borght T, Van Laere K, Varrone A, Iida H. Reduction in camera-specific variability in [123I]FP-CIT SPECT outcome measures by image reconstruction optimized for multisite settings: impact on age-dependence of the specific binding ratio in the ENC-DAT database of healthy controls. Eur J Nucl Med Mol Imaging. 2016 Jul;43(7):1323-36
• da Cunha-Bang S, Mc Mahon B, MacDonald Fisher P, Jensen PS, Svarer C, Moos Knudsen G. High trait aggression in men is associated with low 5-HT levels, as indexed by 5-HT4 receptor binding. Soc Cogn Affect Neurosci. 2016 Apr;11(4):548-55
• Dam JH, Bender D, Peters D, Någren K. [(11)C]NS9531, [(11)C]NS9762 and [(11)C]NS6417, specific SERT tracers: pre-clinical evaluation in pigs and optimization of synthesis conditions using [(11)C]methyl triflate. Nucl Med Biol. 2016 Jan;43(1):42-51
• Dogonowski AM, Blinkenberg M, Paulson OB, Sellebjerg F, Sørensen PS, Siebner HR, Madsen KH. Recovery from an acute relapse is associated with changes in motor resting-state connectivity in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2016 Aug;87(8):912-4
• Donat CK, Gaber K, Meixensberger J, Brust P, Pinborg LH, Hansen HH, Mikkelsen JD. Changes in Binding of [123I]CLINDE, a High-Affinity Translocator Protein 18 kDa (TSPO) Selective Radioligand in a Rat Model of Traumatic Brain Injury. Neuromolecular Med. 2016 Jun;18(2):158-69
• Ettrup A, Svarer C, McMahon B, da Cunha-Bang S, Lehel S, Møller K, Dyssegaard A, Ganz M, Beliveau V, Jørgensen LM, Gillings N, Knudsen GM. Serotonin 2A receptor agonist binding in the human brain with [(11)C]Cimbi-36: Test-retest reproducibility and head-to-head comparison with the antagonist [(18)F]altanserin. Neuroimage. 2016 Apr 15;130:167-74
• Feng L, Svarer C, Madsen K, Ziebell M, Dyssegaard A, Ettrup A, Hansen HD, Lehel S, Yndgaard S, Paulson OB, Knudsen GM, Pinborg LH. Design of Infusion Schemes for Neuroreceptor Imaging: Application to [11C]Flumazenil-PET Steady-State Study. Biomed Res Int. 2016;2016:9132840
• Greve DN, Salat DH, Bowen SL, Izquierdo-Garcia D, Schultz AP, Catana C, Becker JA, Svarer C, Knudsen G, Sperling RA, Johnson KA. Different partial volume correction methods lead to different conclusions: An 18F-FDG-PET study of aging. Neuroimage. 2016 May 15;132:334-43
• Hansen HH, Fabricius K, Barkholt P, Mikkelsen JD, Jelsing J, Pyke C, Knudsen LB, Vrang N. Characterization of liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in rat partial and full nigral 6-hydroxydopamine lesion models of Parkinson's disease. Brain Res. 2016 Sep 1;1646:354-65
• Henningsen JB, Poirel VJ, Mikkelsen JD, Tsutsui K, Simonneaux V, Gauer F. Sex differences in the photoperiodic regulation of RF-amide related peptide (RFRP) and its receptor GPR147 in the Syrian hamster. J Comp Neurol. 2016 Jun 15;524(9):1825-38
• Herth MM, Petersen IN, Hansen HD, Hansen M, Ettrup A, Jensen AA, Lehel S, Dyssegaard A, Gillings N, Knudsen GM, Kristensen JL. Synthesis and evaluation of 18F-labeled 5-HT2A receptor agonists as PET ligands. Nucl Med Biol. 2016 Apr 19;43(8):455-462
• Hervig ME, Thomsen MS, Kalló I, Mikkelsen JD. Acute phencyclidine administration induces c-Fos-immunoreactivity in interneurons in cortical and subcortical regions. Neuroscience. 2016 Oct 15;334:13-25
• Jakobsen GR, Fisher PM, Dyssegaard A, McMahon B, Holst KK, Lehel S, Svarer C, Jensen PS, Knudsen GM, Frokjaer VG. Brain serotonin 4 receptor binding is associated with the cortisol awakening response. Psychoneuroendocrinology. 2016 May;67:124-32
• Jensen CG, Niclasen J, Vangkilde SA, Petersen A, Hasselbalch SG. General Inattentiveness Is a Long-Term Reliable Trait Independently Predictive of Psychological Health: Danish Validation Studies of the Mindful Attention Awareness Scale. Psychol Assess. 2016 May;28(5):e70-87
• Jensen CG, Hjordt LV, Stenbæk DS, Andersen E, Back SK, Lansner J, Hageman I, Dam H, Nielsen AP, Knudsen GM, Frokjaer VG, Hasselbalch SG. Development and Psychometric Validation of the Verbal Affective Memory Test. Memory. 2016 Oct;24(9):1208-23
• Jorgensen A, Magnusson P, Hanson LG, Kirkegaard T, Benveniste H, Lee H, Svarer C, Mikkelsen JD, Fink-Jensen A, Knudsen GM, Paulson OB, Bolwig TG, Jorgensen MB. Regional brain volumes, diffusivity, and metabolite changes after electroconvulsive therapy for severe depression. Acta Psychiatrica Scandinavica. 2016 Feb 3;133(2):154-164
• Klein AB, Bay T, Villumsen IS, Falk-Petersen CB, Marek A, Frølund B, Clausen RP, Hansen HD, Knudsen GM, Wellendorph P. Autoradiographic imaging and quantification of the high-affinity GHB binding sites in rodent brain using 3H-HOCPCA. Neurochem Int. 2016 Sep 8;100:138-145
• Knudsen GM, Jensen PS, Erritzoe D, Baaré WFC, Ettrup A, Fisher PM, Gillings N, Hansen HD, Hansen LK, Hasselbalch SG, Henningsson S, Herth MM, Holst KK, Iversen P, Kessing LV, Macoveanu J, Madsen KS, Mortensen EL, Nielsen FÅ, Paulson OB, Siebner HR, Stenbæk DS, Svarer C, Jernigan TL, Strother SC, Frokjaer VG. The Center for Integrated Molecular Brain Imaging (Cimbi) Database. NeuroImage. 2016 Jan 1;124(Pt B):1213-1219
• Kondziella D, Friberg CK, Frokjaer VG, Fabricius M, Møller K. Preserved consciousness in vegetative and minimal conscious states: systematic review and meta-analysis. J Neurol Neurosurg Psychiatry. 2016 May;87(5):485-92
• Larsen IU, Mortensen EL, Vinther-Jensen T, Nielsen JE, Knudsen GM, Vogel A. Personality traits in Huntington's disease: An exploratory study of gene expansion carriers and non-carriers. Am J Med Genet B Neuropsychiatr Genet. 2016 Dec;171(8):1153-1160
• Laursen HR, Henningsson S, Macoveanu J, Jernigan TL, Siebner HR, Holst KK, Skimminge A, Knudsen GM, Ramzøy TZ, Erritzoe D. Serotonergic neurotransmission in emotional processing: New evidence from long-term recreational poly-drug ecstasy use. J Psychopharmacol. 2016 Dec;30(12):1296-1304
• Leth-Petersen S, Gabel-Jensen C, Gillings N, Lehel S, Hansen HD, Knudsen GM, Kristensen JL. Metabolic fate of hallucinogenic NBOMes. Chem Res Toxicol. 2016 Jan 19;29(1):96-100
• Lyukmanova EN, Shulepko MA, Kudryavtsev D, Bychkov ML, Kulbatskii DS, Kasheverov IE, Astapova MV, Feofanov AV, Thomsen MS, Mikkelsen JD, Shenkarev ZO, Tsetlin VI, Dolgikh DA, Kirpichnikov MP. Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of α7 Nicotinic Acetylcholine Receptor. PLoS One. 2016 Feb 23;11(2):e0149733
• Macoveanu J, Henningsson S, Pinborg A, Jensen PS, Knudsen GM, Frokjaer VG, Siebner HR. Sex-Steroid Hormone Manipulation Reduces Brain Response to Reward. Neuropsychopharmacology. 2016 Mar;41(4):1057-65
• Macoveanu J, Fisher PM, Madsen MK, Mc Mahon B, Knudsen GM, Siebner HR. Bright-light intervention induces a dose-dependent increase in striatal response to risk in healthy volunteers. Neuroimage. 2016 Jun 16;139:37-43
• Madsen MK, Mc Mahon B, Andersen SB, Siebner HR, Knudsen GM, Fisher PM. Threat-related amygdala functional connectivity is associated with 5-HTTLPR genotype and neuroticism. Soc Cogn Affect Neurosci. 2016 Jan;11(1):140-9
• Mandeville JB, Sander CY, Wey HY, Hooker JM, Hansen HD, Svarer C, Knudsen GM, Rosen BR. A regularized full reference tissue model for PET neuroreceptor mapping. Neuroimage. 2016 Jun 27;139:405-414
• Mc Mahon B, Andersen SB, Madsen MK, Hjordt LV, Hageman I, Dam H, Svarer C, da Cunha-Bang S, Baaré W, Madsen J, Hasholt L, Holst K, Frokjaer VG, Knudsen GM. Seasonal difference in brain serotonin transporter binding predicts symptom severity in patients with seasonal affective disorder. Brain. 2016 May;139(Pt 5):1605-14
• Miskowiak KW, Vinberg M, Glerup L, Paulson OB, Knudsen GM, Ehrenreich H, Harmer CJ, Kessing LV, Siebner HR, Macoveanu J. Neural correlates of improved executive function following erythropoietin treatment in mood disorders. Psychol Med. 2016 Jun;46(8):1679-91
• Miskowiak KW, Macoveanu J, Vinberg M, Assentoft E, Randers L, Harmer CJ, Ehrenreich H, Paulson OB, Knudsen GM, Siebner HR, Kessing LV. Effects of erythropoietin on memory-relevant neurocircuitry activity and recall in mood disorders. Acta Psychiatr Scand. 2016 Sep;134(3):249-59
• Nørbak-Emig H, Ebdrup BH, Fagerlund B, Svarer C, Rasmussen H, Friberg L, Allerup PN, Rostrup E, Pinborg LH, Glenthøj BY. Frontal D2/3 receptor availability in schizophrenia patients before and after their first antipsychotic treatment: Relation to cognitive functions and psychopathology. Int J Neuropsychopharmacol. 2016 Apr 29;19(5)
• Palner M, Beinat C, Banister S, Zanderigo F, Park JH, Shen B, Hjoernevik T, Jung JH, Lee BC, Kim SE, Fung L, Chin FT. Effects of common anesthetic agents on [18F]flumazenil binding to the GABAA Receptor. EJNMMI Res. 2016 Dec;6(1):80
• Petersen IN, Villadsen J, Hansen HD, Jensen AA, Lehel S, Gillings N, Herth MM, Knudsen GM, Kristensen JL. Convergent 18F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands. Bioorg Med Chem. 2016 Nov 1;24(21):5353-5356
• Rasmussen H, Frokjaer VG, Hilker RW, Madsen J, Anhøj S, Oranje B, Pinborg LH, Glenthøj B, Knudsen GM. Low frontal serotonin 2A receptor binding is a state marker for schizophrenia?  Eur Neuropsychopharmacol. 2016 Jul;26(7):1248-50
• Rötering S, Scheunemann M, Günther R, Löser R, Hiller A, Peters D, Brust P, Fischer S, Steinbach J. Tos-Nos-Mos: Synthesis of different aryl sulfonate precursors for the radiosynthesis of the alpha7 nicotinic acetylcholine receptor radioligand [18F]NS14490. Appl Radiat Isot. 2016 Apr 28;114:57-62
• Salaga M, Blomster LV, Piechota-Polańczyk A, Zielińska M, Jacenik D, Cygankiewicz AI, Krajewska WM, Mikkelsen JD, Fichna J. Encenicline, an α7 Nicotinic Acetylcholine Receptor Partial Agonist, Reduces Immune Cell Infiltration in the Colon and Improves Experimental Colitis in Mice. J Pharmacol Exp Ther. 2016 Jan;356(1):157-69
• Stenbæk DS, Einarsdottir HS, Goregliad-Fjeallingsdal T, Knudsen GM, Frokjaer VG, Hasselbalch SG. Evaluation of acute tryptophan depletion and sham depletion with a gelatin-based collagen peptide protein mixture. Eur Neuropsychopharmacol. 2016 Jan;26(1):147-9
• Stenbæk DS, Fisher PM, Budtz-Jørgensen E, Pinborg A, Hjordt LV, Jensen PS, Knudsen GM, Frokjaer VG. Sex hormone manipulation slows reaction time and increases labile mood in healthy women. Psychoneuroendocrinology. 2016 Jun;68:39-46
