NRU annual report 2018

The 2018 NRU annual report has been published and is available for download here.

Patrick Fisher receives funding from Augustinusfonden

Congratulations to Patrick Fisher for receiving 100,000 DKK from Augustinus Fonden for the project "Determining serotonergic genetic variant effects on in-vivo human brain serotonin markers".
The project involves visiting post-doc Marie Spies (Austria) and deals with determining genetic effects on 5HT2A and 5HTT binding in healthy control.

Claus Svarer - 25 years work anniversary

It is a great pleasure to invite you all to come and celebrate Claus Svarer's 25 years work anniversary on -

Thursday, May 16 at 14:00
NRU, Rigshospitalet, entrance 69, 3rd floor
Juliane Maries Vej 28, 2100 København Ø

Please see the invitation here.

The reception is kindly sponsored by the Neuroscience Center.

Best regards,
Gitte Moos Knudsen
Professor, Head of NRU

Grant from Augustinus Fonden to Mikael Palner

Congratulations to Junior Group Leader Mikael Palner for receiving 100,000 DKK from Augustinus Fonden for the project "Neuronal circuits that leads to increase glutamatergic activity in the prefrontal cortex". 

New funding from Elsassfonden

Congratulations to NRU senior researcher Jens D. Mikkelsen for receiving a new research grant from Elsassfonden. The grant is worth 1 million DKK and is for the project entitled 'Synaptic vesicle glycoprotein 2A (SV2A) used as a novel biomarker of synaptogenesis in models of cerebral palsy (CP)'.

Project abstract: When the brain changes in response to stimuli it is referred as brain plasticity. When plasticity occurs, the individual nerve cells change their inner machinery, establish novel contacts (called synapses) to other nerve cells, and break others. However, all this occurs at the cellular level and we can only detect brain plasticity today if we remove the brain and study the synapses biochemically or in the microscope. This strongly limits our ability to determine if treatments are printed in the brain in real time. Most importantly, it also prevents our ability to observe changes in the brain of patients with neurological including cerebral palsy. This is very important, because such changes occur early in the disease processes. Very recent discovery of radiotracers that bind to the synaptic vesicle protein, synaptic vesicle glycoprotein 2A (SV2A) and imaging may revolutionize our ability to measure synaptic density in the living brain as an indicator of brain plasticity. We have already made significant progress in the validation of these radiotracers. In this project, using own synthesized radiotracers and validated methods, we will define the changes in binding and measure and correlate binding of these tracers in animal models of cerebral palsy as well as in fresh tissue from patients that underwent neurosurgical operation for epilepsy as an important contribution for novel diagnostics in psychiatry and neurology.

Fondsbørsvekselerer Henry Hansen og Hustru Karla Hansens Legat

Congratulations to NRU senior researcher Lars H. Pinborg, who has received the 'Fondsbørsvekselerer Henry Hansen og Hustru Karla Hansens Legat' worth 350.000 DKK for his research in preoperative diagnosis of patients examined for epilepsy surgery. The award has been given based on a recommendation from an advisory committee at the University of Copenhagen.

New FSS grants to NRU researchers

Congratulations to Louise Møller Jørgensen for receiving from the Independent Research Fund Denmark (FSS) a Clinician Scientist Position grant worth 1.039.248 DKK for her part-time research project "Deep Brain Stimulation: Effects on cerebral blood flow, brain circuits and neurotransmission". Also, congratulations to Gitte Moos Knudsen for receiving a scholar stipend grant worth 103.100 DKK for the project "Neural correlates of the personality dimension openness to experience: a resting state fMRI study in healthy participants".

Major grant from the Lundbeck Foundation for 5-year thematic alliance within precision medicine in epilepsy and depression

Professor Gitte Moos Knudsen, head of NRU, has received a major grant worth 40 million Danish kroner from the Lundbeck Foundation for a highly ambitious thematic alliance called BrainDrugs. Perfectly aligned with the National Strategy for Personalized Medicine 2017-2020, the aim of the new thematic alliance is to establish which key features predict drug response in patients with epilepsy or depression. The BrainDrugs consortium is composed of a multidisciplinary team of experienced investigators from The Capital Region, Aarhus and the specialized epilepsy hospital Filadelfia, assisted by two international experts within the field. The project will start July 1st, 2019 and run for five years.

Read more ...

PhD defence: Marie Deen

On Friday, January 4, at 2 PM, Marie Deen, MD, will defend her PhD dissertation entitled "PET investigations of brain serotonin receptor binding in  migraine patients".

The defence will take place in Auditorium C, Rigshospitalet Glostrup, Valdemar Hansens Vej 5, 2600 Glostrup.

Read more ...

Travel stipend for Giske Opheim

Congratulations to Giske Opheim for receiving DKK 19,253 from Lennart Grams Mindefond for her participation at the 72nd Annual Meeting of the American Epilepsy Society in New Orleans (Nov 30-Dec 4, 2018).