• Thomsen MS, Arvaniti M, Jensen MM, Shulepko MA, Dolgikh DA, Pinborg LH, Härtig W, Lyukmanova EN, Mikkelsen JD. Lynx1 and Aβ1-42 bind competitively to multiple nicotinic acetylcholine receptor subtypes. Neurobiol Aging. 2016 Oct;46:13-21
• Vedel AG, Holmgaard F, Rasmussen LS, Paulson OB, Thomsen C, Danielsen ER, Langkilde A, Goetze JP, Lange T, Ravn HB, Nilsson JC. Perfusion Pressure Cerebral Infarct (PPCI) trial - the importance of mean arterial pressure during cardiopulmonary bypass to prevent cerebral complications after cardiac surgery: study protocol for a randomised controlled trial. Trials. 2016 May 17;17(1):247
• Wu J, Liu Q, Tang P, Mikkelsen JD, Shen J, Whiteaker P, Yakel JL. Heteromeric α7β2 Nicotinic Acetylcholine Receptors in the Brain. Trends Pharmacol Sci. 2016 Jul;37(7):562-74

2015

• Andersen VL, Hansen HD, Herth MM, Dyssegaard A, Knudsen GM, Kristensen JL. (11)C-labeling and preliminary evaluation of pimavanserin as a 5-HT2A receptor PET-radioligand. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1053-6
• Asghar Butt S, Søgaard LV, Ardenkjaer-Larsen JH, Lauritzen MH, Engelholm LH, Paulson OB, Mirza O, Holck S, Magnusson P, Akeson P. Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-13 C]pyruvate. Magn Reson Med. 2015 Jan;73(1):51-8
• Beliveau V, Svarer C, Frokjaer VG, Knudsen GM, Greve DN, Fisher PM. Functional connectivity of the dorsal and median raphe nuclei at rest. Neuroimage. 2015 Aug 1;116:187-95
• Bertelsen B, Oranje B, Melchior L, Fagerlund B, Werge TM, Mikkelsen JD, Tümer Z, Glenthøj BY. Association Study of CHRNA7 Promoter Variants with Sensory and Sensorimotor Gating in Schizophrenia Patients and Healthy Controls: A Danish Case-Control Study. Neuromolecular Med. 2015 Dec;17(4):423-30
• Blaabjerg M, Mærsk-Møller CC, Kondziella D, Somnier F, Celicanin M, Andersen H, Bach FW, Pinborg LH. Workup and treatment of autoimmune encephalitis. Ugeskr Laeger. 2015 Nov 2;177(45)
• Boutin H, Pinborg LH. TSPO imaging in stroke: from animal models to human subjects. Clin Transl Imaging. 2015 Dec;3(6):423-35
• Bruun M, Hjermind LE, Thomsen C, Danielsen E, Thomsen LL, Pinborg LH, Khabbazbavani N, Nielsen JE. Familial hemiplegic migraine type 1 associated with parkinsonism: a case report. Case Rep Neurol. 2015 Apr 14;7(1):84-9
• Fisher PM, Holst KK, Adamsen D, Klein AB, Frokjaer VG, Jensen PS, Svarer C, Gillings N, Baare WFC, Mikkelsen JD, Knudsen GM. BDNF val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. Hum Brain Mapp. 2015 Jan;36(1):313-23
• Fisher PM, Haahr ME, Jensen CG, Frokjaer VG, Siebner HR, Knudsen GM. Fluctuations in [11C]SB207145 PET binding associated with change in threat-related amygdala reactivity in humans. Neuropsychopharmacology. 2015 May;40(6):1510-8
• Fisher PM, Grady CL, Madsen MK, Strother SC, Knudsen GM. 5-HTTLPR differentially predicts brain network responses to emotional faces. Hum Brain Mapp. 2015 Jul;36(7):2842-51
• Frimer NA, Overgaard A, Lie MEK, Mikkelsen JD, Frokjaer VG. Ovariectomy drives asynchronous changes in serotonin receptor 2A and transporter availability in rats. J Steroids Horm Sci. 2015 Nov; 6: 161
• Frokjaer VG, Pinborg A, Holst KK, Overgaard A, Henningsson S, Heede M, Larsen EC, Jensen PS, Agn M, Nielsen AP, Stenbæk DS, da Cunha-Bang S, Lehel S, Siebner HR, Mikkelsen JD, Svarer C, Knudsen GM. Role of Serotonin Transporter Changes in Depressive Responses to Sex-Steroid Hormone Manipulation: A Positron Emission Tomography Study. Biol Psychiatry. 2015 Oct 15;78(8):534-43
• Ganz M, Greve DN, Fischl B, Konukoglu E, for the Alzheimer’s Disease Neuroimaging Initiative. Relevant Feature Set Estimation with a Knock-out Strategy and Random Forests. NeuroImage. 2015 Aug 10;122:131-148
• Hansen HD, Andersen VL, Lehel S, Magnussen JH, Dyssegaard A, Stroth N, Kristensen JL, Knudsen GM, Herth MM. Labeling and preliminary in vivo evaluation of the 5-HT7 receptor selective agonist [(11)C]E-55888. Bioorg Med Chem Lett. 2015 May 1;25(9):1901-4
• Henningsson S, Madsen KH, Pinborg A, Heede M, Knudsen GM, Siebner HR, Frokjaer VG. Role of emotional processing in depressive responses to sex-hormone manipulation: a pharmacological fMRI study. Transl Psychiatry. 2015 Dec 1;5:e688
• Herth MM, Andersen VL, Hansen HD, Stroth N, Volk B, Lehel S, Dyssegaard A, Ettrup A, Svenningsson P, Knudsen GM, Kristensen JL. Evaluation of 3-Ethyl-3-(phenylpiperazinylbutyl)oxindoles as PET Ligands for the Serotonin 5-HT7 Receptor: Synthesis, Pharmacology, Radiolabeling, and in Vivo Brain Imaging in Pigs. J Med Chem. 2015 Apr 23;58(8):3631-6
• Herth M, Knudsen GM. Current Radiosynthesis Strategies for 5-HT2A Receptor PET Tracers. J Labelled Comp Radiopharm. 2015 Jun 15;58(7):265-73
• Holm SK, Vestergaard M, Madsen KS, Baaré WF, Hammer TB, Born AP, Siebner HR, Paulson OB, Uldall PV. Children and adolescents previously treated with glucocorticoids display lower verbal intellectual abilities. Acta Paediatr. 2015 Aug;104(8):784-91
• Haahr ME, Hansen DL, Fisher PM, Svarer C, Stenbæk D, Madsen K, Madsen J, Holst JJ, Baaré WF, Hojgaard L, Almdahl T, Knudsen GM. Central 5-HT neurotransmission modulates weight loss following gastric bypass surgery in obese individuals. J Neurosci. 2015 Apr 8;35(14):5884-9
• Jansen WJ, Ossenkoppele R, Knol DL, Tijms BM, Scheltens P, Verhey FR, Visser PJ; Amyloid Biomarker Study Group. Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis. JAMA. 2015 May 19;313(19):1924-38
• Jensen CG, Lansner J, Petersen A, Vangkilde SA, Ringkøbing SP, Frokjaer VG, Adamsen D, Knudsen GM, Denninger JW, Hasselbalch SG. Open and Calm--a randomized controlled trial evaluating a public stress reduction program in Denmark. BMC Public Health. 2015 Dec 16;15:1245
• Jensen MM, Arvaniti M, Mikkelsen JD, Michalski D, Pinborg LH, Härtig W, Thomsen MS. Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease. Neurobiol Aging. 2015 Apr;36(4):1629-38
• Jensen P, Kondziella D, Thomsen G, Dyssegaard A, Svarer C, Pinborg LH. Anti-NMDAR encephalitis: demonstration of neuroinflammation and the effect of immunotherapy. Neurology. 2015 Feb 24;84(8):859
• Jensen P, Feng L, Law I, Svarer C, Knudsen GM, Mikkelsen JD, de Nijs R, Larsen VA, Dyssegaard A, Thomsen GK, Fischer W, Guilloteau D, Pinborg LH. TSPO imaging in glioblastoma multiforme: A direct comparison between 123I-CLINDE SPECT, 18F-FET PET and gadolinium-enhanced MRI. J Nucl Med. 2015 Sep;56(9):1386-90
• Jensen P, Meden P, Knudsen LV, Knudsen GM, Thomsen C, Feng L, Pinborg LH. [Golf handicap score is a suitable scale for monitoring rehabilitation after apoplexia cerebri]. Ugeskr Laeger. 2015 Dec 21;177(52)
• Jorgensen A, Hansen BS, Stanislaus S, Düring S, Jørgensen MB, Pinborg LH, Kondziella D. Anti-N-methyl-d-aspartate receptor encephalitis is an important differential diagnosis in acute psychiatric disease. Acta Psychiatr Scand. 2015 Jan;131(1):69-70
• Keller SH, Hansen C, Hansen C, Andersen FL, Ladefoged C, Svarer C, Kjær A, Højgaard L, Law I, Henriksen OM, Hansen AE. Motion correction in simultaneous PET/MR brain imaging using sparsely sampled MR navigators: a clinically feasible tool. EJNMMI Phys. 2015 Dec;2(1):14. Erratum in: EJNMMI Phys. 2015 Dec;2(1):23
• Ledri M, Sørensen AT, Madsen MG, Christiansen SH, Ledri LN, Cifra A, Bengzon J, Lindberg E, Pinborg LH, Jespersen B, Gøtzsche CR, Woldbye DP, Andersson M, Kokaia M. Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus. J Neurosci. 2015 Jul 1;35(26):9622-31
• Lunn TH, Frokjaer VG, Hansen TB, Kristensen PW, Lind T, Kehlet H. Analgesic Effect of Perioperative Escitalopram in High Pain Catastrophizing Patients after Total Knee Arthroplasty: A Randomized, Double-blind, Placebo-controlled Trial. Anesthesiology. 2015 Apr;122(4):884-94
• Madsen K, Torstensen E, Holst KK, Haahr ME, Knorr U, Frokjaer VG, Brandt-Larsen M, Iversen P, Fisher PM, Knudsen GM. Familial risk for major depression is associated with lower striatal 5-HT4 receptor binding. Int J Neuropsychopharmacol. 2015 Jan 1;18(1)
• Magnussen JH, Ettrup A, Donat CK, Peters D, Pedersen MHF, Knudsen GM, Mikkelsen JD. Radiosynthesis and in vitro validation of 3H-NS14492 as a novel high affinity alpha7 nicotinic receptor radioligand. Eur J Pharmacol. 2015 May 1; 762;35-41
• Miskowiak KW, Vinberg M, Macoveanu J, Ehrenreich H, Køster N, Inkster B, Paulson OB, Kessing LV, Skimminge A, Siebner HR. Effects of Erythropoietin on Hippocampal Volume and Memory in Mood Disorders. Biol Psychiatry. 2015 Aug 15;78(4)270-7
• Nalla AA, Thomsen G, Knudsen GM, Frokjaer VG. The effect of storage conditions on salivary cortisol concentrations using an Enzyme Immuno Assay. Scand J Clin Lab Invest. 2015 Jan;75(1):92-5
• Nørgaard M, Ganz M, Svarer C, Beliveau V, Fisher PM, Mc Mahon B, Greve DN, Strother SC, Knudsen GM. Estimation of Regional Seasonal Variations in SERT-levels using the FreeSurfer PET pipeline: a reproducibility study. Proceedings of the MICCAI workshop on Computational Methods for Molecular Imaging, 2015
• Ossenkoppele R, Jansen WJ, Rabinovici GD, Knol DL, van der Flier WM, van Berckel BN, Scheltens P, Visser PJ; Amyloid PET Study Group. Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis. JAMA. 2015 May 19;313(19):1939-49
• Overgaard A, Axel AM, Lie ME, Hansen HH, Mikkelsen JD. High plasma triglyceride levels strongly correlate with low kisspeptin in the arcuate nucleus of male rats. Endocr Regul. 2015;49(2):51-7
• Ratner C, Madsen AN, Kristensen LV, Skov LJ, Pedersen KS, Mortensen OH, Knudsen GM, Raun K, Holst B. Impaired oxidative capacity due to decreased CPT1b levels as a contributing factor to fat accumulation in obesity. Am J Physiol Regul Integr Comp Physiol. 2015 Jun 1;308(11):R973-82
• Spies M, Knudsen GM, Lanzenberger R, Kasper S. Investigating the Serotonin Transporter in Psychiatric Disorders: Insights from PET Imaging. Lancet Psychiatry. 2015 Aug;2(8):743-55
• Stenbæk DS, Toftager M, Hjordt LV, Jensen PS, Holst KK, Bryndorf T, Holland T, Bogstad J, Pinborg A, Horness P, Frokjaer VG. Mental distress and personality in women undergoing GnRH antagonist versus GnRH agonist protocols for assisted reproductive technology. Hum Reprod. 2015 Jan;30(1):103-10
• Teodoro R, Scheunemann M, Deuther-Conrad W, Wenzel B, Fasoli FM, Gotti C, Kranz M, Donat CK, Patt M, Hillmer A, Zheng MQ, Peters D, Steinbach J, Sabri O, Huang Y, Brust P. A Promising PET Tracer for Imaging of α7 Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand. Molecules. 2015 Oct 9;20(10):18387-18421
• Thomsen MS, Zwart R, Ursu D, Jensen MM, Pinborg LH, Gilmour G, Wu J, Sher E, Mikkelsen JD. α7 and β2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes that Are Expressed in the Human Cortex and Display Distinct Pharmacological Properties. PLoS One. 2015 Jun 18;10(6):e0130572
• Visser AK, Ettrup A, Klein AB, van Waarde A, Bosker FJ, Meerlo P, Knudsen GM, de Boer SF. Similar serotonin-2A receptor binding in rats with different coping styles or levels of aggression. Synapse. 2015 Apr;69(4):226-32
• Wulff S, Pinborg LH, Svarer C, Jensen LT, Nielsen MØ, Allerup P, Bak N, Rasmussen H, Frandsen E, Rostrup E, Glenthøj BY. Striatal D2/3 Binding Potential Values in Drug-Naïve First-Episode Schizophrenia Patients Correlate With Treatment Outcome. Schizophr Bull. 2015 Sep;41(5):1143-52

• Agn M, Svarer C, Frokjaer VG, Greve DN, Knudsen GM, Leemput KV. Improved Resolution and Reliability in Dynamic PET Using Bayesian Regularization of MRTM2. 2014 IEEE International Symposium on Biomedical Imaging
• Andersen SB, Holst KK, McMahon B, Madsen MK, Møller P, Hageman I, Knudsen GM. Sweet taste sensitivity is influenced by 5-HTTLPR genotype and affected in seasonal affective disorder. Psychiatry Research. 2014 Dec 15;220(1-2):727-9
• Andersen VL, Hansen HD, Herth MM, Knudsen GM, Kristensen JL. 11C-labeling and preliminary evaluation of vortioxetine as a PET radioligand. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2408-11
• Bartzen-Sprauer J, Klosen P, Ciofi P, Mikkelsen JD, Simonneaux V. Photoperiodic co-regulation of kisseptin, neurokinin B and dynorphin in the hypothalamus of a seasonal rodent. J Neuroendocrinol. 2014 Aug;26(8):510-20
• Bertelsen B, Melchior L, Tümer Z, Groth C, Mol Debes N, Skov L, Holst KK, Fagerlund B, Mikkelsen JD. Association of the CHRNA7 promoter variant -86T with Tourette syndrome and comorbid obsessive-compulsive disorder. Psychiatry Res. 2014 Nov 30;219(3):710-1
• Bortz DM, Jørgensen CV, Mikkelsen JD, Bruno JP. Transient inactivation of the ventral hippocampus in neonatal rats impairs the mesolimbic regulation of prefrontal glutamate release in adulthood. Neuropharmacology. 2014 Sep;84:19-30
• Brindisi M, Butini S, Franceschini S, Brogi S, Trotta F, Ros S, Cagnotto A, Salmona M, Casagni A, Andreassi M, Saponara S, Gorelli B, Weikop P, Mikkelsen JD, Scheel-Kruger J, Sandager-Nielsen K, Novellino E, Campiani G, Gemma S. Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: synthesis, biological characterization, and behavioral studies. J Med Chem. 2014 Nov 26;57(22):9578-97
• Comasco E, Frøkjær VG, Poromaa IS. Functional and molecular neuroimaging of menopause and hormone replacement therapy. Frontiers Neuroscience. 2014 Dec 8;8:388
• Dogonowski AM, Andersen KW, Madsen KH, Sørensen PS, Paulson OB, Blinkenberg M, Siebner HR. Multiple sclerosis impairs regional functional connectivity in the cerebellum. Neuroimage Clin. 2014;4:130-8
• Dyrby TB, Lundell H, Burke MW, Reislev NL, Paulson OB, Ptito M, Siebner HR. Interpolation of diffusion weighted imaging datasets. Neuroimage. 2014 Dec;103:202-13
• Ettrup A, da Cunha-Bang S, McMahon B, Lehel S, Dyssegaard A, Skibsted AW, Jørgensen LM, Hansen M, Baandrup AO, Bache S, Svarer C, Kristensen JL, Gillings N, Madsen J, Knudsen GM. Serotonin 2A receptor agonist binding in the human brain with [11C]Cimbi-36. J Cereb Blood Flow Metab. 2014 Jul;34(7):1188-96
• Feng L, Svarer C, Thomsen G, de Nijs R, Larsen VA, Jensen P, Adamsen D, Dyssegaard A, Fischer W, Meden P, Krieger D, Møller K, Knudsen GM, Pinborg LH. In Vivo Quantification of Cerebral Translocator Protein Binding in Humans Using 6-Chloro-2-(4'-123I-Iodophenyl)-3-(N,N-Diethyl)-Imidazo[1,2-a]Pyridine-3-Acetamide SPECT. J Nucl Med. 2014 Dec;55(12):1966-72
• Finnema SJ, Stepanov V, Ettrup A, Nakao R, Amini N, Svedberg M, Lehmann C, Hansen M, Knudsen GM, Halldin C. Characterization of [11C]Cimbi-36 as an Agonist PET Radioligand for the 5-HT2A and 5-HT2C Receptors in the Nonhuman Primate Brain. Neuroimage. 2014 Jan;84:342-53
• Fisher PM, Madsen MK, Mc Mahon B, Holst KK, Andersen SB, Laursen HR, Hasholt LF, Siebner HR, Knudsen GM. Three-week bright-light intervention has dose-related effects on threat-related corticolimbic reactivity and functional coupling. Biol Psychiatry. 2014 Aug 15;76(4):332-9
• Frokjaer VG, Erritzoe D, Holst KK, Madsen KS, Fisher PM, Madsen J, Svarer C, Knudsen GM. In abstinent MDMA users the cortisol awakening response is off-set but associated with prefrontal serotonin transporter binding as in non-users. Int J Neuropsychopharmacol. 2014 Aug;17(8):1119-28
• Greve DN, Svarer C, Fisher PM, Feng L, Hansen AE, Baare W, Rosen B, Fischl B, Knudsen GM. Cortical surface-based analysis reduces bias and variance in kinetic modeling of brain PET data. Neuroimage. 2014 May 15;92:225-3
• Hansen FH, Skjørringe T, Yasmeen S, Arends NV, Sahai MA, Erreger K, Andreassen TF, Holy M, Hamilton PJ, Neergheen V, Karlsborg M, Newman AH, Pope S, Heales SJ, Friberg L, Law I, Pinborg LH, Sitte HH, Loland C, Shi L, Weinstein H, Galli A, Hjermind LE, Møller LB, Gether U. Missense dopamine transporter mutations associate with adult parkinsonism and ADHD. J Clin Invest. 2014 Jul 1;124(7):3107-20
• Hansen HD, Herth MM, Ettrup A, Andersen VL, Lehel S, Dyssegaard A, Kristensen JL, Knudsen GM. Radiosynthesis and In Vivo Evaluation of Novel Radioligands for PET Imaging of Cerebral 5-HT7 Receptors. J Nucl Med. 2014 Apr;55(4):640-6
• Hansen HD, Lacivita E, Di Pilato P, Herth MM, Lehel S, Ettrup A, Andersen VL, Dyssegaard A, De Giorgio P, Perrone R, Berardi F, Colabufo NA, Mauro N, Knudsen GM, Leopoldo M. Synthesis, radiolabeling and in vivo evaluation of [11C](R)-1-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-3-(2-pyrazinyloxy)-2-propanol, a potential PET radioligand for the 5-HT7 receptor. Eur J Med Chem. 2014 May 22;79:152-63
• Herth MM, Leth-Petersen S, Lehel S, Hansen M, Knudsen GM, Gillings N, Madsen J, Kristensen JL. Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes. RSC Advances 4 (41), 21347-21350
• Hesse S, van de Giessen E, Zienteka F, Petroff D, Wintere K, Dickson JC, Tossici-Bolt L, Serah T, Asenbaum S, Darcourt J, Akdemir UO, Knudsen GM, Nobili F, Pagani M, Vanderborght T, Van Laere K,Varrone A,Tatsch K, Sabri O, Booij J. Association of central serotonin transporter availability and body mass index in healthy Europeans. Eur Neuropsychopharmacol. 2014 Aug;24(8):1240-7
• Haahr ME, Fisher PM, Jensen CG, Frokjaer VG, Mahon BM, Madsen K, Baaré WF, Lehel S, Norremolle A, Rabiner EA, Knudsen GM. Central 5-HT4 receptor binding as biomarker of serotonergic tonus in humans: a [11C]SB207145 PET study. Mol Psychiatry. 2014 Apr;19(4):427-32
• Jensen CG, Elsass P, Neustrup L, Bihal T, Flyger H, Kay SM, Khan S, Jensen SS, Pedersen A,Würtzen H. What to listen for in the first consultation. Breast cancer patients’ own focus on talking about acceptance-based psychological coping predicts decreased psychological distress and depression. Patient Educ Couns. 2014 Nov;97(2):165-72
• Jørgensen SR, Andersen MD, Overgaard A, Mikkelsen JD. Changes in RFamide-related peptide-1 (RFRP-1)-immunoreactivity during postnatal development and the estrous cycle. Endocrinology. 2014 Nov;155(11):4402-10
• Klein AB, Ultved L, Adamsen D, Santini MA, Tobeña A, Fernandez-Teruel A, Flores P, Moreno M, Cardona D, Knudsen GM, Aznar S, Mikkelsen JD. 5-HT2A and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains. Neuroscience. 2014 Mar 28;263:36-45
• Koch W, Unterrainer M, Xiong G, Bartenstein P, Diemling M, Varrone A, Dickson JC, Tossici-Bolt L, Sera T, Asenbaum S, Booij J, Kapucu OL, Kluge A, Ziebell M, Darcourt J, Nobili F, Pagani M, Hesse S, Vander Borght T, Van Laere K, Tatsch K, la Fougère C. Extrastriatal binding of [(123)I]FP-CIT in the thalamus and pons: gender and age dependencies assessed in a European multicentre database of healthy controls. Eur J Nucl Med Mol Imaging. 2014 Oct;41(10):1938-46
• Lacivita E, Niso M, Hansen HD, Di Pilato P, Herth MM, Lehel S, Ettrup A, Montenegro L, Perrone R, Berardi F, Colabufo NA, Leopoldo M, Knudsen GM. Design, synthesis, radiolabeling and in vivo evaluation of potential positron emission tomography (PET) radioligands for brain imaging of the 5-HT7 receptor. Bioorg Med Chem. 2014 Mar 1;22(5):1736-50
• Macoveanu J, Knorr U, Søndergaard MG, Jørgensen A, Fauerholdt-Jepsen M, Paulson OB, Knudsen GM, Siebner HR, Kessing LV. Altered reward processing in the orbitofrontal cortex and hippocampus in healthy first-degree relatives of patients with depression. Psychol Med. 2014 Apr;44(6):1183-95
• Macoveanu J, Fisher PM, Haahr ME, Frokjaer VG, Knudsen GM, Siebner HR. Effects of selective serotonin reuptake inhibition on neural activity related to risky decisions and monetary rewards in healthy males. Neuroimage. 2014 Oct;99:434-42
• Overgaard A, Ruiz-Pino F, Castellano JM, Tena-Sempere M and Mikkelsen JD. Disparate changes in kisspeptin and neurokinin B expression in the arcuate nucleus following sex steroid manipulation reveal differential regulation of the two KNDy peptides in rats. Endocrinology. 2014 Oct;155(10):3945-55
• Paulson OB, Hossmann KA, Ingvar M, Sokoloff L. In memoriam: Bo K Siesjö, 1930-2013. J Cereb Blood Flow Metab. 2014;34(1):1-1
• Pedersen SF, Ludvigsen TP, Johannesen HH, Löfgren J, Ripa RS, Hansen AE, Ettrup AJ, Christoffersen BØ, Pedersen HD, Olsen LH, Højgaard L, Kjær A. Feasibility of simultaneous PET/MR in diet-induced atherosclerotic minipig: a pilot study for translational imaging. Am J Nucl Med Mol Imaging. 2014 Aug 15;4(5):448-58
• Pyndt Jørgensen B, Hansen JT, Krych L, Larsen C, Klein AB, Nielsen DS, Josefsen K, Hansen AK, Sørensen DB. A Possible Link between Food and Mood: Dietary Impact on Gut Microbiota and Behavior in BALB/c Mice. PLoS One. 2014 Aug 18;9(8):e103398
• Rasmussen H, Ebdrup BH, Oranje B, Pinborg LH, Knudsen GM, Glenthøj B. Neocortical serotonin2A receptor binding predicts quetiapine associated weight gain in antipsychotic-naive first-episode schizophrenia patients. Int J Neuropsychopharmacol. 2014 Nov;17(11):1729-36
• Santini MA, Balu DT, Puhl MD, Hill-Smith TE, Berg AR, Lucki I, Mikkelsen JD, Coyle JT. D-serine deficiency attenuates the behavioral and cellular effects induced by the hallucinogenic 5-HT2A receptor agonist DOI. Behav Brain Res. 2014 Feb 1;259:242
• Sigurdsson ST, Paulson OB, Høj Nielsen A, Strandgaard S. Bradykinin antagonist counteracts the acute effect of both angiotensin-converting enzyme inhibition and of angiotensin receptor blockade on the lower limit of autoregulation of cerebral blood flow. J Cereb Blood Flow Metab. 2014 Mar;34(3):467-71
• Stenbæk DS, Jensen CG, Holst KK, Mortensen EL, Knudsen GM, Frokjaer VG. Does Harm Avoidance mediate effects of recollected parental bonding on mental distress in adulthood? Compr Psychiatry. 2014 May;55(4):1007-14
• Stenbæk DS, Hjordt LV, Haahr ME, Worm D, Hansen DL, Mortensen EL, Knudsen GM. Personality characteristics in surgery seeking and non-surgery seeking obese individuals compared to non-obese controls. Eating Behaviors. 2014 Aug 28;15(4):595-598
• Thomsen MS, Cinar B, Jensen MM, Lyukmanova EN, Shulepko MA, Tsetlin V, Klein AB, Mikkelsen, JD. Expression of the Ly-6 family proteins Lynx1 and Ly6H in the rat brain is compartmentalized, cell-type specific, and developmentally regulated. Brain Struct Funct. 2014 Nov;219(6):1923-34
• Visser AKD, Meerlo P, Ettrup A, Knudsen GM, Bosker FJ, den Boer JA, Dierckx RAJO, van Waarde A. Acute social defeat does not alter cerebral 5-HT2A receptor binding in male Wistar rats. Synapse 2014 Sep;68(9):379-86
• Wey HY, Catana C, Hooker JM, Dougherty DD, Knudsen GM, Wang DJ, Chonde DB, Rosen BR, Gollub RL, Kong J. Simultaneous fMRI-PET of the Opioidergic Pain System in Human Brain. Neuroimage. 2014 Nov 15;102 Pt 2:275-82
• Wu X, Hanson LG, Skimminge A, Sorensen PS, Paulson OB, Mathiesen HK, Blinkenberg M. Cortical N-acetyl aspartate is a predictor of long-term clinical disability in multiple sclerosis. Neurol Res. 2014 Aug;36(8):701-8

• Frøkjær VG. Molecular Imaging of Depressive Disorders. In: Dierckx R.A.J.O., Otte A., de Vries E.F.J., van Waarde A., den Boer J.A. (Eds.) PET and SPECT in Psychiatry (2014). Springer, New York (USA), ISBN: 9783642403835
• Knudsen GM, Hasselbalch SG. Imaging of the Serotonin System: Radiotracers and Applications in Memory Disorders. In: Dierckx, R.A.J.O., Otte, A., de Vries, E.F.J., van Waarde, A., Luiten, P.G.M. (Eds.) PET and SPECT of Neurobiological Systems (2014). Springer, New York (USA), ISBN: 9783642420139

2013

• Allen M, Smallwood J, Christensen J, Gramm D, Rasmussen B, Jensen CG, Roepstorff A, Lutz A. The balanced mind: the variability of task-unrelated thoughts predicts error monitoring. Front Hum Neurosci. 2013 Nov 7;7:743
• Andersen VL, Herth MM, Lehel S, Knudsen GM, Kristensen JL. Palladium-mediated conversion of para-aminoarylboronic esters into para-aminoaryl-11C-methanes. Tetrahedron Letters. 2013 Jan;54(3):213-6
• Beniczky S, Lantz G, Rosenzweig I, Åkeson P, Pedersen B, Pinborg LH, Ziebell M, Jespersen B, Fuglsang-Frederiksen A. Source localization of rhythmic ictal EEG activity: a study of diagnostic accuracy following STARD criteria. Epilepsia. 2013 Oct;54(10):1743-52
• Bortz DM, Mikkelsen JD, Bruno JP. Localized infusions of the partial alpha 7 nicotinic receptor agonist SSR180711 evoke rapid and transient increases in prefrontal glutamate release. Neuroscience. 2013 Dec 26;255:55-67
• Broberg BV, Madsen KH, Plath N, Olsen CK, Glenthøj BY, Paulson OB, Bjelke B, Søgaard LV. A schizophrenia rat model induced by early postnatal phencyclidine treatment and characterized by Magnetic Resonance Imaging. Behavioural Brain Research. 2013 Aug 1;250:1-8
• Christensen DZ, Thomsen MS, Mikkelsen JD. Reduced basal and novelty-induced levels of Activity-regulated cytoskeleton protein (Arc) mRNA in the cerebral cortex and hippocampus of APPswe/PS1dE9 transgenic mice. Neurochem Int. 2013 Jul;63(1):54-60
• Clemmensen C, Smajilovic S, Madsen AN, Klein AB, Holst B, Brauner-Osborne H. Increased susceptibility to diet-induced obesity in GPRC6A receptor knockout mice. J Endocrinol. 2013 Apr 15;217(2):151-60.
• da Cunha-Bang S, Stenbæk DS, Holst K, Licht CL, Jensen PS, Frokjaer VG, Mortensen EL, Knudsen GM. Trait aggression and trait impulsivity are not related to frontal cortex 5-HT2A receptor binding in healthy individuals. Psychiatry Res. 2013 May 30;212(2):125-31
• Dogonowski AM, Siebner HR, Sørensen PS, Wu X, Biswal B, Paulson OB, Dyrby TB, Skimminge A, Blinkenberg M, Madsen KH. Expanded functional coupling of subcortical nuclei with the motor resting-state network in multiple sclerosis. Mult Scler. 2013 Apr;19(5):559-66
• Dogonowski AM, Siebner HR, Soelberg Sørensen P, Paulson OB, Dyrby TB, Blinkenberg M, Madsen KH. Resting-state connectivity of pre-motor cortex reflects disability in multiple sclerosis. Acta Neurol Scand. 2013 Nov;128(5):328-35
• Elfving B, Christensen T, Ratner C, Wienecke J, Klein AB. Transient activation of mTOR following forced treadmill exercise in rats. Synapse. 2013 Sep;67(9):620-5
• Ettrup A, Holm S, Hansen M, Wasim M, Santini M, Palner M, Madsen J, Svarer C, Kristensen JL, and Knudsen GM. Preclinical safety assessment of the 5-HT2A receptor agonist PET radioligand [11C]Cimbi-36. Molecular Imaging and Biology. 2013 Aug;15(4):376-83
• Fagerlund B, Pinborg LH, Mortensen EL, Friberg L, Baaré WF, Gade A, Svarer C, Glenthøj BY. Relationship of frontal D2/3 binding potentials to cognition: a study of antipsychotic-naive schizophrenia patients. Int J Neuropsychopharmacol. 2013 Feb;16(1):23-36
• Fisher PM, Hariri AR. Identifying serotonergic mechanisms underlying the corticolimbic response to threat in humans. Philos Trans R Soc Lond B Biol Sci. 2013 Feb 25;368(1615):20120192
• Frokjaer VG, Erritzoe D, Jensen PS, Madsen J, Baaré W, Knudsen GM. Prefrontal serotonin transporter availability is positively associated with the cortisol awakening response. European Neuropsychopharmacology. 2013 Apr;23(4):285-94
• Grady CL, Siebner HR, Hornboll B, Macoveanu J, Paulson OB, Knudsen GM. Acute pharmacologically induced shifts in serotonin availability abolish emotion-selective responses to negative face emotions in distinct brain networks. Eur Neuropsychopharmacol. 2013 May;23(5):368-78
• Hansen HD, Ettrup A, Herth MM, Dyssegaard A, Ratner C, Gillings N, Knudsen GM. Direct comparison of [18F]MH.MZ and [18F]Altanserin for 5-HT2A molecular imaging with PET. Synapse. 2013 Jun;67(6):328-37
• Hansen HH, Jensen MM, Overgaard A, Weikop P, Mikkelsen JD. Tesofensine induces appetite suppression and weight loss with reversal of low forebrain dopamine levels in the diet-induced obese rat. Pharmacol Biochem Behav. 2013 Sep;110:265-71
• Hasselbalch BJ, Knorr U, Hasselbalch SG, Gade A, Kessing LV. The cumulative load of depressive illness is associated with cognitive function in the remitted state of unipolar depressive disorder. Eur Psychiatry. 2013 Aug;28(6):349-55
• Herth MM, Andersen VL, Lehel S, Madsen J, Knudsen GM, Kristensen JL. Development of a 11C-labeled tetrazine for rapid tetrazine-trans-cyclooctene ligation. Chem Commun (Camb). 2013 May 8;49(36):3805-7
• Holst KK, Budtz-Joergensen E. Linear Latent Variable Models: The lava-package. Computational Statistics. 2013;28(4):1385-1452
• Hornbøll B, Macoveanu J, Rowe J, Elliott R, Paulson OB, Siebner HR, Knudsen GM. Acute serotonin 2A receptor blocking alters the processing of fearful faces in the orbitofrontal cortex and amygdala. J Psychopharmacol. 2013 Oct;27(10):903-14
• Haagensen AM, Klein AB, Ettrup A, Matthews LR, Sørensen DB. Cognitive performance of göttingen minipigs is affected by diet in a spatial hole-board discrimination test. PLoS One. 2013 Nov 5;8(11):e79429
• Haahr ME, Fisher PM, Holst KK, Madsen K, Jensen CG, Marner L, Lehel S, Baaré W, Knudsen GM, Hasselbalch SG. The 5-HT4 receptor levels in hippocampus correlates inversely with memory test performance in humans. Human brain mapping. 2013 Nov;34(11):3066-74
• Janati A, Talbi R, Klosen P, Mikkelsen JD, Magoul R, Simonneaux V, El Ouezzani S. Distribution and seasonal variation in hypothalamic RF-amide peptides in a semi-desert rodent, the jerboa. J Neuroendocrinol. 2013 Apr;25(4):402-11
• Jørgensen CV, Jacobsen JP, Caron MG, Klein AB, Knudsen GM, Mikkelsen JD. Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice. Neurosci Lett. 2013 Oct 25;555:118-22
• Jørgensen CV, Klein AB, El-Sayed M, Knudsen GM, Mikkelsen JD. Metabotropic glutamate receptor 2 and corticotrophin-releasing factor receptor-1 gene expression is differently regulated by BDNF in rat primary cortical neurons. Synapse. 2013 Nov;67(11):794-800
• Kalbitzer J, Kalbitzer U, Knudsen GM, Cumming P, Heinz A. How the cerebral serotonin homeostasis predicts environmental changes: a model to explain seasonal changes of brain 5-HTT as intermediate phenotype of the 5-HTTLPR. Psychopharmacology (Berl). 2013 Dec;230(3):333-43
• Keller SH, Svarer C, Sibomana M. Attenuation correction for the HRRT PET-scanner using transmission scatter correction and total variation regularization. IEEE Trans Med Imaging. 2013 Sep;32(9):1611-21
• Klein AB, Jennum P, Knudsen S, Gammeltoft S, Mikkelsen JD. Increased serum brain-derived neurotrophic factor (BDNF) levels in patients with narcolepsy. Neuroscience Letters. 2013 Jun 7;544:31-5
• Knudsen SB, Strandgaard S, Paulson OB. Sekundær prævention af apopleksi med effektiv antihypertensiv behandling. Ugeskr Læger. 2013;175(15):1024
• Lie ME, Overgaard A, Mikkelsen JD. Effect of a postnatal high-fat diet exposure on puberty onset, estrous cycle regularity, and kisspeptin expression in female rats. Reprod Biol. 2013 Dec;13(4):298-308
• Lindquist SG, Duno M, Batbayli M, Puschmann A, Braendgaard H, Mardosiene S, Svenstrup K, Pinborg LH, Vestergaard K, Hjermind LE, Stokholm J, Andersen BB, Johannsen P, Nielsen JE. Corticobasal and ataxia syndromes widen the spectrum of C9ORF72 hexanucleotide expansion disease. Clin Genet. 2013 Mar;83(3):279-83
• Lou AR, Madsen KH, Julian HO, Toft PB, Kjaer TW, Paulson OB, Prause JU, Siebner HR. Postoperative increase in grey matter volume in visual cortex after unilateral cataract surgery. Acta Ophthalmol. 2013 Feb;91(1):58-65.
• Lund H, Krakauer M, Skimminge A, Sellebjerg F, Garde E, Siebner HR, Paulson OB, Hesse D, Hanson LG. Blood-brain barrier permeability of normal appearing white matter in relapsing-remitting multiple sclerosis. PLoS One. 2013;8(2):e56375
• Macoveanu J, Hornboll B, Elliott R, Erritzoe D, Paulson OB, Siebner H, Knudsen GM, Rowe JB. Serotonin 2A receptors, citalopram and tryptophan-depletion: a multimodal imaging study of their interactions during response inhibition. Neuropsychpharm. 2013 May;38(6):996-1005
• Macoveanu J, Rowe JB, Hornboll B, Elliott R, Paulson OB, Knudsen GM, Siebner HR. Serotonin 2A receptors contribute to the regulation of risk-averse decisions. Neuroimage. 2013 Dec;83:35-44
• Macoveanu J, Rowe JB, Hornboll B, Elliott R, Paulson OB, Knudsen GM, Siebner HR. Playing it safe but losing anyway-Serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion. Eur Neuropsychopharmacol. 2013 Aug;23(8):919-30
• Melchior L, Bertelsen B, Debes NM, Groth C, Skov L, Mikkelsen JD, Brøndum-Nielsen K, Tümer Z. Microduplication of 15q13.3 and Xq21.31 in a family with tourette syndrome and comorbidities. Am J Med Genet B Neuropsychiatr Genet. 2013 Dec;162(8):825-31
• Menezes MM, Santini MA, Benvenga MJ, Marek GJ, Merchant KM, Mikkelsen JD, Svensson KA. The mGlu2/3 Receptor Agonists LY354740 and LY379268 Differentially Regulate Restraint-Stress-Induced Expression of c-Fos in Rat Cerebral Cortex. Neuroscience Journal, vol. 2013, Article ID 736439, 8 pages, 2013. https://doi.org/10.1155/2013/736439
• Mohammadi D. INMiND: getting to the bottom of neuroinflammation. Lancet Neurol. 2013 Dec;12(12):1135-6
• Nobili F, Naseri M, De Carli F, Asenbaum S, Booij J, Darcourt J, Ell P, Kapucu O, Kemp P, Svarer C, Morbelli S, Pagani M, Sabri O, Tatsch K, Tossici-Bolt L, Sera T, Borght TV, Van Laere K, Varrone A. Automatic semi-quantification of [123I] FP-CIT SPECT scans in healthy volunteers using BASGAN – version 2. Results from the ENC-DAT database. European Journal of Nuclear Medicine and Molecular Imaging. 2013 Apr;40(4):565-73
• Overgaard A, Holst KK, Mandrup K, Boberg J, Christiansen S, Jacobsen PR, Hass U, Mikkelsen JD. The effect of perinatal exposure to ethinyl oestradiol or a mixture of endocrine disrupting pesticides on kisspeptin neurons in the rat hypothalamus. NeuroToxicology. 2013 Jul;37:154-62
• Overgaard A, Tena-Sempere M, Franceschini I, Desroziers E, Simonneaux V, Mikkelsen JD. Comparative Analysis of Kisspeptin-immunoreactivity Reveals Genuine Differences between Rats and Mice. Peptides. 2013 Jul;45:85-90
• Paterson LM, Kornum B, Nutt D, Pike V, Knudsen GM. 5-HT radioligands for human brain imaging with PET and SPECT. Med Res Rev. 2013 Jan;33(1):54-111
• Piekarski DJ, Zhao S, Jennings KJ, Iwasa T, Legan SJ, Mikkelsen JD, Tsutsui K, Kriegsfeld LJ. Gonadotropin-inhibitory hormone reduces sexual motivation but not lordosis behavior in female Syrian hamsters (Mesocricetus auratus). Horm Behav. 2013 Aug;64(3):501-10
• Rasmussen H, Ebdrup BH, Aggernaes B, Lublin H, Oranje B, Pinborg LH, Knudsen GM, Glenthøj B. Norquetiapine and Depressive Symptoms in Initially Antipsychotic-Naive First-Episode Schizophrenia. J Clin Psychopharmacol. 2013 Apr;33(2):266-269
• Reverte I, Klein AB, Domingo JL, Colomina MT. Long term effects of murine postnatal exposure to decabromodiphenyl ether (BDE-209) on learning and memory are dependent upon APOE polymorphism and age. Neurotoxicol Teratol. 2013 Nov-Dec;40:17-27
• Risgaard R, Ettrup A, Balle T, Dyssegaard A, Hansen HD, Lehel S, Madsen J, Pedersen H, Püschl A, Badolo L, Bang-Andersen B, Knudsen GM, Kristensen JL. Radiolabelling and PET brain imaging of the α1-adrenoceptor antagonist Lu AE43936. Nuclear Medicine and Biology. 2013 Jan;40(1):135-40
• Sander CY, Hooker JM, Catana C, Normandin MD, Alpert NM, Knudsen GM, Vanduffel W, Rosen BR, Mandeville JB. Neurovascular coupling to D2/D3 receptor occupancy using simultaneous PET/functional MRI. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11169-74
• Santini MA, Ratner C, Aznar S, Klein AB, Knudsen GM, Mikkelsen JD. Enhanced prefrontal serotonin 2A receptor signaling in the subchronic PCP mouse model of schizophrenia. Journal of Neuroscience Research. 2013 May;91(5):634-41
• Söderlund AT, Dickson JC, Prvulovich E, Ben-Haim S, Kemp P, Booij J, Nobili F, Thomsen G, Sabri O, Koulibaly PM, Akdemir UO, Pagani M, van Laere K, Dobrozemsky G, George J, Sera T, Tatsch K, Bomanji J. Value of semiquantitative analysis for clinical reporting of 123I-2-β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl)nortropane SPECT studies. Journal of Nuclear Medicine. 2013 May;54(5):714-22
• Thomsen G, Knudsen GM, Jensen PS, Ziebell M, Holst KK, Asenbaum S, Booij J, Darcourt J, Dickson JC, Kapucu ÖL, Nobili F, Sabri O, Sera T, Tatsch K, Tossici-Bolt L, van Laere K, Vanderborght T, Varrone A, Pagani M, Pinborg LH. No difference in striatal dopamine transporter availability between active smokers, ex-smokers and non-smokers using [123I]FP-CIT (DaTSCAN) and SPECT. EJNMMI Res. 2013 May 20;3(1):39
• Thomsen G, Ziebell M, Jensen PS, da Cuhna-Bang S, Knudsen GM, Pinborg LH. No correlation between body mass index and striatal dopamine transporter availability in healthy volunteers using SPECT and [123I]PE2I. Obesity (Silver Spring). 2013 Sep;21(9):1803-6
• van de Giessen E, Hesse S, Caan MW, Zientek F, Dickson JC, Tossici-Bolt L, Sera T, Asenbaum S, Guignard R, Akdemir UO, Knudsen GM, Nobili F, Pagani M, Vander Borght T, Van Laere K, Varrone A, Tatsch K, Booij J, Sabri O. No association between striatal dopamine transporter binding and body mass index: A multi-center European study in healthy volunteers. Neuroimage. 2013 Jan 1;64:61-7
• Varrone A, Dickson JC, Tossici-Bolt L, Sera T, Asenbaum S, Booik J, Kapucu OL, Kluge A, Knudsen GM, Koulibaly PM, Nobili F, Pagani M, Sabri O, Vander Borght T, Van Laere K, Tatsch K. European multicentre database of healthy controls for [¹²³I]FP-CIT SPECT (ENC-DAT): age-related effects, gender differences and evaluation of different methods of analysis. Eur J Nucl Med Mol Imaging. 2013 Jan;40(2):213-27
• Ziebell M, Andersen BB, Pinborg LH, Knudsen GM, Stockholm J, Thomsen G, Karlsborg M, Høgh P, Mørk ML, Hasselbalch SG. Striatal dopamine transporter binding does not correlate with clinical severity in dementia with Lewy bodies. J Nucl Med. 2013 Jul;54(7):1072-6

• Paulson OB, Henriksen HH, Parving H-H. Professor, Overlæge, dr.med. Niels A. Lassen – Klinisk fysiolog og hjerneforsker. I: Hansen SH, Permin H, eds. Bispebjerg Hospital 100 år. Mosaikker af et hospitals liv. Eget Forlag 2013:216-21
• Thage O, Paulson OB. Etablering og tidlig udvikling1913-1975. I: Paulson OB, Thage O, Waldemar G, eds. Neurologi i 100 år. Eget Forlag. 2013:10-19
• Paulson OB, Sørensen PS. Udviklingen fortsætter.1975 til 1999. I: Paulson OB, Thage O, Waldemar G, eds. Neurologi i 100 år. Eget Forlag. 2013:28-41
• Paulson OB, Sørensen PS. Neuroonkologi. I: Paulson OB, Thage O, Waldemar G, eds. Neurologi i 100 år. Eget Forlag. 2013:112-115
• Paulson OB, Knudsen GM. Billeddannelse af hjernen. I: Paulson OB, Thage O, Waldemar G, eds. Neurologi i 100 år. Eget Forlag. 2013:128-133
• Knudsen GM, Mikkelsen JD, Paulson OB, Svarer C. Klinisk neurobiologi. I: Paulson OB, Thage O, Waldemar G, eds. Neurologi i 100 år. Eget Forlag. 2013:134-143
• Paulson OB. Professorer og overlæger 1913-2013. I: Paulson OB, Thage O, Waldemar G, eds. Neurologi i 100 år. Eget Forlag. 2013:162-166
• Paulson OB. Publikationer 1972-2013. I: Paulson OB, Thage O, Waldemar G, eds. Neurologi i 100 år. Eget Forlag. 2013:168-172
  

• Absalom N, Eghorn LF, Villumsen IS, Karim N, Bay T, Olsen JV, Knudsen GM, Bräuner-Osborne H, Frølund B, Clausen RP, Chebib M, Wellendorph P. α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB). Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13404-9
• Ancel C, Bentsen AH, Sébert ME, Tena-Sempere M, Mikkelsen JD, Simonneaux V.Stimulatory Effect of RFRP-3 on the Gonadotrophic Axis in the Male Syrian Hamster: The Exception Proves the Rule. Endocrinology. 2012 Mar;153(3):1352-63
• Balslev D, Siebner HR, Paulson OB, Kassuba T. The cortical eye proprioceptive signal modulates neural activity in higher-order visual cortex as predicted by the variation in visual sensitivity. Neuroimage. 2012 Jul 16;61(4):950-6
• Blinkenberg M, Akeson P, Sillesen H, Lövgaard S, Sellebjerg F, Paulson OB, Siebner HR, Sørensen PS. Chronic cerebrospinal venous insufficiency and venous stenoses in multiple sclerosis. Acta Neurol Scand. 2012 Dec;126(6):421-7
• Blinkenberg M, Mathiesen HK, Tscherning T, Jønsson A, Svarer C, Holm S, Sellebjerg F, Paulson OB, Hanson LG, Sorensen PS. Cerebral metabolism, magnetic resonance spectroscopy and cognitive dysfunction in early multiple sclerosis: an exploratory study. Neurol Res. 2012 Jan;34(1):52-8
• Clemmensen C, Aznar S, Knudsen GM and Klein AB. The microtubule-associated protein 1A (MAP1A) is an early molecular target of soluble Aβ-peptide Cellular and Molecular. Cell Mol Neurobiol. 2012 May;32(4):561-6
• Dickson JC, Tossici-Bolt L, Sera T, de Nijs R, Booij J, Bagnara MC, Seese A, Koulibaly PM, Akdemir UO, Jonsson C, Koole M, Raith M, Lonsdale MN, George J, Zito F, Tatsch K. Proposal for the standardisation of multi-centre trials in nuclear medicine imaging: prerequisites for a European 123I-FP-CIT SPECT database. Eur J Nucl Med Mol Imaging. 2012 Jan;39(1):188-97
• Eiberg H, Hansen L, Korbo L, Nielsen I, Svenstrup K, Bech S, Pinborg L, Friberg L, Hjermind L, Olsen O, Nielsen J. Novel mutation in ATP13A2 widens the spectrum of Kufor-Rakeb syndrome (PARK9).Clin Genet. 2012 Sep;82(3):256-63
• Fisher PM, Holst KK, Mc Mahon B, Haahr ME, Madsen K, Gillings N,  Baaré WF, Jensen PS,  Knudsen GM. 5-HTTLPR status predictive of neocortical 5-HT4 binding assessed with [11C]SB207145 PET in humans. Neuroimage. 2012 Aug 1;62(1):130-6
• Fisher PM, Hariri AR. Linking variability in brain chemistry and circuit function through multimodal human neuroimaging. Genes Brain Behav. 2012 Aug;11(6):633-42
• Gagnon L, Schneider FC, Siebner HR, Paulson OB, Kupers R, Ptito M. Activation of the hippocampal complex during tactile maze solving in congenitally blind subjects. Neuropsychologia. 2012;50:1663-71.
• Hasselbalch BJ, Knorr U, Bennike B, Hasselbalch SG, Søndergaard MH, Kessing LV. Decreased levels of brain-derived neurotrophic factor in the remitted state of unipolar depressive disorder. Acta Psychiatr Scand. 2012 Sep;126(3):157-64
• Herth MM, Kramer V, Gillings N, Rösch F, Knudsen GM. Direct radiofluorination of [18F]MH.MZ for 5-HT2A receptor molecular imaging with PET. Journal of Labelled Compounds and Radiopharmaceuticals 2012; 55(9):354-358
• Herth MM, Hansen HD, Ettrup A, Dyssegaard A, Lehel S, Kristensen J, Knudsen GM. Synthesis and evaluation of [11C]Cimbi-806 as a potential PET ligand for 5-HT7 receptor imaging. Bioorganic & Medicinal Chemistry. 2012 July;20(14):4574-81
• Herth MM, Volk B, Pallagi K, Bech LK, Antoni FA, Knudsen GM, Kristensen JL. Synthesis and in vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT7 Receptor Imaging with PET. ACS Chemical Neuroscience. 2012 Dec 19;3(12):1002-7
• Haahr ME, Rasmussen PM, Madsen K, Marner L, Ratner C, Gillings N, Barré WF, Knudsen GM. Obesity is associated with high serotonin 4 receptor availability in the brain reward circuitry. Neuroimage. 2012 Jul 16;61(4):884-8
• Jacobsen J, Hansen HH, Kiss A, Mikkelsen JD. The α4β2 nicotine acetylcholine selective agonist ispronicline induces c-Fos expression in selective regions of the rat forebrain. Neurosci Lett. 2012 25;515(1):7-11
• Jennings KA, Licht CL, Bruce A, Lesch KP, Knudsen GM, Sharp T. Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HT4 receptor levels. Int J Neuropsychopharmacol. 2012 Sep;15(8):1099-107
• Jensen CG, Vangkilde S, Frokjaer V, Hasselbalch SG. Mindfulness training affects attention-or is it attentional effort? J Exp Psychol Gen. 2012, 141(1):106–123
• Jensen CG, Parker A. Entangled in the womb? A pilot study on the possible physiological connectedness between identical twins with different embryonic backgrounds. Explore (NY). 2012 Nov;8(6):339-47
• Keller SH, Sibomana M, Olesen OV, Svarer C, Holm S, Andersen FL, Højgaard L. Methods for Motion Correction Evaluation Using 18F-FDG Human Brain Scans on a High-Resolution PET Scanner. J Nucl Med. 2012 Mar;53(3):495-504
• Koefoed P, Wolbye DPD, Hansen TVO, Eplov LF, Christiansen SH, Mors O, Kessing LV, Werge T,Kaipio K, Pesonen U, Fahmy T, Mellerup E, Jakobsen KD, Hansen ES, Knudsen GM, Bukh JD, Bock C, Lindberg C, Kristensen AS, Dam H, Nordentoft M,  Als TD, Wang AG, Gether U, Rehfeld JF, Bolwig TG. Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression. Acta Neuropsychiatrica. 2012 April;24(2):81-90
• Lagerburg V, de Nijs R, Holm S, Svarer C. A comparison of different energy window subtraction methods to correct for scatter and downscatter in I-123 SPECT imaging. Nucl Med Commun. 2012 Jul;33(7):708-18
• Licht CL, Christoffersen M, Okholm M, Damgaard L, Fink-Jensen A, Knudsen GM, Erritzoe D. Simultaneous polysubstance use among Danish 3,4-methylenedioxymethamphetamine and hallucinogen users: combination patterns and proposed biological bases. Hum Psychopharmacol. 2012 Jul;27(4):352-63
• Lund H, Jønsson A, Andresen J, Rostrup E, Paulson OB, Sørensen PS. Cognitive deficits in multiple sclerosis: correlations with T2 changes in normal appearing brain tissue. Acta Neurol Scand. 2012 May;125(5):338-44
• Madsen K, Hasselbalch BJ, Frederiksen KS, Haahr ME, Gade A, Law I, Price JC, Knudsen GM, Kessing LV, Hasselbalch SG. Lack of association between prior depressive episodes and cerebral [11C]PiB binding. Neurobiol Aging. 2012 Oct;33(10):2334-42
• Madsen KS, Jernigan TL, Iversen P, Frokjaer VG, Mortensen EL, Knudsen GM, Baaré WF. Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture. Psychiatry Res. 2012 Jan 30;201(1):63-72
• Madsen KS, Jernigan TL, Iversen P, Frokjaer VG, Knudsen GM, Siebner HR, Baaré WF. Hypothalamic-pituitary-adrenal axis tonus is associated with hippocampal microstructural asymmetry. Neuroimage. 2012 Oct 15;63(1):95-103
• Marner L, Frøkjær VG, Kalbitzer J, Lehel S, Madsen K, Baaré WF, Knudsen GM, Hasselbalch SG. Loss of serotonin 2A receptors exceeds loss of serotonergic projections in early Alzheimer's disease. A combined [11C]DASB and [18F]altanserin-PET study. Neurobiol Aging. 2012 Mar;33(3):479-87
• Marner L. Communication among neurons. Dan Med J. 2012 Apr;59(4):B4427
• Mikkelsen JD, Jacobsen J, Kiss A. Differential sensitivity to nicotine among hypothalamic magnocellular neurons. Endocr Regul. 2012 Jan;46(1):13-20
• Mikkelsen JD, Rasmussen MA, Meyer M, Knudsen GM. Reprogrammering af modne celler til neuroner. Ugeskr Laeger. 2012 Mar 19;174(12):786
• Paulson OB, Kanno I, Reivich M, Sokoloff L. History of International Society for Cerebral Blood Flow and Metabolism. J Cereb Blood Flow Metab. 2012 Jul;32(7):1099-106
• Paulson O, Bolwig, T. Det værste halsonde – patientens oplevelse, når det går godt og kunne være gået gruelig galt. Kronik. Ugeskr Laeger 2012;174:1628-1629
• Pinborg LH, Feng L, Haahr ME, Gillings N, Dyssegaard A, Madsen J, Svarer C, Yndgaard S, Kjaer TW, Parsey RV, Hansen HD, Ettrup A, Paulson OB, Knudsen GM. No change in [11C]CUMI-101 binding to 5-HT1A receptors after intravenous citalopram in human. Synapse 2012 Oct;66(10):880-4
• Ptito M, Matteau I, Wang AZ, Paulson OB, Siebner HR, Kupers R. Crossmodal Recruitment of the Ventral Visual Stream in Congenital Blindness. Neural Plasticity 2012;2012:304045
• Ramsøy TZ, Liptrot MG, Skimminge A, Lund TE, Sidaros K, Christensen MS, Baaré W, Paulson OB, Jernigan TL, Siebner HR. Healthy aging attenuates task-related specialization in the human medial temporal lobe. Neurobiol Aging. 2012 Sep;33(9):1874-89 
• Ratner C, Ettrup A, Bueter M, Haahr ME, Compan V, le Roux C, Levin B, Hansen H, Knudsen GM. Cerebral markers of the serotonergic system in rat models of obesity and after Roux-en-Ygastric bypass. Obesity. 2012 Oct;20(10):2133-41
• Reverte I, Klein AB, Ratner C, Domingo JL, Columina MT. Behavioral phenotype and BDNF differences related to ApoE isoforms and sex in young transgenic mice. Exp Neurol. 2012 Sep;237(1):116-25
• Thomsen MS, Mikkelsen JD. The α7 nicotinic acetylcholine receptor complex: one, two or multiple drug targets? Curr Drug Targets. 2012 May;13(5):707-20
• Thomsen MS, Mikkelsen JD. Type I and II positive allosteric modulators (PAMs) differentially modulate agonist-induced upregulation of alpha7 nicotinic acetylcholine receptors (nAChRs). J Neurochem. 2012 Oct;123(1):73-83
• Thomsen MS, Mikkelsen JD. The alpha7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-alpha release from microglia. J Neuroimmunol. 2012 Oct 15;251(1-2):65-72
• Ziebell M, Khalid U, Klein AB, Aznar S, Thomsen G, Jensen P, Knudsen GM. Striatal dopamine transporter binding correlates with serum BDNF levels in patients with striatal dopaminergic neurodegeneration. Neurobiol Aging. 2012 Feb;33(2):428
• Ziebell M, Andersen BB, Thomsen G, Pinborg LH, Karlsborg M, Hasselbalch SG, Knudsen GM. Predictive value of dopamine transporter SPECT imaging with [123I]PE2I in patients with subtle parkinsonian symptoms. European Journal of Nuclear Medicine and Molecular Imaging. 2012 Feb;39(2):242-50

• Knudsen GM. Blood-brain barrier transport of lactate. In: Neural metabolism in vivo (eds. Choi I-Y, Gruetter R) Advances in Neurobiology (ed Lajtha A), vol. 4. 2012. Springer
  

• Ansel L, Bentsen AH, Ancel C, Bolborea M, Klosen P, Mikkelsen JD, Simonneaux V. Peripheral kisspeptin reverses short photoperiod-induced gonadal regression in Syrian hamsters by promoting GNRH release. Reproduction. 2011;142(3):417-25
• Aznar S, Knudsen GM. Depression and Alzheimer's Disease: Is stress the initiating factor in a common neuropathological cascade? J Alzheimers Dis. 2011;23(2):177-93
• Castellano JM, Bentsen AH, Sánchez-Garrido MA, Ruiz-Pino F, Romero M, Garcia-Galiano D, Aguilar E, Pinilla L, Diéguez C, Mikkelsen JD, Tena-Sempere M. Early metabolic programming of puberty onset: impact of changes in postnatal feeding and rearing conditions on the timing of puberty and development of the hypothalamic kisspeptin system. Endocrinology. 2011;152(9):3396-408
• Damsted SK, Born AP, Paulson OB, Uldall P. Exogenous glucocorticoids and adverse cerebral effects in children. Eur J Paediatr Neurol. 2011;15(6):465-77
• El-Sayed M, Hofman-Bang J, Mikkelsen JD. Effect of brain derived neurotrophic factor on activity regulated cytoskeleton associated protein gene expression in primary frontal cortical neurons. Comparison with NMDA and AMPA. Eur J Pharmacol. 2011; 25;660(2-3):351-7
• Erritzoe D, Frokjaer VG, Holst KK, Christoffersen M, Johansen SS, Svarer C, Madsen J, Rasmussen PM, Ramsøy T, Jernigan TL, Knudsen GM. In Vivo Imaging of Cerebral Serotonin Transporter and Serotonin2A Receptor Binding in 3,4-Methylenedioxymethamphetamine (MDMA or "Ecstasy") and Hallucinogen Users. Arch Gen Psychiatry. 2011;68(6):562-76
• Ettrup A, Kornum B, Weikop P, Knudsen GM. An approach for serotonin depletion in pigs: Effects on serotonin receptor binding. Synapse 2011;65(2):136-45
• Ettrup A, Hansen M, Santini MA, Paine J, Gillings N, Palner M, Lehel S, Herth MM, Madsen J, Kristensen J, Begtrup M, Knudsen GM. Radiosynthesis and in vivo evaluation of a series of substituted (11)C-phenethylamines as 5-HT (2A) agonist PET tracers. Eur J Nucl Med Mol Imaging. 2011;38(4):681-93
• Ettrup A, Mikkelsen JD, Lehel S, Madsen J, Nielsen EO, Timmermann DB, Peters D and KnudsenGM; [11C]NS14492 as a novel PET radioligand for imaging cerebral α7 nicotinic acetylcholine receptors: in vivo evaluation and drug occupancy measurements. J Nucl Med. 2011;52(9):1449-56
• Jennings KA, Licht CL, Bruce A, Lesch KP, Knudsen GM, Sharp T. Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HT4 receptor levels. The International Journal of Neuropsychopharmacology 2011;16:1-9
• Jensen MM, Lange SC, Thomsen MS, Hansen HH, Mikkelsen JD. The Pharmacological Effect of KCNQ (Kv7) Positive Modulators on Dopamine Release from Striatal Slices. Basic Clin Pharmacol Toxicol. 2011:339-42
• Jensen PS, Thomsen G, Ziebell M, deNijs, R, Svarer C, Malik U, Skouboe G, Knudsen GM. Validation of a Method for Accurate and Highly Reproducible Quantification of Brain Dopamine Transporter SPECT Studies. J. Nuclear Medicine and Technology2011;39(4):271-8
• Klein AB, Williamson R, Santini MA, Clemmensen C, Ettrup A, Rios M, Knudsen GM, Aznar S. Blood BDNF concentrations reflect brain tissue BDNF levels across species. Int J Neuropsychopharmacol. (2011), 14, 347–353
• Kornum BR, Knudsen GM. Cognitive testing of pigs (Sus scrofa) in translational biobehavioral research. Neurosci Biobehav Rev 2011;35(3):437-51
• Kupers R, Frokjaer V, Erritzoe D, Naert A, Budtz-Joergensen E, Nielsen FA, Kehlet H, Knudsen GM. Serotonin transporter binding in the hypothalamus correlates negatively with tonic heat pain ratings in healthy subjects: a [11C]DASB PET study. Neuroimage 2011;54(2):1336-43
• Kupers R, Beaulieu-Lefebvre M, Schneider FC, Kassuba T, Paulson OB, Siebner HR, Ptito M. Neural correlates of olfactory processing in congenital blindness. Neuropsychologia 2011;49(7):2037-44
• Liu X, Cannon DM, Akula N, Moya PR, Knudsen GM, Arentzen TE, Steele J, Laje G, Drevets WC, McMahon FJ. A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study. Molecular Psychiatry 2011; 16, 584–5
• Lou AR, Madsen KH, Paulson OB, Julian HO, Prause JU, Siebner HR, Kjaer TW. Monocular Visual Deprivation Suppresses Excitability in Adult Human Visual Cortex. Cereb Cortex. 2011:2876-82
• Madsen J, Elfving B, Frøkjær VG, Kornum BR, Thomsen G, Martiny L, Knudsen GM. Synthesis and Biological Evaluation of 125I/123I-Labelled Analogues of Citalopram and Escitalopram as Potential Radioligands for Imaging of the Serotonin Transporter. J. Label Compd. Radiopharm 2011, 54 185–190
• Madsen K, Haahr M, Marner L, Keller SH, Baaré W, Svarer C, Hasselbalch SG, Knudsen GM. Age and Sex Effects on 5-HT(4) Receptors in the Human Brain – A [11C]SB207145 PET Study. Journal of Cerebral Blood Flow & Metabolism 2011;31(6):1475-81
• Madsen K, Erritzoe D, Mortensen EL, Gade A, Madsen J, Baaré W, Knudsen GM, Hasselbalch SG. Cognitive Function is Related to Fronto-striatal Serotonin Transporter Levels - A Brain PET Study in Young Healthy Subjects. Psychopharmacology (Berl). 2011;213(2-3):573-81
• Madsen K, Neumann WJ, Holst K, Marner L, Haarh MT, Lehel S, Knudsen GM, Hasselbalch SG. Cerebral Serotonin 4 receptors and Amyloid-β in Early Alzheimer’s Disease. J Alzheimers Dis. 2011; 1;26(3):457-66
• Madsen K, Marner L, Haahr M, Gillings N, Knudsen GM. Mass Dose Effects and In Vivo Affinity in Brain PET Receptor Studies – A Study of Cerebral 5-HT4 Receptor Binding with [11C]SB207145. Nuclear medicine and biology 2011;38(8):1085-91
• Marner L, Knudsen GM, Madsen K, Holm S, Baaré W, Hasselbalch SG. The reduction of Baseline Serotonin 2A Receptors in Mild Cognitive Impairment is stable at Two-year Follow-up. J Alzheimers Dis. 2011;23(3):453-9
• Palner M, Underwood MD, Kumar DJ, Arango V, Knudsen GM, Mann JJ, Parsey RV. Ex vivo evaluation of the serotonin 1A receptor partial agonist [(3)H]CUMI-101 in awake rats. Synapse. 2011;65(8):715-23
• Palner M, Kjaerby C, Knudsen GM, Cummings P. Effects of unilateral 6-OHDA lesion on [3H]NPA binding in striatum ex vivo, and vulnerability to amphetamine-evoked dopamine release in rat. Neurochemistry International 58 (2011) 243–247
• Rasmussen H, Ebdrup BH, Erritzoe D, Aggernaes B, Oranje B, Kalbitzer J, Pinborg LH, Baaré WF, Svarer C, Lublin H, Knudsen GM, Glenthoj B. Serotonin2A receptor blockade and clinical effect in first-episode schizophrenia patients treated with quetiapine. Psychopharmacology (Berl). 2011;213(2-3):583-92
• Ryberg C, Rostrup E, Paulson OB, Barkhof F, Scheltens P, van Straaten EC, van der Flier WM, Fazekas F, Schmidt R, Ferro JM, Baezner H, Erkinjuntti T, Jokinen H, Wahlund LO, Poggesi A, Pantoni L, Inzitari D, Waldemar G. Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: A 3-year follow-up of the LADIS study cohort. J Neurol Sci. 2011 Aug 15;307(1-2):100-105
• Salem LC, Hejl AM, Garde E, Leffers AM, Paulson OB, Waldemar G. White matter hyperintensities and prepulse inhibition in a mixed elderly population. Psychiatry Res. 2011 30;194(3):314-8
• Santini MA, Klein AB, El-Sayed M, Ratner C, Knudsen GM, Mikkelsen JD, Aznar S. Novelty-induced activity-regulated cytoskeletal-associated protein (arc) expression in frontal cortex requires Serotonin 2A receptor activation. Neuroscience 2011, 8;190:251-7
• Söderman A, Mikkelsen JD, West MJ, Christensen DZ, Jensen MS. Activation of nicotinic α(7) acetylcholine receptor enhances long term potentation in wild type mice but not in APPswe/PS1ΔE9 mice. Neurosci Lett 2011;487(3):325-9
• Thomsen MS, Weyn A, Mikkelsen JD. Hippocampal α7 Nicotinic Acetylcholine Receptor Levels in Patients with Schizophrenia, Bipolar  Disorder, or Major Depressive Disorder. Bipolar Disorders 2011;13(7-8):701-7
• Thomsen MS, El-Sayed M, Mikkelsen JD. Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats.PLoS One. 2011; 6(11) :e27014
• Vestergaard M, Madsen KS, Baaré WF, Skimminge A, Ejersbo LR, Ramsøy TZ, Gerlach C, Akeson P, Paulson OB, Jernigan TL. White Matter Microstructure in Superior Longitudinal Fasciculus Associated with Spatial Working Memory Performance in Children. J Cogn Neurosci. 2011;23(9):2135-46
• Williams WP 3rd, Jarjisian SG, Mikkelsen JD, Kriegsfeld LJ. Circadian control of kisspeptin and a gated GnRH response mediate the preovulatory luteinizing hormone surge. Endocrinology. 2011 Feb;152(2):595-606
  

• Ansel L, Bolborea M, Bentsen AH, Klosen P, Mikkelsen JD, Simonneaux V. Differential regulation of kiss1 expression by melatonin and gonadal hormones in male and female Syrian hamsters. J Biol Rhythms. 2010;25(2):81-91
• Axel AM, Mikkelsen JD, Hansen HH. Tesofensine, a Novel Triple Monoamine Reuptake Inhibitor, Induces Appetite Suppression by Indirect Stimulation of alpha(1) Adrenoceptor and Dopamine D(1) Receptor Pathways in the Diet-Induced Obese Rat. Neuropsychopharmacology 2010;35(7):1464-76
• Aznar S, Klein AB, Santini MA, Knudsen GM, Henn F, Gass P, Vollmayr B. Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness. Synapse 2010;64(7):561-5
• Baaré WF, Vinberg M, Knudsen GM, Paulson OB, Langkilde AR, Jernigan TL, Kessing LV. Hippocampal volume changes in healthy subjects at risk of unipolar depression. J Psychiatr Res 2010;44(10):655-62
• Bentsen AH, Ansel L, Simonneaux V, Tena-Sempere M, Juul A, Mikkelsen JD. Maturation of kisspeptinergic neurons coincides with puberty onset in male rats. Peptides 2010;31(2):275-83
• Benveniste H, Fowler JS, Rooney WD, Scharf BA, Backus WW, Izrailtyan I, Knudsen GM, Hasselbalch SG, Volkow ND. Cocaine is Pharmacologically Active in the Non-Human Primate Fetal brain. Proc Natl Acad Sci U S A 2010;107(4):1582-7
• Bundzikova J, Pirnik Z, Zelena D, Mikkelsen JD, Kiss A. The alpha(2)-adrenoceptors do not modify the activity of tyrosine hydroxylase, corticoliberine, and neuropeptide Y producing hypothalamic magnocellular neurons ion the Long Evans and Brattleboro rats. J Physiol Pharmacol 2010;61(4):391-8
• Castellano JM, Bentsen AH, Romero M, Pineda R, Ruiz-Pino F, Garcia-Galiano D, Sanchez-Garrido MA, Pinilla L, Mikkelsen JD, Tena-Sempere M. Acute inflammation reduces kisspeptin immunoreactivity at the arcuate nucleus and decreases responsiveness to kisspeptin independently of its anorectic effects. Am J Physiol Endocrinol Metab 2010;299(1):E54-61
• Castellano JM, Bentsen AH, Mikkelsen JD, Tena-Sempere M. Kisspeptins: Bridging energy homeostasis and reproduction. Brain Res 2010;1364:129-38
• Christensen DZ, Mikkelsen JD, Hansen HH, Thomsen MS. Repeated administration of α7 nicotinic acetylcholine receptor (nAChR) agonists, but not positive allosteric modulators, increases α7 nAChR levels in the brain. J Neurochem 2010;114(4):1205-16
• de Nijs R, Holm S, Thomsen G, Ziebell M, Svarer C. Experimental determination of the weighting factor for the energy window subtraction-based downscatter correction for I-123 in brain SPECT studies. J Med Phys 2010;35(4):215-22
• Desroziers E, Mikkelsen J, Simonneaux V, Keller M, Tillet Y, Caraty A, Franceschini I. Mapping of kisspeptin fibres in the brain of the pro-oestrous rat. J Neuroendocrinol. 2010 Oct;22(10):1101-12
• Ebdrup BH, Glenthøj B, Rasmussen H, Aggernaes B, Langkilde AR, Paulson OB, Lublin H, Skimminge A, Baaré W. Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia. J Psychiatry Neurosci 2010;35(2):95-104
• Erritzøe D, Frøkjær VG, Haahr MT, Kalbitzer J, Svarer C, Holst KK, Hansen DL, Jernigan TL, Lehel S, Knudsen GM. Cerebral serotonin transporter binding is inversely related to body mass index. Neuroimage 2010;52(1):284-9
• Erritzøe D, Holst K, Frøkjær VG, Licht CL, Kalbitzer J, Nielsen FA, Svarer C, Madsen J, Knudsen G. A Nonlinear Relationship between Cerebral Serotonin Transporter and 5-HT2A Receptor Binding: An In Vivo Molecular Imaging Study in Humans. J Neurosci 2010;30(9):3391-7
• Ettrup A, Palner M, Gillings N, Santini MA, Hansen M, Kornum BR, Rasmussen LK, Någren K, Madsen J, Begtrup M, Knudsen GM. Radiosynthesis and evaluation of [11C]Cimbi-5 as a 5-HT2A receptor agonist radioligand for PET. J Nucl Med 2010;51(11):1763-70
• Frøkjær VG, Erritzøe D, Juul A, Nielsen FA, Holst K, Svarer C, Madsen J, Paulson OB, Knudsen GM. Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding. Psychoneuroendocrinology. 2010;35(9):1311-20
• Frøkjær VG, Vinberg M, Erritzøe D, Baaré W, Holst KK, Mortensen EL, Arfan H, Madsen J, Jernigan TL, Kessing LV, Knudsen GM. Familial risk for mood disorder and the personality risk factor, neuroticism, interact in their association with frontolimbic serotonin 2A receptor binding. Neuropsychopharmacology 2010;35(5):1129-37
• Hansen HH, Hansen G, Tang-Christensen M, Larsen PJ, Axel AM, Raben A, Mikkelsen JD. The novel triple monoamine reuptake inhibitor tesofensine induces sustained weight loss and improves glycemic control in the diet-induced obese rat: Comparison to sibutramine and rimonabant. Eur J Pharmacol 2010;636(1-3):88-95
• Holm P, Ettrup A, Klein AB, Santini MA, El-Sayed M, Elvang AB, Stensbøl TB, Mikkelsen JD,  Knudsen GM, Aznar S. Plaque deposition dependent decrease in 5-HT_2A serotonin receptor in APP**swe/PS1dE9 amyloid overexpressing mice. J Alzheimers Dis 2010;1;20(4):1201-13
• Kalbitzer J, Erritzoe D, Holst KK, Nielsen FA, Marner L, Lehel S, Arentzen T, Jernigan TL, Knudsen GM. Seasonal changes in brain serotonin transporter binding in short serotonin transporter linked polymorphic region-allele carriers but not in long-allele homozygotes. Biol Psychiatry. 2010;67(11):1033-9
• Kelsen J, Larsen MH, Sørensen JC, Møller A, Frøkiær J, Nielsen S, Nyengaard JR, Mikkelsen JD, Rønn LC. Neuronal precursor cell proliferation in the hippocampus after transient cerebral ischemia: a comparative study of two rat strains using stereological tools. Exp Transl Stroke Med 2010;6;2:8
• Kiss A, Bundzikova J, Pirnik Z, Mikkelsen JD. Different antipsychotics elicit different effects on magnocellular oxytocinergic and vasopressinergic neurons as revealed by Fos immunohistochemistry. J Neurosci Res 2010;88(3):677-85
• Klein AB, Santini MA, Aznar S, Knudsen GM, Rios M. Changes in 5-HT(2A)-mediated behavior and 5-HT(2A)- and 5-HT(1A) receptor binding and expression in conditional brain-derived neurotrophic factor knock-out mice. Neuroscience 2010;169(3):1007-16
• Klein AB, Trajkovska V, Erritzøe D, Haugbøl S, Madsen J, Baaré W, Aznar S, Knudsen GM. Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels. J Cereb Blood Flow Metab 2010;30(11):e1-7
• Knudsen S, Mikkelsen JD, Bang B, Gammeltoft S. og Jennum PJ: Intravenous immunoglobulin treatment and screening for hypocretin neuron-specific autoantibodies in recent onset childhood narcolepsy with cataplexy: Neuropediatrics. 2010;41(5), 217-22
• Koefoed P, Woldby DPD, Hansen TO, Hansen ES, Knudsen GM, Bolwig TG, Rehfeld JF. Gene variations in the cholecystokinin system in patients with panic disorder. Psychiatr Genet 2010;20(2):59-64
• Kornum BR, Stott SR, Mattsson B, Wismann L, Ettrup A, Hermening S, Knudsen GM, Kirik D. Adeno-associated viral vector serotypes 1 and 5 targeted to the neonatal rat and pig striatum induce widespread transgene expression in the forebrain. Exp Neurol 2010;222:70-85
• Kramer V, Herth MM, Santini MA, Palner M, Knudsen GM, Rösch F. Structural combination of established 5-HT2A receptor ligands: New aspects of binding mode. Chem Biol Drug Des. 2010;76(4):361-6
• Kupers R, Chebat DR, Madsen KH, Paulson OB, Ptito M. Neural correlates of virtual route recognition in congenital blindness. Proc Natl Acad Sci U S A 2010;107(28):12716-21
• Licht CL, Kirkegaard L, Zueger M, Chourbaji S, Gass P, Aznar S, Knudsen GM. Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice. Neurochem Int 2010;56(4):603-10
• Licht CL, Knudsen GM, Sharp T. Effects of the 5-HT4 receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neurosci Lett. 2010;476(2):58-61
• Madsen KS, Baaré WF, Vestergaard M, Skimminge A, Ejersbo LR, Ramsøy TZ, Gerlach C, Akeson P, Paulson OB, Jernigan TL. Response inhibition is associated with white matter microstructure in children. Neuropsychologia 2010;48(4):854-62
• Marner L, Gillings N, Madsen K, Erritzøe D, Baaré WF, Svarer C, Hasselbalch SG, Knudsen GM. Brain Imaging of Serotonin 4 Receptors in Humans with [11C]SB207145-PET. NeuroImage 2010;50(3):855-61
• Mikkelsen JD, Thomsen MS, Hansen HH, Lichota J. Use of biomarkers in the discovery of novel anti-schizophrenia drugs. Drug Discov Today 2010;15(3-4):137-141
• Miskowiak KW, Vinberg M, Harmer CJ, Ehrenreich H, Knudsen GM, Macoveanu J, Hansen AR, Paulson OB, Siebner HR, Kessing LV. Effects of erythropoietin on depressive symptoms and neurocognitive deficits in depression and bipolar disorder. Trials. 2010;13;11:97
• Nielsen SB, Franzmann M, Basaiawmoit RV, Wimmer R, Mikkelsen JD, Otzen DE. beta-sheet aggregation of kisspeptin-10 is stimulated by heparin but inhibited by amphiphiles. Biopolymers. 2010;93(8):678-89
• Palner M, McCormick P, Gillings N, Begtrup M, Wilson AA, Knudsen GM. Radiosynthesis and ex vivo evaluation of (R)-(-)-2-chloro-N-[1-11C-propyl]n-propylnorapomorphine. Nucl Med Biol 2010;37(1):35-40
• Palner M, McCormick P, Parkes J, Knudsen GM, Wilson AA. Systemic catechol-O-methyl transferase inhibition enables the D1 agonist radiotracer R-[11C]SKF 82957. Nucl Med Biol 2010;37(7):837-43
• Paterson LM, Tyacke RJ, Nutt DJ, Knudsen GM. Measuring endogenous 5-HT release by emission tomography: promises and pitfalls. J Cereb Blood Flow Metab. 2010;30(10):1682-706
• Paulson OB, Hasselbalch SG, Rostrup E, Knudsen GM, Pelligrino D. Cerebral blood flow response to functional activation. J Cerebral Blood Flow Metab 2010;30(1):2-14
• Paulson OB, Højgaard, L. Kortlægning af hjernens fysiologi og funktioner – de danske bidrag og den danske udvikling. Medicinsk Teknologi og Informatik 2010;7(4):30-32
• Prabhakaran J, Majo JM, Milak MS, Kassir SA, Palner M, Savenkova L, Mali P, Arango V, Mann JJ, Parsey RV. Synthesis, in vitro and in vivo evaluation of [11C]MMTP: A potential PET ligand for mGluR1 receptors. Bioorg Med Chem Lett 2010;20(12):3499-501
• Rasmussen H, Erritzøe D, Andersen R, Ebdrup BH, Aggernaes B, Oranje B, Kalbitzer J, Madsen J, Pinborg LH, Baaré W, Svarer C, Lublin H, Knudsen G, Glenthoj B. Decreased frontal serotonin2A receptor binding in antipsychotic-naïve patients with first-episode schizophrenia. Arch Gen Psychiatry 2010;67(1):9-16
• Thomsen G, Knudsen GM. Procedure Guideline for Brain Perfusion SPECT Using 99mTc Radiopharmaceuticals 3.0. J Nucl Med Technol 2010;38(4):209
• Thomsen MS, Hansen HH, Mikkelsen JD. Opposite effect of phenycyclidine on activity-regulated cytoskeleton-associated protein (arc) in juvenile and adult limbic rat brain regions. Neurochem Int 2010;56(2):270-5
• Thomsen MS, Hansen HH, Timmerman DB, Mikkelsen JD. Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: from animal models to human pathophysiology. Curr Pharm Des 2010;16(3):323-43
• Thomsen MS, Hay-Schymidt A, Hansen HH, Mikkelsen JD. Distinct neural pathways mediate alpha7 nicotinic acetylcholine receptor-dependent activation of the forebrain. Cereb Cortex 2010;20(9):2092-102
• Thomsen MS, Hansen HH, Mikkelsen JD. Alpha 7 nicotinic receptor agonism mitigates phencyclidine-induced changes in synaptophysin and Arc gene expression in the mouse prefrontal cortex. Neurochem Int. 2010;57(7):756-61.
• Vinberg M, Frøkjær VG, Kessing LV. Coping styles in healthy individuals at risk of affective disorder. J Nerv Ment Dis 2010;198(1):39-44
• Vrang N, Meyre D, Froguel P, Jelsing J, Tang-Christensen M, Vatin V, Mikkelsen JD, Thirstrup K, Larsen LK, Cullberg KB, Fahrenkrug J, Jacobson P, Sjöström L, Carlsson LM, Liu Y, Liu X, Deng HW, Larsen PJ. The imprinted gene neuronatin is regulated by metabolic status and associated with obesity. Obesity (Silver Spring) 2010;18(7):1289-96
• Wellendorph P, Høg S, Sabbatini P, Pedersen MH, Martiny L, Knudsen GM, Frølund B, Clausen RP, Bräuner-Osborne H. N Novel radioiodinated GHB analogues for radiolabeling and photolinking of high-affinity GHB binding sites. J Pharmacol Exp Ther. 2010;335(2):458-64
• Ziebell M, Korbo L, Hasselbalch SG. [Lewy body dementia]. Ugeskr Laeger. 2010;31;172(22):1675-8
• Ziebell M, Pinborg LH, Thomsen G, de Nijs R, Svarer C, Wagner A, Knudsen GM. MRI-guided region-of-interest delineation is comparable to manual delineation in dopamine transporter SPECT quantification in patients: a reproducibility study. J Nucl Med Technol 2010;38(2):61-8
• Ziebell M, Holm-Hansen S, Thomsen G, Wagner A, Jensen P, Pinborg LH, Knudsen GM. Serotonin transporters in dopamine transporter imaging: A head-to-head comparison of dopamine transporter SPECT radioligands [123I]FP-CIT and [123I]PE2I. J Nucl Med 2010;51(12):1885-91